Identifying what’s triggering your asthma symptoms
Avoiding inhalant allergens
Focusing on triggers in your home
Recognizing triggers in your workplace
Steering clear of food and drug triggers
Dealing with other conditions that can aggravate your asthma
W ater covers two-thirds of the world’s surface. If you have asthma, it may seem at times that the rest of the planet consists of nothing but asthma triggers. Throughout the world and in virtually every aspect of people’s everyday lives, countless precipitating factors — allergens, irritants, or other medical conditions — can induce asthma symptoms.
Although certain triggers frequently dominate each individual’s asthma, controlling your condition often requires dealing with a host of precipitating factors — an especially common situation if you have allergic asthma, one of the most frequent types of asthma. Allergic asthma is usually associated with allergic rhinitis (hay fever) and/or allergic conjunctivitis (see Chapter 2 for details of allergic asthma).
If the prospect of dealing with a world full of asthma triggers seems daunting, don’t despair. Throughout this chapter, I provide information and tips, based on extensive experience and the latest research findings, that can help you — in consultation with your doctor — implement practical and effective measures for avoiding or reducing exposure to your asthma triggers.
Inhalant allergens, including animal danders, dust mite and cockroach allergens, some mold spores, and certain airborne pollens of grasses, weeds, and trees (see Chapter 10).
Occupational irritants and allergens, found primarily in the workplace, that induce occupational asthma (see the section “Working Out Workplace Exposures,” later in this chapter) or aggravate an already existing form of the disease.
Other irritants that you inhale, such as tobacco smoke, household products, and indoor and outdoor air pollution.
Nonallergic triggers, including exercise and physical stimuli such as variations in air temperature and humidity levels.
Other medical conditions, including rhinitis, sinusitis, gastroesophageal reflux disease (GERD), and viral infections; sensitivities to aspirin, beta-blockers, and other drugs; and sensitivities to food additives — particularly sulfites.
Emotional activities, such as crying, laughing, or even yelling. Although emotions aren’t the direct triggers of asthma symptoms — and clearly asthma isn’t an “emotional problem” — activities associated with emotions (happy or sad) can induce coughing or wheezing in people with pre-existing hyperreactive airways (see Chapter 2), as well as in individuals who don’t have asthma but who may suffer from other respiratory disorders. For example, your friend with a bad cold may say, “Please don’t make me laugh; if I do, I’ll start coughing.”
In order to determine what triggers your asthma symptoms and your sensitivity levels to those triggers, your doctor should take a thorough medical history. Keeping an asthma diary (see Chapter 4) can assist in your doctor’s assessment by providing details of your symptoms and your exposures to potential triggers. Prepare to give your doctor specific information about the respiratory symptoms that you experience.
Figure 5-1: Common asthma triggers. |
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Many asthma patients experience perennial (year-round) symptoms that worsen during particular seasons. Because such a wide range of triggers can contribute to perennial asthma episodes, provide your doctor with a record of the seasonal patterns of your symptoms. Your record contains valuable clues to help your doctor narrow down the factors that affect your condition.
For example, if your asthma consistently worsens during late summer and fall in the eastern parts of the United States, your physician may suspect ragweed or mold as a prime cause of the allergic reactions that aggravate your condition. However, doctors usually advise allergy testing (see Chapter 11 for a complete explanation of allergy testing) to investigate other possible causes and to confirm the diagnosis and determine appropriate treatment.
Nocturnal or nighttime asthma, which often shows up as a nighttime cough, wheezing, and/or shortness of breath, that disturbs your sleep and may require you to use your short-acting adrenergic bronchodilator (see Chapter 14) can often be severe. Allergens in your bedroom, postnasal drip from allergic rhinitis (see Chapter 7), or chronic sinus problems (such as sinusitis; see Chapter 13) often trigger this condition. Other mechanisms that can trigger nocturnal asthma include
GERD
Airway cooling and drying
Increased bronchial airway hyperreactivity
A delayed reaction (known as a late-phase reaction; see Chapter 6) to allergens that you’ve been exposed to previously during the day
The circadian rhythm (also known as diurnal variation ), which is your body’s internal clock, may also affect your asthma, making you more susceptible to symptoms in the early morning hours (around 3 to 5 a.m.). During the late evening and early morning hours, a decrease in plasma levels of adrenal gland (glands above your kidneys) hormones, such as cortisol, a hormone produced by the cortex (outer layer) of the adrenal gland, normally occurs. At the same time, a decrease in plasma epinephrine and an increase in plasma histamine also occur.
