Photograph 51 by Anna Ziegler received its UK Premiere in London on 5th September 2015 at the Noël Coward Theatre, produced by the Michael Grandage Company.
| Cast (in order of speaking) | |
| ROSALIND FRANKLIN | Nicole Kidman |
| MAURICE WILKINS | Stephen Campbell Moore |
| JAMES WATSON | Will Attenborough |
| FRANCIS CRICK | Edward Bennett |
| DON CASPAR | Patrick Kennedy |
| RAY GOSLING | Joshua Silver |
Understudies |
|
| ROSALIND FRANKLIN | Lorna Stuart |
| MAURICE WILKINS/ | William Troughton |
| FRANCIS CRICK/ | |
| DON CASPAR/ | |
| JAMES WATSON/ | Patrick Walshe McBride |
| RAY GOSLING | |
Creative team |
|
| Director | Michael Grandage |
| Set and Costume Designer | Christopher Oram |
| Lighting Designer | Neil Austin |
| Composer and Sound Designer | Adam Cork |