^*Halsted had known Welch well in New York; both of them were trying to apply science to medicine. But Halsted began studying cocaine and became addicted. His life collapsed and he moved to Baltimore to be close to Welch. Once Halsted ended his addiction, Welch gave him a chance at the Hopkins, where he linked surgery to physiological research and became the most influential surgeon in the country and arguably the world. Halsted did marry, but he was eccentric and erratic and became addicted to morphine. It was unclear if Welch knew of this addiction.