Inhalant allergen triggers, also known as aeroallergens, are probably the most familiar asthma precipitants because they’re also associated with allergic rhinitis and similar conditions (see Chapter 7). If you have allergic asthma, reducing your exposure to inhalant allergens is the first and most important step to take — in consultation with your doctor — to manage your condition.
The following list details the most common inhalant allergens to look out for:
Animal allergens. Pet dander, which also may contain traces of saliva, is a potent trigger of symptoms for many people with asthma. Although household dogs and cats are the most common sources of these allergens, all warm-blooded animals, such as horses, rabbits, small rodents, and birds, produce dander — regardless of hair length — that can cause allergic reactions and aggravate your asthma. Urine from these animals is also a source of allergens. Animal dander also serves as a food supply (along with dead human skin scales) for dust mites, as I explain in Chapter 10.
Dust mites. Dust mites abound almost everywhere humans settle, and they thrive especially well in mattresses, carpets, upholstered furniture, bed covers, linens, clothes, and soft toys. Although eradicating these dusty denizens is virtually impossible, you can take practical and effective steps to minimize exposure to the allergens that dust mites produce.
See Chapter 10 for more dirt on dust mites, and Chapter 11 for details on measures to control these creatures.
Many asthmatic patients of inner-city clinics have tested positive for cockroach allergens (through allergy skin testing) but have improved after immunotherapy with cockroach allergen extract. (See Chapter 11 for more information on allergy skin testing and immunotherapy.)
• Exterminate cockroach infestations. During the fumigation process, stay out of your home, and allow it to air out for several hours before re-entering. (This advice applies to anyone, regardless of whether or not you have asthma.)
• Clean your entire home thoroughly after extermination.
• Set roach traps.
• Seal any cracks or other conduits into your home to prevent reinfestation.
• Keep your kitchen clean by washing dishes and cookware promptly and by emptying garbage and recycling containers (including old newspapers) often, and avoid leaving food out.
Mold. The airborne spores that molds (fungi) release in typically damp areas of many homes, particularly from basements, bathrooms, air conditioners, garbage containers, and under carpeting, can trigger allergy and asthma symptoms when you inhale them. Mold can also thrive in leaf piles, compost heaps, cut grass, fertilizer, hay, and barns. Airborne mold spores are more numerous than pollen grains and don’t have a limited season. Depending on where you live, you may receive exposure to airborne spores during many parts of the year, based on levels of humidity.
See Chapter 10 for more moldy matters, including tips on translating mold counts and what you can do to reduce mold exposures.
Pollen. From spring through fall, many varieties of trees, grasses, and weeds release pollens that can trigger symptoms of allergic rhinitis and/or allergic conjunctivitis. These reactions can also affect your asthma, aggravating the underlying airway inflammation.
See Chapter 11 for steps you can take to avoid excessive exposure to pollen, especially during periods of high pollination, and see Chapter 10 for more pollen particulars, including tips on pollen counts.
Tobacco smoke (see the next section)
Fumes and scents from household cleaners, strongly scented soaps, perfumes, glues, and aerosols
Smoke from wood-burning appliances or fireplaces
Fumes from unvented gas, oil, or kerosene stoves
Other sources of indoor air pollution include pollens and mold spores that get inside, especially on windy days when windows and doors are open. These allergenic materials can also infiltrate your home via your clothing and hair. In fact, if you have allergic asthma, you may wake up congested and wheezing in the morning because allergenic materials find their way into your house so easily. (The pollen or mold spores in your hair probably wound up on your pillow, so you spent the night breathing those allergens into your lungs.)
