This list includes all the published case studies discussed in each chapter, in addition to a mix of relevant published scientific research studies, online science and newspaper articles, books, and other relevant guidelines and websites. It is not exhaustive, but is intended to provide the interested reader with further material relevant to each chapter.
1 YOUR SEXIEST BRAIN BITS
Baird, A.D., Wilson, S.J., Bladin, P.B., Saling, M.M., & Reutens, D.C. (2004). The amygdala and sexual drive: Insights from temporal lobe epilepsy surgery. Annals of Neurology, 55(1), 87–96.
—— (2007). Neurological control of human sexual behaviour: Insights from lesion studies. Journal of Neurology, Neurosurgery, and Psychiatry, 78(10), 1042–1049.
Brown, S., & Schäfer, E.A. (1888). An investigation into the functions of the occipital and temporal lobes of the monkey’s brain. Philosophical Transactions of the Royal Society of London. B, 179, 303–327.
Diamond, J. (1997/2015). Why is Sex Fun? The evolution of human sexuality. London: Weidenfeld & Nicolson.
Klüver, H., & Bucy, P.C. (1939). Preliminary analysis of functions of the temporal lobes in monkeys. Archives of Neurology & Psychiatry, 42, 979–1000.
Lilly, R., Cummings, J.L., Benson, F., & Frankel, M. (1983). The human Klüver-Bucy syndrome. Neurology, 33(9), 1141–1145.
Marlowe, W.B., Mancall, E.L., & Thomas, J.J. (1975). Complete Klüver-Bucy syndrome in man. Cortex, 11(1), 53–59.
Terzian, H., & Dalle Ore, G. (1955). Syndrome of Klüver and Bucy, reproduced in man by bilateral removal of the temporal lobes. Neurology, 5(6), 374–380.
2 ‘GIVE IT TO ME BABY’ OR ‘NOT TONIGHT, DARLING’
Ahmed, R., Kaizik, C., Irish, M., Mioshi, E., Dermody, N., Kiernan, M.C.,…Hodges, J.R. (2015). Characterizing sexual behavior in frontotemporal dementia. Journal of Alzheimer’s Disease, 46(3), 677–686.
Aull-Watschinger, S., Pataraia, E., & Baumgartner, C. (2008). Sexual auras: Predominance of epileptic activity within the mesial temporal lobe. Epilepsy & Behavior, 12(1), 124–127.
Blumer, D. (1970). Changes of sexual behavior related to temporal lobe disorders in man. Journal of Sex Research, 6(3), 173–180.
Janszky, J., Ebner, A., Szupera, Z., Schulz, R., Hollo, A., Szücs, A., & Clemens, B. (2004). Orgasmic aura – a report of seven cases. Seizure, 13(6), 441–444.
Ozkara, C., Ozdemir, S., Yilmaz, A., Uzan, M., Yeni, N., & Ozmen, M. (2006). Orgasm-induced seizures: A study of six patients. Epilepsia, 47(12), 2193–2197.
Rémillard, G.M., Andermann, F., Testa, G.F., Gloor, P., Aube, M., Martin, J.B.,…Simpson, C. (1983). Sexual ictal manifestations predominate in women with temporal lobe epilepsy: A finding suggesting sexual dimorphism in the human brain. Neurology, 33(3), 323–330.
Spencer, S.S., Spencer, D.D., Williamson, P.D., & Mattson, R.H. (1983). Sexual automatisms in complex partial seizures. Neurology, 33(5), 527–533.
Stoléru, S., Fonteille, V., Cornélis, C., Joyal, C., & Moulier, V. (2012). Functional neuroimaging studies of sexual arousal and orgasm in healthy men and women: A review and meta-analysis. Neuroscience & Biobehavioral Reviews, 36(6), 1481–1509.
Wise, N., Frangos, E., & Komisaruk, B.R. (2016). Activation of sensory cortex by imagined genital stimulation: An fMRI analysis. Socioaffective Neuroscience & Psychology, 6, 31481.
—— (2017). Brain activity unique to orgasm in women: An fMRI analysis. Journal of Sexual Medicine, 14(11), 1380–1391.
Zhang, S., Dissanayaka, N., Dawson, A., O’Sullivan, J.D., Mosley, P., Hall, W., & Carter, A. (2016). Management of impulse control disorders in Parkinson’s disease. International Psychogeriatrics, 28(10), 1597–1614.
