CHAPTER 8

NAVIGATING YOUR TRANSITION TO BURNING FAT

Now that you’ve modified your diet to follow the fat-burning eating plan, your body will need to make the switch from burning glucose for fuel to burning fat. Be patient. This is a multistep process that can take anywhere from a few days to a few months, depending on your current health, your commitment to your macronutrient targets, and your metabolic flexibility as you begin to burn fat.

MMT is highly customizable to you and your body, and it may take a while to find the foods and practices that enable you to become fully fat adapted—I’ll go into more detail on this in the next chapter. The aim of this chapter is to help you make the smoothest transition you can and get ahead of any possible challenges before they become big enough to potentially derail you.

WHATS HAPPENING WITH YOUR METABOLISM

Before you begin to burn fat, you must first use up the glycogen that is now stored in your skeletal muscles and your liver. In their book The Art and Science of Low Carbohydrate Performance, researchers Jeff Volek, Ph.D. and R.D., and Stephen Phinney, M.D. and Ph.D., estimate that glycogen stores in the average person top out at somewhere between 400 and 500 grams, of which 100 grams are stored in the liver. That translates to somewhere between 1,600 and 2,000 calories. If you have a lot of muscle mass and have eaten a high-carb diet, your stores may be higher than that.

Each gram of glycogen is stored with 3 to 4 grams of water, which means that as your stores are depleted, you will also lose this water weight, typically almost immediately after you begin restricting your carb intake. This is great news if one of your goals is weight loss.

As you can probably guess, burning 1,600 to 2,000 calories will only take a day or two—less time if you’re active and more time if you’re sedentary. But making the transition to burning fat isn’t as simple as running through your glycogen. You also have to keep insulin levels low because insulin inhibits lipase, the hormone-sensitive enzyme that breaks down fat. Not only that, but you have to keep to this lower level for a couple of weeks to several months to fully activate your body’s fat-burning system. Longer times are required for those who have profound insulin and leptin receptor resistance, especially if they are not using water fasts (covered as On-ramp #3 in Chapter 7 and again in more detail in Chapter 10).

Initially, your body will likely alternate between burning ketones, fatty acid, and glucose, which your liver can manufacture from excess protein, the breakdown of muscle tissue, or the freeing up of glycerol, which forms the backbone of triglycerides.

When you run out of glycogen, you may experience cravings for carbs and sweets, or feel hungry, because your body isn’t particularly adept at burning fat for fuel yet. This temporary energy deficit may tempt you to sneak a few more carbs here and there, or to overeat protein, but this will backfire because it will keep you in this transition longer by supplying more glucose and more insulin. This will only delay the shift to burning fat.

As your glycogen stores become depleted, your liver takes on a larger role in maintaining a healthy level of blood glucose (“glucose homeostasis”). Before you started eating a high-fat diet, insulin and another pancreatic signaling hormone called glucagon were primarily responsible for tightly regulating your blood sugar levels. Now metabolic sensors in your liver are assuming that role, and they will at first seek to restore glycogen through the production of glucose, either from protein you’ve consumed or by breaking down skeletal muscle and/or using glycerol if you are consuming enough fat.

When your glucose levels are elevated, this will impair lipase from burning fat for fuel. It’s only when you eliminate the interference of high glucose—either from dietary sources or from manufacture in the liver (gluconeogenesis)—that you begin to ramp up your fat burning. The longer and more consistently you restrict your intake of carbs while also limiting protein to 1 gram per kilogram of lean body mass or lower, the more efficient your liver will be as it figures out how to make this switch to burning fat for fuel.

The more compliant you are in the beginning of MMT, by really sticking to your macronutrient ratios and logging all the food you eat, the smoother this transition will be. Initially, even seemingly insignificant amounts of carbs will tend to cause a rise in your glucose, which will impair your fat burning. If you binge on carbs in the transition phase, you’ll replenish your glycogen stores and lengthen the time it takes for you to shift to burning fat as your primary fuel.

As a general rule, the younger and healthier you are, the faster you can move through this transition. A school-age child can make the switch in 24 to 36 hours. While kids can transition much quicker, this does not mean they should be on this program unless they have intractable seizures or cancer.

