Circulatory

• Mild decrease in blood pressure during use.
• Mild decrease in overall blood pressure with long term use.

Adverse Side Effects (THC only) can include a temporary increase in heart rate.

Optical

• Lowers pressure in eyes (effective for glaucoma)

Adverse Side Effects (THC only) can include dry eyes and reddening of whites of eyes.

Muscular-skeletal

• Reduces muscle spasms, spasticity, tics and tremors.
• Reduces ataxia.
• Decreases inflammation in joints (effective for arthritis).

Adverse Side Effects (THC only) can include decreased coordination.

Digestive (Stomach, Small and Large Intestines)

• Reduces intestinal muscle spasms (effective for colitis and IBS).
• Stimulates appetite.
• Decreases nausea and vomiting (effective for chemotherapy and other conditions).
• Decreases intestinal inflammation (effective for colitis).

Immune System

• Suppresses inflammation (effective for arthritis, immune-mediated illnesses).

Possible Side-Effects of Long-Term Heavy THC Use

• Mood disturbance with chronic heavy use of THC (depression, apathy, social isolation).
• Withdrawal symptoms including irritability, insomnia, anxiety and depression. Avoid these long term side-effects by abstaining from cannabis use for 1-2 weeks every 3 months if daily user, or for those who cannot take time off due to severe medical conditions, changing chemovars, CBD:THC ratios or methods of use can help minimize or prevent withdrawal.