3 SEXUAL SIDE EFFECTS OF SEIZURE SURGERY
Asadi-Pooya, A.A, & Rostami, C. (2017). History of surgery for temporal lobe epilepsy. Epilepsy & Behavior, 70(A), 57–60.
Baird, A.D., Wilson, S.J., Bladin, P.B., Saling, M.M., & Reutens, D.C. (2002). Hypersexuality after temporal lobe resection. Epilepsy & Behavior, 3(2), 173–181.
—— (2003). Sexual outcome after epilepsy surgery. Epilepsy & Behavior, 4(3), 268–278.
Bladin, P.F., Wilson, S.J., Saling, M.M., Kincade, P., McIntosh, A., & O’Shea, M.F. (1999). Outcome assessment in seizure surgery: The role of postoperative adjustment. Journal of Clinical Neuroscience, 6(4), 313–318.
Rippon, G. (2019). The Gendered Brain: The new neuroscience that shatters the myth of the female brain. London: Bodley Head.
Ritchie, S.J., Cox, S.R., Shen, X., Lombardo, M.V., Reus, L.M., Alloza, C.,…Deary, I.J. (2018). Sex differences in the adult human brain: Evidence from 5216 UK Biobank participants. Cerebral Cortex, 28(8), 2959–2975.
Wilson, S.J., Bladin, P.F., & Saling, M.M. (2001). The ‘burden of normality’: Concepts of adjustment after surgery for seizures. Journal of Neurology, Neurosurgery, and Psychiatry, 70, 649–656.
4 STIMULATION, SHUNTS AND PSYCHOSURGERY
Conley, G. (2016). Boy Erased: A memoir. New York: Riverhead Books.
de Boisanger, L., & Kaliaperumal, C. (2018). Letter: Sex after neurosurgery – is it safe? Neurosurgery, 82(2), E67–E68.
Demetriades, P., Rickards, H., & Cavanna, A.E. (2011). Impulse control disorders following deep brain stimulation of the subthalamic nucleus in Parkinson’s disease: Clinical aspects. Parkinson’s Disease, 2011, 1–9.
Gorman, D.G., & Cummings, J.L. (1992). Hypersexuality following septal injury. Archives of Neurology, 49(3), 308–310.
Heath, R.G. (1964). Pleasure response of human subjects to direct stimulation of the brain: Physiologic and psychodynamic considerations. In R.G. Heath (ed.), The role of pleasure in behavior (pp. 219–243). New York: Harper & Row.
—— (1972). Pleasure and brain activity in man: Deep and surface electroencephalograms during orgasm. Journal of Nervous and Mental Disease, 154(1), 3–18.
Kesey, K. (1962). One Flew Over the Cuckoo’s Nest. New York: Viking.
Moan, C.E., & Heath, R.G. (1972). Septal stimulation for the initiation of heterosexual behavior in a homosexual male. Journal of Behavior Therapy and Experimental Psychiatry, 3(1), 23–26.
Rieber, I., & Sigusch, V. (1979). Psychosurgery on sex offenders and sexual ‘deviants’ in West Germany. Archives of Sexual Behavior, 8(6), 523–527.
Schmidt, G., & Schorsch, E. (1981). Psychosurgery of sexually deviant patients: Review and analysis of new empirical findings. Archives of Sexual Behavior, 10(3), 301–323.
5 CAN SEX CHANGE YOUR BRAIN?
Blaxendale, S. (2004). Memories aren’t made of this: Amnesia at the movies. British Medical Journal, 329, 1480–1482.
el Gaddal, Y.Y. (1989). De Clérambault’s syndrome (erotomania) in organic delusional syndrome. British Journal of Psychiatry, 154(5), 714–716.
Foreman, P.M., Griessenauer, C.J., Selim, M.H., Searls, D E.C., Safdar, A., Kasper, E.M.,…Thomas, A.J. (2016). Sexual activity as a trigger for intracranial hemorrhage. Acta Neurochirurgica, 158(1), 189–195.
Inzitari, D., Pantoni, L., Lamassa, M., Pallanti, S., Pracucci, G., & Marini, P. (1997). Emotional arousal and phobia in transient global amnesia. Archives of Neurology, 54(7), 866–873.
Kaplan, H.S. (1979). Disorders of sexual desire and other new concepts and techniques in sex therapy. New York: Brunner/Mazel.
Maloy, K., & Davis, J.E. (2011). ‘Forgettable’ sex: A case of transient global amnesia presenting to the emergency department. Journal of Emergency Medicine, 41(3), 257–260.