Folks in their 20s and 30s have the easiest time of it, while people in their 40s and 50s will generally face a little more of a challenge (unless you are already fit and following a whole-foods, Paleo-like diet). Those in their 60s and 70s will likely need to be very committed to make the switch. But if this is you, don’t be discouraged; I started MMT at 61 and it only took a few weeks to shift to fat-burning mode.

If you are in your 80s or older, you can absolutely adopt the diet—it will likely just take a bit longer. Elderly individuals need to be monitored very carefully to prevent muscle loss (sarcopenia). The bottom line is that the sooner you get on board with MMT, the more easily you’ll be able to sustain it and continue to enjoy the health benefits as you get older.

USE YOUR BLOOD GLUCOSE READINGS TO GAUGE YOUR PROGRESS

Remember that you want to test your blood glucose levels two to three times a day: when you first wake up, just before you eat your first meal of the day, and just before you go to bed. During this transitional period, your glucose readings may show great variation, but erratic readings may be due to the fact that your meter is only a screening tool; just redo the test (see below). Even if the results are initially hard to interpret, as you continue with the eating plan you will see your readings settle down into a more predictable pattern.

Your blood glucose readings provide powerful feedback on how appropriate your food choices are: if your glucose numbers are high, it suggests that you’ve eaten too many net carbs and/or too much protein, although there can be other factors at work (see the sidebar on the next page for those).

While you will likely see spikes and dips in the beginning, you will get more adept at choosing foods that keep you in the fat-burning zone, and you will start to see your early-morning and late-night readings smoothing out over time. Even then, expect the occasional spike. Just remember: your focus is on the trend over the course of several days, or even weeks, and your reward is watching your glucose numbers go down and become more stable. That means your insulin isn’t working as hard either.

Reasons Why You May Be Getting a High Glucose Reading

It can be alarming to measure your blood glucose levels and see some unexpectedly high readings. Here are some common triggers that may explain them:

WHEN YOU EAT MATTERS

A way to enhance your transition to fat burning is to begin to experiment with regular periods of fasting. There are many ways to do this, and many powerful benefits to reap, all of which I cover in Chapter 10. For the time being, aim to finish your last meal at least three hours before bedtime, and then wait as long as possible before eating breakfast the next day. This will help you ease into my favorite form of intermittent fasting, which I call Peak Fasting.

THE SIZE OF YOUR MEAL MATTERS

Ideally, it is best to time your biggest meal for before your most active period of the day so your muscles—which remain responsive to glucose even when you’re fat burning—will remove most of the extra glucose and insulin from your blood before they have the chance to disrupt your new fat-burning metabolism. Also ideally, you’d divide this largest meal in half and eat the second half 60 to 90 minutes after the first half, as this results in less nitrogen stress on your kidneys.

You also want to spread your protein consumption out over the day, limiting your protein at a given meal to about 15 grams. This makes it less likely that an excess of amino acids from protein will be converted into glucose by the liver, and it will also ease the detoxification burden on your kidneys. This is especially important if you already have some kidney insufficiency, with a serum creatinine level above 1. If this sounds like a low intake of protein to you, remember that excess amino acids are also a powerful stimulus to activate mTOR. (If you’d like a refresher on this information, refer back to Chapter 3.)

Especially during this transitional period, plan on having at least one or two high-fat snacks during the day. This will help tamp down any hunger or cravings and keep you feeling full and satisfied. (See the sidebar for several high-fat snack suggestions.)

COMMON SYMPTOMS EXPERIENCED DURING THE TRANSITION TO FAT BURNING AND THEIR REMEDIES

As you make the switch to burning fat and your body relearns how to burn fat instead of glucose for fuel, it is normal to go through a period where you experience one or a couple of common symptoms. You can manage the intensity of these symptoms by deciding how quickly you’ll change your diet, but you can’t totally avoid all of them: your body is learning a new way to fuel itself, so expect a glitch or two as it finds its way.