As far as truly irritating irritants go, tobacco smoke is the No.1 indoor air pollutant. Secondhand smoke has been associated with an increase in the following adverse effects: persistent wheezing associated with asthma, hospital admissions for respiratory infections, earlier onset of respiratory allergies, decreased lung function, and even increased incidence of otitis media with effusion (inflammation of the middle ear; see Chapter 13).
The two types of air filtration systems often recommended by doctors for reducing indoor levels of airborne allergens and irritants are
High Efficiency Particulate Arrester (HEPA): These filters are designed to absorb and contain 99.97 percent of all particles larger than 0.3 microns (one-three hundredth the width of a human hair). If the unit truly operates at that level, only 3 out of 10,000 particles get into your indoor environment. Vacuum cleaners and air purifiers with HEPA and ULPA filters (see the next section for more information) can play a vital part in allergy-proofing your home.
Ultra Low Penetration Air (ULPA): This system filters more thoroughly than the HEPA process and is designed to absorb and contain 99.99 percent of all particles larger than 0.12 microns.
Vacuum cleaning is also vital for reducing your exposure to allergens and irritants at home. However, many standard vacuum cleaners only absorb larger particles, and they allow many allergens to escape in the exhaust. This is often why you may experience asthma symptoms after housework: The vacuuming may actually have made matters worse for you by simply stirring up triggering substances that you then inhaled.
Exposures to many types of chemicals and dust in workplace environments can induce different forms of occupational asthma. In many cases, people who have asthma but haven’t yet developed obvious symptoms of the disease may experience asthma episodes for the first time as a result of exposure to occupational triggers. Allergic and nonallergic triggers can play a part in occupational asthma, which may account for as many as 15 percent of all new asthma cases each year in the United States.
Doctors and other healthcare professionals typically associate occupational asthma with exposure to the following workplace triggers:
Industrial irritants: These irritants can include chemicals, fumes, gases, aerosols, paints, smoke, and other substances you primarily find in the workplace. Tobacco smoke in the workplace can cause many asthma symptoms. Likewise, other irritants in the workplace can include perfumes, food odors, and even co-workers who use heavily scented perfumes and colognes.
Occupational allergens: Many occupations involve exposure to or contact with substances made of plant materials, food products, and other items that contain allergenic extracts that can trigger allergic reactions, thus inducing occupational asthma in sensitized people. For example, “Baker’s asthma” can occur in workers who receive constant respiratory exposure to the allergens contained in flour. (Eating the resulting baked food usually doesn’t produce symptoms in these workers, however.) Latex is another common occupational allergen, as I explain in the sidebar “Latex and your lungs.”
Physical stimuli: These stimuli include conditions in your workplace, especially variations in temperature and humidity, such as heat and cold extremes or air that’s especially dry or humid.
In diagnosing a case of occupational asthma, your doctor may first need to assess the following factors:
The pattern of your symptoms. Symptoms that improve when you’re away from work strongly suggest that your problem is indeed work-related.
Your co-workers. Do your co-workers suffer from similar symptoms?
The degree of exposure. Did your first noticeable asthma episode at work occur after a particularly significant exposure, such as a spill of chemicals or other industrial substances?
Latex is increasingly a part of the environment in most medical facilities, due to the need for more aggressive infection control. This rubber compound is found particularly in medical gloves and other medical equipment, such as latex ports in intravenous tubing for administration of fluids and medications.
Because many surgical gloves contain cornstarch powder that’s coated with latex allergen, healthcare workers often inhale airborne allergen latex particles. These exposures can result in allergens from the rubber compounds sensitizing medical personnel. Thus, latex has become one of the most frequent causes of occupational allergy and asthma in the healthcare industry. In addition, patients being treated in medical facilities can also receive exposures and be sensitized to latex.
These exposures can lead to serious symp- toms of allergic rhinitis, asthma, urticaria (hives), angioedema (deep swellings), and, in extreme cases, anaphylaxis (a potentially life-threatening reaction that affects many organs simultaneously).