Masters, W.H., & Johnson, V.E. (1966). Human Sexual Response. Boston: Little, Brown.
Reynolds, M.R., Willie, J.T., Zipfel, G.J., & Dacey Jr., R.G. (2011). Sexual intercourse and cerebral aneurysmal rupture: Potential mechanisms and precipitants: A review. Journal of Neurosurgery, 114(4), 969–977.
Shorvon, S.D. (2011). The causes of epilepsy: Changing concepts of etiology of epilepsy over the past 150 years. Epilepsia, 52(6), 1033–1044.
Sieveking, E. (1858). On epilepsy and epileptiform seizures: Their causes, pathology and treatment. London: John Churchill.
Simons, J.S., & Hodges, J.R. (2000). Transient global amnesia. Neurocase, 6(3), 211–230.
Stoléru, S., Fonteille, V., Cornélis, C., Joyal, C., & Moulier, V. (2012). Functional neuroimaging studies of sexual arousal and orgasm in healthy men and women: A review and meta-analysis. Neuroscience & Biobehavioral Reviews, 36(6), 1481–1509.
Tissot, S.A.D. (1767). Onanism: Or, a treatise upon the disorders produced by masturbation (A. Hume, Transl.). London: A. Hume.
6 WHAT’S LOVE GOT TO DO WITH IT?
Baird, A., & Thompson, W.F. (2018). When music compensates language: A case study of severe aphasia in dementia and the use of music by a spousal caregiver. Aphasiology, 33(4), 449–465.
Eisenberger, N.I. (2012). The neural bases of social pain: Evidence for shared representations with physical pain. Psychosomatic Medicine, 74(2), 126–135.
el Gaddal, Y.Y. (1989). De Clérambault’s syndrome (erotomania) in organic delusional syndrome. British Journal of Psychiatry, 154(5), 714–716.
Fisher, H.E., Brown, L.L., Aron, A., Strong, G., & Mashek, D. (2010). Reward, addiction, and emotion regulation systems associated with rejection in love. Journal of Neurophysiology, 104(1), 51–60.
Fisher, H.E., Xu, X., Aron, A., & Brown, L.L. (2016). Intense, passionate, romantic love: A natural addiction? How the fields that investigate romance and substance abuse can inform each other. Frontiers in Psychology, 7, 687.
Fletcher, G.J., Simpson, J.A., Campbell, L., & Overall, N.C. (2015). Pair-bonding, romantic love, and evolution: The curious case of Homo sapiens. Perspectives on Psychological Science, 10(1), 20–36.
Jordan, H.W., & Howe, G. (1980). De Clerambault syndrome (erotomania): A review and case presentation. Journal of the National Medical Association, 72(10), 979–985.
Kawamichi, H., Sugawara, S.K., Hamano, Y.H., Makita, K., Matsunaga, M., Tanabe, H.C.,…Sadato, N. (2016). Being in a romantic relationship is associated with reduced gray matter density in striatum and increased subjective happiness. Frontiers in Psychology, 7, 1763.
Kross, E., Berman, M.G., Mischel, W., Smith, E.E., & Wager, T.D. (2011). Social rejection shares somatosensory representations with physical pain. Proceedings of the National Academy of Sciences, 108(15), 6270– 6275.
Olojugba, C., de Silva, R., Kartsounis, L.D., Royan, L., & Carter, J. (2007). De Clerambault’s syndrome (erotomania) as a presenting feature of fronto-temporal dementia and motor neurone disease (FTDMND). Behavioural Neurology, 18(3), 193–195.
Song, H., Zou, Z., Kou, J., Liu, Y., Yang, L., Zilverstand, A.,…Zhang, X. (2015). Love-related changes in the brain: A resting-state functional magnetic resonance imaging study. Frontiers in Human Neuroscience, 9, 71.
Sturm, V.E., Yokoyama, J.S., Eckart, J.A., Zakrzewski, J., Rosen, H.J., Miller, B.L.,…Levenson, R.W. (2015). Damage to left frontal regulatory circuits produces greater emotional reactivity in frontotemporal dementia. Cortex, 64, 55–67.
Xu, X., Brown, L., Aron, A., Cao, G., Feng, T., Acevedo, B., & Weng, X. (2012). Regional brain activity during early-stage intense romantic love predicted relationship outcomes after 40 months: An fMRI assessment. Neuroscience Letters, 526(1), 33–38.