Here are the most common symptoms and simple ways to ward them off:

NUTRIENT-DENSE SMOOTHIE RECIPE

Makes 1 smoothie

I love using smoothies to take in a lot of nutrients in one tasty swoop. Below are the ingredients I use to make my twice-daily smoothie, which is low carb, high fat, and moderate protein. I typically include everything on this list, although it does fluctuate depending on what I have available. Don’t be intimidated by the long list of ingredients. Try to incorporate everything in the foundation, and add optional add-ins as you see fit.

Foundation:

1 teaspoon to 1 tablespoon MCT oil (depending on tolerance)

½ to 1 avocado (depending on preference)

1 scoop organic greens powder

1 tablespoon organic whole-husk psyllium

1 to 3 ounces frozen organic fruit

1 to 3 droppers full of stevia (to taste)

2 tablespoons raw organic cocoa butter

1 tablespoon organic chia seeds

1 tablespoon flax seeds (soaked overnight)

Optional add-ins:

1 tablespoon black cumin or black sesame seeds (soaked overnight)

1 teaspoon hawthorn berries

½ teaspoon pau d’arco powder

½ teaspoon ground organic egg shells

1 teaspoon food-grade diatomaceous earth

1 teaspoon trumpet mushroom powder

Directions:

Combine everything in a blender—I use a one-quart NutriBullet. Fill with water nearly to the top. Blend for approximately two minutes. Enjoy!

MANAGING YOUR EMOTIONS DURING TRANSITION

As is true with any significant change, if you are feeling hopeful and confident, you will be better equipped to make a smooth transition to a fat-burning diet. Taking charge of your health in this way can be quite a dramatic shift from how you’ve dealt with health issues in the past: by simply responding to orders from your doctor. You may feel unqualified to take on this responsibility. Or, you may feel reluctant to give up bread, cookies, chips, or even foods that you once thought were healthy. Or, you may be facing a frightening medical diagnosis that has left you feeling overwhelmed or even depressed.

If you are considering this eating plan, or even reading this book, because someone who cares about you is pushing you to try it, take my advice—wait. If you make these changes simply to please someone else, you are less likely to truly commit to the eating plan. Without commitment, you are more likely to quit at the first real challenge and blame the diet, when in actuality you simply weren’t ready to embrace these changes. If that’s the case, let the ideas that I’m presenting in this book continue to percolate in your mind. I hope that someday in the near future you’ll feel more ready to embark on this adventure.

Another peril in starting MMT while in a state of emotional turmoil is that you are more likely to turn to food for comfort or you will be easily discouraged by any little bump in the road—one high glucose reading may leave you with doubts that undermine your confidence and commitment.

Transition Tip: It’s normal to have some cravings when you first start MMT. These are typically easily to deal with if you are prepared with some high-fat snacks (see for ideas). If you are craving comfort food, however, no number of fat bombs will satisfy you. Then you need to ask yourself the question, What else can I do that will make me feel loved and cared for? Turning back to high-carb foods at this juncture will only prolong or derail your transition, and ultimately that’s not a very loving thing to do to yourself.

Spend some time thinking about why you are making these changes. Think beyond weight loss and include improvements you want to see in your health. Write these down so you can refer back to them in moments when you’re tempted to revert to old eating habits. Be specific so you can honestly assess the progress you’ve made.

Another powerful strategy is to visualize yourself healthy the way you want to be and attach as many positive emotions to that image as you can. Write this down and regularly reflect and meditate on this state. It is especially important to seek to experience as many of the positive emotions connected to achieving this goal as possible; this will radically increase your likelihood of attaining it.

I am also a strong advocate of the Emotional Freedom Technique (EFT) as a powerful tool to mediate emotional stressors. EFT is a DIY, needleless form of acupuncture that entails tapping on specific points on your face, arms, and hands while repeating positive affirmations. I’ve written about it extensively at eft.mercola.com. If you run into emotional roadblocks along your MMT journey, I highly recommend exploring EFT. You can do it on your own, or find a certified practitioner; the information I’ve compiled on my website will provide you with resources and help you decide on the approach that suits you best.

