Guidelines for equianalgesic dosing of commonly used analgesics are presented in the following table. The dosages are approximate to 10 mg of morphine intramuscularly. These guidelines are for the management of acute pain in the opioid-naïve pt. Dosages may vary for the opioid-tolerant pt and for the management of chronic pain. Dosing adjustments for renal or hepatic insufficiency may also be necessary. Clinical response is the criterion that must be applied for each pt with titration to desired response.
| Name | Equianalgesic Oral Dose | Equianalgesic Parenteral Dose (IV, IM, SQ) |
| Codeine | 200 mg | 100–130 mg |
| Fentanyl | Not available | 0.1 mg (100 mcg) |
| Hydrocodone | 30–45 mg | Not available |
| Hydromorphone (Dilaudid) | 7.5–8 mg | 1.5–2 mg |
| Hydromorphone (Dilaudid) (Controlled-Release) | 7.5 mg | N/A |
| Meperidine (Demerol) | 300 mg | 75 mg |
| Methadone (Dolophine) | 10–20 mg | 10 mg |
| Morphine | 30 mg | 10 mg |
| Oxycodone (OxyContin) | 20–30 mg | Not available |
| Oxymorphone | 10 mg | 1 mg |
| Oxymorphone (Extended-Release) | 10 mg | N/A |