From aspirin and bananas to Marmite and water, you may hear endless remedies to prevent or treat hangovers from your friends, family members and the Internet. Unfortunately, no scientific evidence supports any cure or effective prevention for alcohol hangovers. In a systematic review of randomized trials asking if anything worked to prevent or treat hangovers, no effective interventions were found in either the traditional or complementary medical literature. While a few very small studies showed minor improvements, these studies did not use a standardized system to measure how people felt. The conclusion of the exhaustive review of all the studies was that nothing that had been studied worked: not propranolol, tropisetron, tolfenamic acid, fructose, glucose, nor dietary supplements including borage, artichoke, prickly pear or a yeast-based product. The effective hangover cure is, unfortunately, a myth. While more recent studies in rats show some potential for new products to alter the mechanisms in your body that might cause hangover symptoms, humans also can get ill from some kinds of ‘hangover cures’. A hangover is caused when you drink too much alcohol. Thus the most effective way to avoid a hangover is to drink alcohol only in moderation or not at all.