EXERCISEBUT KEEP IT MODERATE

As your body adjusts to burning fat instead of glucose as your primary fuel, it’s best if you keep to moderate levels of activity. Strenuous exercise at this time can interfere with your ability to keep glucose low by breaking down muscle tissue, which is then recycled into glucose by the liver.

One way to determine if your workout was too strenuous is to measure your blood glucose before and after your exercise session. If it’s higher than 10 to 20 mg/dL after your workout, you know that you’ve triggered the liver to manufacture more glucose. If this happens, go for a 30-minute walk (or swim or take a gentle bike ride) to allow your muscles to take up that glucose. This is preferable to leaving it in your bloodstream, where it can cause an uptick in insulin.

Walking is a fantastic form of exercise for nearly everyone. In addition to regulating your blood sugar, it reduces cytokines, signaling molecules often associated with inflammation. Walking improves mood and self-esteem, and just as importantly, the more time you spend walking, the less time you spend sitting—which is a risk factor for nearly every major chronic disease. You don’t need much to reap the benefits. Multiple studies show that just a few hours of walking a week lowers the risk of breast cancer.

Most days, I walk barefoot on the beach for one to three hours and use the time to clear my thoughts, make phone calls, and go through the stack of books and journal articles stored on my Kindle—all this while deriving the health benefits of sun exposure (wearing shorts and no shirt) and grounding. By being in direct connection with the earth, you establish an electrical connection that provides positive ions stored in the ground, which can then neutralize free radicals in the body (for more information on this, please see my previous book, Effortless Healing). I don’t consider this walk to be exercise—rather, I view it as pleasurable movement with the added benefit of reducing the risk of obesity, stroke, coronary heart disease, breast and colon cancer, type 2 diabetes, and osteoporosis while also improving mental health, blood pressure, and blood lipid profiles.1

I am also a strong proponent of high-intensity interval training, so I understand if you are reading this section and thinking, No way am I only taking walks for exercise. Remember: keeping workouts light is only temporary. Once you are through the transition process, it is likely that you will be able to return to your high-intensity workouts.

For some of Miriam’s clients, maintaining high-intensity exercise despite their disease and new eating pattern is a quality-of-life issue: the thought of backing off, even if it is temporary, is enough to keep them from fully committing to needed changes. She counsels them that there are still many metabolic advantages to adopting a high-fat diet, but they need to understand that their intensive workouts can slow or even derail their progress unless it is very carefully managed and monitored. (Ketone supplementation and Peak Fasting are particularly valuable to athletes.) It is ultimately your decision to make—but you want to make it with your eyes open. The book The Art and Science of Low-Carb Performance is an extremely valuable guide if both a high-fat diet and high-intensity exercise are important to you.

KNOW THE CHALLENGES

After working with hundreds of clients, Miriam is acutely aware of the most common challenges people face when adopting a fat-burning eating plan. Be proactive and stand ready to face them head on and you will lessen the likelihood that any of these common issues will derail your efforts or cause your commitment to waver.

Deciding how long you want to continue with the MMT eating plan depends a lot on what you expect to gain. If you have cancer, you may always want to eat this way, especially if it results in an amazing and unexpected response. Otherwise, you can basically remain on the program over the long term by following the principles of feast-famine cycling, which I cover in Chapter 10.

If you’re committed to the idea of MMT but are having a rough time with these or other common challenges, or any other aspect of the eating plan, I strongly recommend you seek help from a health coach or a nutritionist who is trained in supporting high-fat diets. A professional can help you troubleshoot your issues by asking questions about what’s working and what’s not and then looking at your food diary and data such as your glucose readings and making some targeted suggestions. in combination with the overall support they provide, this extra bit of coaching can make all the difference between success and failure. MMT is such a powerful plan that you want to make sure you haven’t given up on it too soon, especially if the problem had an easy fix.

Often, people who seek out Miriam’s help do so because they are feeling overwhelmed by all the changes. But if they already understand food basics and are comfortable with preparing meals from scratch, quite often she can get them past their trouble spots and help them feel much more confident in only three or four hours. It’s not a big investment, but the payoff is huge. Another plus is that most people with extensive experience here offer their services online or through phone- or web-based video consultations.