The allergens in many natural rubber latex products (including condoms and diaphragms) typically cause Type I immediate hypersensitivity IgE-mediated reactions. (I explain this mechanism in Chapter 6.) For this reason, the FDA now requires labeling of all medical devices or packaging containing natural rubber latex. Parents should be aware that latex-sensitive children can be at risk for severe respiratory reactions from rubber balloons.
If you’re at risk for allergic reactions to latex exposure, make sure that any physician who treats you knows this fact so that you can, ideally, receive medical/dental care in a latex-free environment — a setting in which no latex gloves are used and no latex accessories (such as catheters, adhesives, tourniquets, and anesthesia equipment) come into contact with you. Similarly, if your occupation involves contact with latex, find out what you can do to avoid or minimize your exposure to this allergen. In healthcare settings, powder-free latex gloves and non-latex gloves and other medical articles are increasingly becoming available. Using these alternative products can often substantially reduce the risk that you may suffer an allergic reaction to latex.
Additionally, wear a MedicAlert bracelet or pendant to alert medical personnel not to use latex articles in the event that you’re unconscious or unable to communicate during a medical emergency. (The appendix provides information on obtaining these bracelets and pendants.) If you’ve experienced a serious allergic reaction to latex, also ask your doctor whether an emergency epinephrine kit, such as an EpiPen or Twinject, with an injectable dose of epinephrine, is advisable for you.
Some people with asthma also suffer from sensitivities — sometimes potentially life-threatening — to certain foods and medications. In the following sections, I explain the most significant sensitivities that can adversely affect your asthma and what you can do to avoid them.
Approximately 10 percent of asthma patients experience some level of sensitivity to aspirin, aspirin-containing compounds (such as Alka-Seltzer, Anacin, and Excedrin), and nonsteroidal anti-inflammatory drugs (NSAIDs). If your medical history includes nasal polyps and sinusitis in addition to asthma and aspirin sensitivity, use acetaminophen-based products such as Tylenol instead of aspirin or NSAIDs for the relief of common aches and pains.
I strongly advise anyone with this level of sensitivity to wear a MedicAlert bracelet or pendant. This device alerts medical personnel not to administer any medication to which you are sensitive if you’re unconscious or unable to communicate during a medical emergency. See the appendix for more information on MedicAlert bracelets and pendants.
Doctors frequently prescribe oral beta-blocker medications, including Inderal, Lopressor, and Corgard, to treat conditions such as migraine headache, high blood pressure, angina, or hyperthyroidism, and beta-blocker eye drops for eye conditions, such as glaucoma. If you have one of these disorders and you also have asthma, know that taking beta-blockers can worsen your asthma symptoms by blocking the beta 2 -adrenergic receptor sites in your airways that cause bronchodilation, thus making your asthma less responsive to beta 2 -adrenergic (beta 2 -agonist) bronchodilators.
Sulfites are often used as antioxidants to preserve beverages, such as beer and wine, and foods like dried fruit, shrimp, and potatoes. These antioxidants are also often used in salad bars and in guacamole. Exposure to these food additives can trigger severe asthma symptoms — including potentially life-threatening bronchospasm (constriction of the airways) — in as many as 10 percent of people who have severe persistent asthma when these individuals inhale sulfite fumes from treated foods. Severe asthmatics who require long-term treatment with oral corticosteroids (see Chapter 15) are more likely to be sulfite-sensitive and may be especially at risk for severe adverse reactions to these additives.
Some people with asthma develop hypersensitivities to certain foods. However, although certain foods have the potential to cause anaphylaxis, they don’t appear to significantly increase the underlying airway inflammation that’s characteristic of asthma in most patients.
If you’re hungering for details on food allergies, turn to Chapter 8.
In addition to the triggers that I discuss previously in this chapter, certain activities, illnesses, and syndromes can also induce your asthma symptoms or make them worse. Managing these precipitating factors is as vital to effectively controlling your asthma as is avoiding allergens and irritants.
