Praise for

The Breakthrough

“Fascinating… An untold story… that Siddhartha Mukherjee’s 2001 Emperor of All Maladies… barely even acknowledged.”

New York Times Book Review (An Editor’s Choice Book)

“A great book, a must-read.”

—Dr. James L. Gulley, M.D. Ph.D., Chief of Oncology, National Cancer Institute (NCI)

“Fascinating. Artful. If you or a loved one… has cancer… this book and the advances it describes offer far more than the usual glimmer of hope.”

New York Times

“If you or a loved one has cancer, this is a book you’ll want to pick up.”

—Dana Perino, FOX Nation

“Gripping. Riveting. A terrific book.”

—Sharon Begley, Washington Post

“This is your new survival manual.”

—William Ferrall

“Captivating… the subject of Mr. Graeber’s engaging chronicle is the science of helping our bodies fight back.”

—David A. Shaywitz, Wall Street Journal

“A top medical book of the year.”

—British Medical Association, 2019 Book Award shortlist

“Gift this to partners, children, parents, and friends.”

—Carolyn Wong Simpkins, Science Magazine

“Brilliant. Reads like a crime thriller because that’s what it is. ”

Financial Review

“Extraordinary.”

Sydney Morning Herald

“Rare and thrilling… a hopeful, even inspiring, book about cancer.”

—Chris Hewitt, Minneapolis Star Tribune

“Fantastic.”

Wired “Top Science Books”

“Brilliantly rendered… terrific, compelling… pulls you into the narrative right off the top and never lets go.”

—Douglas J. Johnston, Winnipeg Free Press

“Fascinating.”

National Book Review “Five Hot Books”

“Crisp and suspenseful… the perfect backstory for this year’s Nobel Prize in Medicine.”

—Jane Ciabattari, BBC “Ten Books to Read This Month”

“Lucid and informed.”

Publishers Weekly

“Exciting reading.”

Booklist

“Fascinating, well-researched, and accessible. A great read. Read it.”

—Lisa H. Butterfield, Ph.D., President, SITC (Society for Immunotherapy of Cancer, 2016–2018), and Vice President, Parker Institute for Cancer Immunotherapy

“Offers something rare: realistic hope.”

Washington Post

“A wonderful book and a wonderful resource, for scientists and non-scientists alike.”

—Dr. Robert Schrieber, celebrated immunologist and co-recipient of the 2017 Balzan Prize (together with Nobel winner Dr. James P. Allison)

“Expertly crafted and exhilarating. You will never encounter another book so incisive about the art of medical sleuthing, or so poetic about our innate drive to hold on to all that’s beautiful in this world for as long as we can.”

—Brendan I. Koerner, Wired contributing editor and author of The Skies Belong to Us

“Gripping for myself and millions of other cancer survivors, THE BREAKTHROUGH is a book of immense and essential hope.”

—Michael Fitzgerald, co-founder and CEO of Submittable and author of Radiant Days

“Only Graeber, one of America’s greatest nonfiction writers, could take a subject so complex, dense, and sprawling and turn it into a rollicking high-tension medical thriller. Masterful.”

—Douglas Rogers, award-winning journalist and author of The Last Resort and Two Weeks in November

“Graeber does it again. He takes a complex topic—this time advances in cancer treatment—and weaves a narrative that engages you to the end. With cancer as a leading cause of illness and death, this book is a timely and important account of the challenges and possibilities for new horizons in cancer treatment.”

—Diana J. Mason, Ph.D., Senior Policy Service Professor (George Washington University School of Nursing), Professor Emerita (Hunter College, CUNY)

“We can’t fail to see ourselves, our friends, and our families in these stories.”

—David A. Shaywitz, Wall Street Journal