To that end, Miriam and I have worked with Certified Nutrition Specialists to provide a training and certification course for physicians and nutritionists. You can go to their site (www.NutritionSpecialists.org) to find a consultant.

Using MMT to Optimize Conventional Breast Cancer Treatment

In July 2015, Denise was in Hawaii, on vacation with college friends, celebrating their 60th birthdays. Drying off at the beach, she noticed what felt like a bruise on her left breast. She wasn’t terribly concerned—she and her friends had been snorkeling, boogie boarding, and hiking volcanoes. Surely she’d just gotten bumped and hadn’t noticed.

Fast forward to August 2016, when Denise learned she had Stage IIIA lobular breast cancer. She and her husband immediately launched into intense research mode, reading up on treatment strategies, cutting-edge breakthroughs, recurrence and survival statistics: information they would need for the many complicated choices a breast cancer patient must make. After a few weeks, they began to close in on a plan that they believed would maximize Denise’s odds of survival.

By September, Denise was receiving a hormone inhibitor plus a chemo pill, therapy designed to shrink the tumor and suppress the hormones that allow some breast cancer cells to thrive. She also decided to adopt a ketogenic diet in an effort to both deny cancer its primary fuel source and to lose weight. At five feet five, Denise weighed 223 pounds. Her research had shown her that fat itself, especially belly fat, was her primary source of cancer-promoting hormones. She’d read the scary fact that women who did not get their weight down to a healthy range had a much higher rate of recurrence and earlier death.

Denise started working with Miriam Kalamian to develop a sensible plan for managing breast cancer. In her case, that also meant limiting estrogen-heavy dairy products, so Denise adopted a reduced-calorie, light-dairy ketogenic diet.

As Denise puts it, “I love carbs, but when faced with my own mortality, I love my husband and kids more. And I need to be here to take care of my mother, who has Alzheimer’s.” She adapted easily to her new plan: eggs for breakfast, avocado bacon boats for lunch, five squares of Lily’s dark chocolate (sweetened with stevia) for a snack, and salad, sautéed mushrooms, and pick-your-protein for dinner. She rounded that out with blackberries or almonds and coconut for dessert. At the movies she’d have a Cocommune bar, which is “very close to an Almond Joy,” she reports. At restaurants she ordered salmon, broccoli, and a salad. Instead of mashed potatoes at Thanksgiving, she served mashed cauliflower with lots of butter and it was a hit with her guests.

Denise added, “I got on with my life and believe that I’m truly, actually lengthening it with my food choices. I’ve dropped seventy-five pounds. I feel healthy and energetic.” Even while on chemo, she restarted dance and aerobic classes. Her sleep pattern improved, and as she notes, “I look pretty dang good. And my husband jokes, ‘Fighting cancer seems to agree with you.’”

No stranger to dieting, Denise was pleased to discover that cravings and hunger pangs, a bane of her past efforts at weight loss, disappeared in about 10 days, and after that, sticking to the plan was fairly easy. She does caution, “If you cheat, you’ve got to go through those ten very hard days again. Not worth it.”

With few exceptions, Denise kept to her plan through a round of radiation in April and May of 2016, adding in intermittent fasting with the aim of reducing the side effects of treatment and increasing the cancer’s sensitivity to radiation. She did so by not eating for 16 hours before each treatment. She drank a lot of water to stay hydrated but kept her food intake to a 5-hour window in the afternoon.

After drug therapy, a diet upgrade, a mastectomy, and radiation, Denise is considered cancer free. But, as with all breast cancer survivors, her recurrence risk is considered high, so Denise is likely to continue with a hormone inhibitor for five to seven years. She also plans on staying on the ketogenic diet for at least that long. Her logic: “While I’m starving any cancer remnants of hormones, why would I not starve them of carbs and sugar as well? Preventative maintenance seems crucial. I do not want to have to go through this again!” Denise’s efforts have succeeded on so many fronts. Why wouldn’t she want to stay with a plan that’s working for her?