Index

Adjuvant! Genomic 59

Adjuvant! Online 34, 57

adjuvant therapy 14, 51–61

ado-trastuzumab emtansine 56

adverse effects see side effects

age 9, 13, 55

alcohol consumption 12

anastrozole 52

anatomy 7–8

anthracyclines 54, 59

antiplatelet agents 41

anxiety 67

aromatase inhibitors 52, 53

axillary lymph nodes 19, 24, 30–2, 43–4

benign disease 26, 28

biological therapy 37, 54–6

biopsy 20, 25, 26–7

sentinel node 40, 44

bisphosphonates 57

BRCA1/BRCA2 13, 56

breast-conserving surgery 39, 40, 41–3, 67

carboplatin 55

cardiac toxicity 47, 55, 59

chemotherapy

adjuvant 14, 53–5, 57

neoadjuvant 36–8, 44

side effects 54, 59, 61

clinical examination 20, 23–4

cognitive impairment 59

Cooper’s ligaments 8, 24

cysts 26

cytochrome P450 51, 52

cytology 20, 25, 26

definitions 7

depression 67

diagnosis 17–28

DIEP flap reconstruction 45

diet 12

dimpling of the skin 8, 18, 24

docetaxel 54, 55

ductal carcinoma 8

ductal carcinoma in situ (DCIS) 7

ELIOT therapy 48

endocrine therapy 36, 51–3, 57

endometrial cancer 52

environmental risk factors 11–12

epidemiology 7, 9–13

ER (estrogen receptor)-positive cancer 9, 33, 51–3, 57

everolimus 56

exemestane 52, 53

exercise 12

family history 11

fertility 61

fine needle aspiration cytology (FNAC) 20, 25, 26

follow-up 65–6

gene expression profiles 33, 59–60

genetic risk 11, 13

geographic risk 11

GnRH analogs 53, 61

goserelin 53, 61

grade of tumor 32

HER2-positive cancer 9, 33, 37, 54–5, 55–6, 57

history 11, 21–2

hormonal therapy 36, 51–3, 57

hormone replacement therapy 12

imaging 8, 20, 24–6, 66

implants 42

incidence 7

lapatinib 56

letrozole 52

leukopenia 59

lipofilling 45

lobular carcinoma 8

lumpectomy 39, 40, 41–3, 67

lymph nodes 19, 24, 30–2, 43–4

lymphedema, arm 41, 66

mammography 13, 17–18, 24–5, 65–6

mammoplasty 42

MammoSite technique 48

mastalgia 18

mastectomy 39–41, 44–5

prophylactic 26, 66

rehabilitation 66–7

mastopexy 42

menstrual history 11

metastatic risk 12, 51

Mobitron system 48

mortality rates 7

MRI (magnetic resonance imaging) 19, 25–6, 66

mTOR inhibitors 56

multiple tumors 41

nab-paclitaxel 37–8

neoadjuvant therapy 36–8, 44, 48

night work 12

nipple bleeding/discharge 19, 24

nipple conservation 39–40

nipple inversion 24

Nottingham Prognostic Index (NPI) 33

nurse counselors 67

nutrition 12

obesity 12

oral contraceptives 11

osteoporosis 52

ovarian suppression 53

overdiagnosis 18, 25

paclitaxel 37–8, 54, 55, 59

pain, breast 18

pathology 8–9, 26–7

pertuzumab 37

phyllodes tumors 8

physical activity 12

physical examination 20, 23–4

physiotherapy 66

poly ADP-ribose polymerase inhibitors 56

pregnancy 11, 61

premenopausal women 14, 53, 61

progesterone receptors 9, 33

prognosis 32, 33–4, 57–9, 60

prophylactic mastectomy 26, 66

prostheses 66

psychological rehabilitation 67

radiotherapy 36, 43–4, 46–7, 48

intraoperative 18, 41–2, 47–8

reconstructive surgery 40, 44–5

recurrence risk 12, 14, 32, 37, 47, 57

rehabilitation 66–7

reproductive history 11

risk:benefit analysis 14, 37

risk factors 9–15, 22

Scarf–Bloom–Richardson scale 32

screening 17–18

self-examination 18

sentinel lymph nodes 40, 43, 44

side effects

of adjuvant therapies 52, 54, 59, 61

of radiotherapy 46–7

of surgery 40–1, 45

signs and symptoms 8, 18–19

size/shape of the breast 19, 42

skin-sparing mastectomy 39–40

smoking 12

staging 7, 30–2, 34

subtypes 33

surgery 36, 39–44, 48

after an MRI 25–6

reconstruction 40, 44–5

rehabilitation 66–7

risks of delay 37

surveillance 65–6

survivorship 65–8

symptoms 8, 18–19

tamoxifen 51–2

targeted therapy 37, 55–6

TARGIT (intraoperative radiotherapy) 18, 41–2, 47–8

taxanes 37–8, 54, 55, 59

thromboembolism 52

TNM staging 30–2

tomosynthesis 24–5

trastuzumab (Herceptin) 37, 55–6, 57

treatment see chemotherapy; radiotherapy; surgery

triple assessment 19–27

triple-negative cancer 33, 38, 55

ultrasonography 20, 25

vacuum-assisted biopsy 26–7

volunteer groups 67

wide local excision 39, 40, 41–3, 67

Xoft technique 48

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