Poorly managing allergic and nonallergic forms of rhinitis can lead to sinusitis. This infection of the sinuses can also aggravate your asthma symptoms, especially if it isn’t responsive to repeated courses of antibiotic treatment. If so, sinus surgery may be necessary to treat sinusitis and reestablish control over asthma symptoms. Studies show that asthma patients who effectively manage their rhinitis and/or sinusitis can significantly improve their asthma symptoms.
Because your respiratory tract is essentially a continuum — or as I like to say, the united airway — treating your nose and sinuses can actually help treat the underlying inflammation that characterizes asthma. In fact, when dealing with serious respiratory diseases such as asthma, doctors increasingly consider it vital to treat the whole patient — not just the patient’s lungs. For more information on dealing with sinusitis and other rhinitis complications, turn to Chapter 13.
Patients who suffer from GERD often burp during and after meals, complain of an acid taste in their mouth, and feel a burning sensation in their throat or chest, symptoms that they typically describe as heartburn or indigestion.
Figure 5-2: GERD occurs when stomach contents spill over into the trachea. |
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GERD is a trigger of asthma symptoms in a large number of asthmatics and is, in particular, a major trigger of adult-onset asthma (see Chapter 2) in patients whose asthma symptoms (coughing, wheezing, shortness of breath) aren’t usually associated with allergic triggers. If you’re asthmatic, the flow of acidic digestive contents into your respiratory airways can make your underlying airway inflammation worse. GERD, with or without inhalation of stomach contents, has also been associated with increased bronchospasm and chronic cough due to irritation of the esophagus. Conversely, when asthma is active, it can also aggravate GERD, and some of the drugs used to treat asthma, such as long-acting beta 2 -adrenergic bronchodilators and oral theophylline (see Chapter 15 for details on long-term asthma medications), can also worsen GERD symptoms.
Avoid eating or drinking within three hours of going to bed.
Avoid heavy meals and minimize dietary fat. Also, try to eat several small meals over the course of the day instead of fewer, larger meals.
Eliminate or cut down on the consumption of chocolate, peppermint, alcoholic beverages, coffee, tea, and colas and carbonated beverages.
Avoid or reduce smoking and the use of any tobacco products.
Try elevating the head of your bed, by using 6- to 8-inch blocks, so that your stomach contents are less likely to rise to the point that you can inhale them while sleeping. Adding pillows under your head can also be of some benefit.
To control the digestive problems that result from your GERD symptoms, use appropriate over-the-counter (OTC) products, including Zantac, Tagamet, Axid, Prilosec OTC, and Pepcid AC. Your physician may also prescribe other medications, such as Nexium, Protonix, Aciphex, and Prevacid, which decrease gastric (stomach) acid secretion.
Viral respiratory infections, such as the common cold or flu, can aggravate airway inflammation and trigger asthma symptoms. Asthmatic children under age 10 are particularly prone to asthma symptoms precipitated by rhinovirus infections (upper respiratory infections, usually referred to as the common cold).
Rhinovirus infections cause bronchial hyperreactivity and promote allergic inflammation, leading to increased asthma symptoms. For infants and toddlers, viral infections of all types are the most frequent cause of severe asthma episodes because infants and younger children have smaller airways that are often more susceptible to bronchial obstruction. These infections are also the most frequent cause of episodes in adults, especially those with nonallergic (intrinsic) asthma.
Consider the following measures when dealing with viral infections:
If your have persistent asthma, ask your doctor about receiving an annual flu vaccine to reduce the risk of suffering from an influenza respiratory infection that could aggravate your asthma symptoms.
Antiviral medications can help you avoid coming down with influenza even when you’ve had a flu shot. Flu vaccines consist of the World Health Organization’s (WHO) best guess of the viruses from the preceding year that may cause the flu during next year’s winter season. However, the WHO’s predictions aren’t always accurate. As a result, a flu shot may not fully protect you against the viral strains that cause the current year’s flu epidemic, thus making antiviral medications extremely beneficial.