7 FROM SAFETY PINS TO SLEEPING BEAUTIES
American Psychiatric Association. (2013). Diagnostic and Statistical Manual of Mental Disorders: DSM-5 (5th ed.). Washington, DC: American Psychiatric Association.
Ballard, J.G. (1973). Crash. London: Jonathan Cape.
Bianchi-Demicheli, F., Rollini, C., Lovblad, K., & Ortigue, S. (2010). ‘Sleeping Beauty paraphilia’: Deviant desire in the context of bodily self-image disturbance in a patient with a fronto-parietal traumatic brain injury. Medical Science Monitor, 16(2), C15–C17.
Burns, J.M., & Swerdlow, R.H. (2003). Right orbitofrontal tumor with pedophilia symptom and constructional apraxia sign. Archives of Neurology, 60(3), 437–440.
Devinsky, J., Sacks, O., & Devinsky, O. (2010). Klüver-Bucy syndrome, hypersexuality, and the law. Neurocase, 16(2), 140–145.
Fumagalli, M., Pravettoni, G., & Priori, A. (2015). Pedophilia 30 years after a traumatic brain injury. Neurological Sciences, 36(3), 481–482.
Mendez, M., & Shapira, J.S. (2011). Pedophilic behavior from brain disease. Journal of Sexual Medicine, 8(4), 1092–1100.
Mitchell, W., Falconer, M., & Hill, D. (1954). Epilepsy with fetishism relieved by temporal lobectomy. Lancet, 264(6839), 626–630.
Mohnke, S., Mueller, S., Amelung, T., Krüger, T.H., Ponseti, J., Schiffer, B.,…Walter, H. (2014). Brain alterations in paedophilia: A critical review. Progress in Neurobiology, 122, 1–23.
Ortego, N., Miller, B.M., Itabashi, H., & Cummings, J.L. (1993). Altered sexual behavior with multiple sclerosis: A case report. Neuropsychiatry, Neuropsychology, and Behavioral Neurology, 6(4), 260–264.
Sacks, O. (2019). Urge. In O. Sacks, Everything In Its Place: First loves and last tales (pp. 108–113). New York: Knopf.
Tenbergen, G., Wittfoth, M., Frieling, H., Ponseti, J., Walter, M., Walter, H.,…Kruger, T.H. (2015). The neurobiology and psychology of pedophilia: Recent advances and challenges. Frontiers in Human Neuroscience, 9, 344.
American Psychiatric Association. (2013). Diagnostic and Statistical Manual of Mental Disorders: DSM-5 (5th ed.). Washington, DC: American Psychiatric Association.
Baird, A. (2009). University challenge: A student with Asperger Syndrome shares his rage. Paper presented at the Asia Pacific Autism Conference, 20–22 August, Sydney.
Barahona-Corrêa, J.B., & Filipe, C.N. (2016). A concise history of Asperger Syndrome: The short reign of a troublesome diagnosis. Frontiers in Psychology, 6, 2024
Chandradasa, M., & Champika, L. (2017). Zoophilia in an adolescent with high-functioning autism from Sri Lanka. Australasian Psychiatry, 25(5), 486–488.
Ecker, C. (2017). The neuroanatomy of autism spectrum disorder: An overview of structural neuroimaging findings and their translatability to the clinical setting. Autism, 21(1), 18–28.
Fernandes, L.C., Gillberg, C.I., Cederlund, M., Hagberg, B., Gillberg, C., & Billstedt, E. (2016). Aspects of sexuality in adolescents and adults diagnosed with autism spectrum disorders in childhood. Journal of Autism and Developmental Disorders, 46(9), 3155–3165.
Schöttle, D., Briken, P., Tüscher, O., & Turner, D. (2017). Sexuality in autism: Hypersexual and paraphilic behavior in women and men with high-functioning autism spectrum disorder. Dialogues in Clinical Neuroscience, 19(4), 381–393.
Silberman, S. (2015). NeuroTribes: The legacy of autism and the future of neurodiversity. London: Penguin.
van Rooij, D., Anagnostou, E., Arango, C., Auzias, G., Behrmann, M., Busatto, G.F.,…Buitelaar, J.K. (2017). Cortical and subcortical brain morphometry differences between patients with autism spectrum disorder and healthy individuals across the lifespan: Results from the ENIGMA ASD working group. American Journal of Psychiatry, 175(4), 359–369.
9 PORN ON THE TRAIN (AND ON THE BRAIN)
American Psychiatric Association. (1987). Diagnostic and Statistical Manual of Mental Disorders: DSM-III-R (3rd rev. ed.). Washington, DC: American Psychiatric Association.
Kraus, S.W., Krueger, R.B., Briken, P., First, M.B., Stein, D.J., Kaplan, M.S.,…Reed, G.M. (2018). Compulsive sexual behaviour disorder in the ICD-11. World Psychiatry, 17(1), 109–110.
Kühn, S., & Gallinat, J. (2014). Brain structure and functional connectivity associated with pornography consumption: The brain on porn. JAMA Psychiatry, 71(7), 827–834.
—— (2016). Neurobiological basis of hypersexuality. International Review of Neurobiology, 129, 67–83.
Ley, D.J. (2012). The Myth of Sex Addiction. Lanham, MD: Rowman & Littlefield.
Meurk, C., Carter, A., Partridge, B., Lucke, J., & Hall, W. (2014). How is acceptance of the brain disease model of addiction related to Australians’ attitudes towards addicted individuals and treatments for addiction? BMC Psychiatry, 14, 373.
Prause, N. (2017). Evaluate models of high-frequency sexual behaviors already. Archives of Sexual Behavior, 46(8), 2269–2274.
Rush, B. (1812). Medical inquiries and observations upon the diseases of the mind. Philadelphia: Kimber & Richardson.
Satel, S., & Lilienfeld, S.O. (2013). Addiction and the brain-disease fallacy. In S. Satel & S.O. Lilienfeld (eds), Brainwashed: The seductive appeal of mindless neuroscience (pp. 49–72). New York: Basic Books.
Seok, J.-W., & Sohn, J.-H. (2015). Neural substrates of sexual desire in individuals with problematic hypersexual behavior. Frontiers in Behavioral Neuroscience, 9, 321.
—— (2018). Gray matter deficits and altered resting-state connectivity in the superior temporal gyrus among individuals with problematic hypersexual behavior. Brain Research, 1684, 30–39.
Sescousse, G., Caldú, X., Segura, B., & Dreher, J.C. (2013). Processing of primary and secondary rewards: A quantitative meta-analysis and review of human functional neuroimaging studies. Neuroscience & Biobehavioral Reviews, 37(4), 681–696.
10 BLAME IT ON MY BRAIN
Bartlett, F., Hall, W., & Carter, A. (2013). Case and comment. Tasmania v Martin (No 2): Voluntariness and causation for criminal offending associated with treatment of Parkinson’s disease. Criminal Law Journal, 37(5), 330–341.
Blair, R.J., & Cipolotti, L. (2000). Impaired social response reversal: A case of ‘acquired sociopathy’. Brain, 123(6), 122–141.
Burns, J.M., & Swerdlow, R.H. (2003). Right orbitofrontal tumor with pedophilia symptom and constructional apraxia sign. Archives of Neurology, 60(3), 437–440.
Carter, A., Ambermoon, P., & Hall, W.D. (2009). Drug-induced impulse control disorders: A prospectus for neuroethical analysis. Neuroethics, 4(2), 91–102.
Damasio H, Grabowski T, Frank R, Galaburda AM, Damasio AR. (1994). The Return of Phineas Gage: Clues about the brain from the skull of a famous patient. Science, 264(5162):1102–5.
Devinsky, J., Sacks, O., & Devinsky, O. (2010). Klüver-Bucy syndrome, hypersexuality, and the law. Neurocase, 16(2), 140–145.
Eslinger, P.J., & Damasio, A.R. (1985). Severe disturbance of higher cognition after bilateral frontal ablation: Patient EVR. Neurology, 35(12), 1731–1741.
Mobbs, D., Lau, H.C., Jones, O.D., & Frith, C.D. (2007). Law, responsibility, and the brain. PLoS Biology, 5(4), e103.
Munhoz, R.P., Fabiani, G., Becker, N., & Teive, H.A. (2009). Increased frequency and range of sexual behavior in a patient with Parkinson’s disease after use of pramipexole: A case report. Journal of Sexual Medicine, 6(4), 1177–1180.
Ortego, N., Miller, B.M., Itabashi, H., & Cummings, J.L. (1993). Altered sexual behavior with multiple sclerosis: A case report. Neuropsychiatry, Neuropsychology, and Behavioral Neurology, 6(4), 260–264.
Sacks, O. (2019). Urge. In O. Sacks, Everything In Its Place: First loves and last tales (pp. 108–113). New York: Knopf.