ENDNOTES

Introduction

1.      U.S. Environmental Protection Agency. Drinking water contaminants—standards and regulations. Updated January 6, 2016. http://water.epa.gov/drink/contaminants/basicinformation/mercury.cfm; World Health Organization. Mercury and health. Updated January 2016. http://www.who.int/mediacentre/factsheets/fs361/en

2.      Knott L. Tungsten poisoning. Patient. 2014. http://patient.info/doctor/tungsten-poisoning; Jaslow R. Exposure to tungsten metals found in phones, computers linked to strokes. CBS News. November 13, 2013. http://www.cbsnews.com/news/tungsten-metals-found-in-phones-computers-linked-to-strokes

3.      Peeples L. Lead poisoning threshold lowered by CDC, five times more children now considered at risk. The Huffington Post. May 16, 2012. http://www.huffingtonpost.com/2012/05/16/lead-poisoning-cdc_n_1522448.html

4.      World Health Organization. Arsenic. December 2012. http://www.who.int/mediacentre/factsheets/fs372/en/; U.S. Environmental Protection Agency. Chemical contaminant rules. November 9, 2015. http://water.epa.gov/lawsregs/rulesregs/sdwa/arsenic/index.cfm

5.      U.S. Environmental Protection Agency. Cadmium compounds (A). September 9, 2015. http://www.epa.gov/ttnatw01/hlthef/cadmium.html; Agency for Toxic Substances and Disease Registry. Cadmium toxicity: what health effects are associated with acute high-dose cadmium exposure? May 12, 2008. http://www.atsdr.cdc.gov/csem/csem.asp?csem=6&po=11

6.      Wong E. China to reward cities and regions making progress on air pollution. The New York Times. February 13, 2014. http://www.nytimes.com/2014/02/14/world/asia/china-to-reward-localities-for-improving-air-quality.html

7.      Julshamn K, Maage A, Noril HS, et. al. Determination of arsenic, cadmium, mercury, and lead in foods by pressure digestion and inductively coupled plasma/mass spectrometry: first action 2013.06. 2013. National Center for Biotechnology Information. http://www.ncbi.nlm.nih.gov/pubmed/24282954

Part 1: Everything You Need to Know About Toxic Elements

8.      U.S. Center for Disease Control and Prevention. Fourth national report on human exposure to environmental chemicals. 2009. Updated 2013. http://www.cdc.gov/exposurereport/pdf/FourthReport_UpdatedTables_Sep2013.pdf#page=1&zoom=auto,0,800

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13.    Reichard J, Schnekenburger M, & Puga A. Long-term low-dose arsenic exposure induces loss of DNA methylation. Biochemical and Biophysical Research Communications. 2007. 352(1):188–92. PMID: 17107663. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/17107663

14.    Ibid.

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Heavy Metals: Arsenic

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28.    Ravenscroft P. Predicting the global distribution of arsenic pollution in groundwater. Royal Geographical Society Annual International Conference. 2007. Department of Geography, University of Cambridge. http://www.geog.cam.ac.uk/research/projects/arsenic/symposium/S1.2_P_Ravenscroft.pdf

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33.    Reichard J, Schnekenburger M, & Puga A. Long term low-dose arsenic exposure induces loss of DNA methylation. Biochemical and Biophysical Research Communications. 2007. 352(1):188–92. PMID:17107663. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/17107663

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56.    U.S. Food and Drug Administration. Questions and answers regarding 3-nitro (roxarsone). Updated April 1, 2015. http://www.fda.gov/AnimalVeterinary/SafetyHealth/ProductSafetyInformation/ucm258313.htm

57.    Lasky T, Sun W, Kadry A, et al. Mean total arsenic concentrations in chicken 1989–2000 and estimated exposures for consumers of chicken. Environmental Health Perspectives. 2004. 112(1):18–21. PMCID:PMC1241791. PubMed. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241791/pdf/ehp0112-000018.pdf

58.    U.S. Food and Drug Administration. Questions and answers regarding 3-Nitro (roxarsone). April 1, 2015. http://www.fda.gov/AnimalVeterinary/SafetyHealth/ProductSafetyInformation/ucm258313.htm#uses_of_arsenic-based_animal_drugs

59.    Nachman KE, Baron PA, Raber G, et al. Roxarsone, inorganic arsenic, and other arsenic species in chicken: a U.S.-based market basket sample. Environmental Health Perspectives. 2013. Johns Hopkins Center for a Livable Future. http://www.jhsph.edu/research/centers-and-institutes/johns-hopkins-center-for-a-livable-future/research/clf_publications/pub_rep_desc/arsenic_chicken.html

60.    Nachman KE, Baron PA, Raber G, et al. Arsenic levels in chicken: Nachman et al. respond. Environmental Health Perspectives. 2013. 121(9):a267–a268. PMCID:PMC3764093. PubMed. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764093

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Heavy Metals: Mercury

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86.    Ibid.

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117.  Stanhope KL & Havel PJ. Endocrine and metabolic effects of consuming beverages sweetened with fructose, glucose, sucrose, or high fructose corn syrup. American Journal of Clinical Nutrition. December 2008. 88(6):1733S–1737S. PMCID:3037017. PubMed. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037017

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129.  Institute for Agriculture and Trade Policy. Much high fructose corn syrup contaminated with mercury, new study finds. January 25, 2009. http://www.iatp.org/documents/much-high-fructose-corn-syrup-contaminated-with-mercury-new-study-finds

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216.  Senapati SK, Dey S, Dwivedi SK, et al. Effect of garlic (Allium sativum L.) extract on tissue lead level in rats. Journal of Ethnopharmacology. 2001. 76(3):229–32. PMID:11448543. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/11448543

217.  Pourjafar M, Aghbolaghi PA, & Shakhse-Niaie M. Effect of garlic along with lead acetate administration on lead burden of some tissues in mice. Pakistan Journal of Biological Sciences. 2007. 10(16):2772–4. PMID:19070102. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/19070102

218.  Chandrasekaran VR, Hsu DZ, & Liu MY. Beneficial effect of sesame oil on heavy metal toxicity. Journal of Parenteral and Enteral Nutrition. 2013. 38(2):179–85. PMID: 23744838. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/23744838

219.  Liao Y, Zhang J, Jin Y, et al. Therapeutic potentials of combined use of DMSA with calcium and ascorbic acid in the treatment of mild to moderately lead intoxicated mice. Biometals. 2008. 21(1):1–8. PMID:17287888. Science.NaturalNews. http://science.naturalnews.com/pubmed/17287888.html

220.  Blaucok-Busch E, Amin OR, Dessoki HH, et al. Efficacy of DMSA therapy in a sample of Arab children with autistic spectrum disorder. Maedica. 2012. 7(3):214–21. PMID:23400264. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/23400264

221.  Bradberry S, Sheehan T, & Vale A. Use of oral dimercaptosuccinic acid (succimer) in adult patients with inorganic lead poisoning. Monthly Journal of the Association of Physicians. 2009. 102(10):721–32. PMID:19700440. Science.NaturalNews. http://science.naturalnews.com/pubmed/19700440.html

Heavy Metals: Cadmium

222.  Mortvedt JJ. Heavy metal contaminants in inorganic and organic fertilizers. Fertilizer Research. 1996. 43:55–61. Springer Link. http://link.springer.com/article/10.1007/BF00747683#page-1

223.  Dorris J, Atieh BH, & Gupta RC. Cadmium uptake by radishes from soil contaminated with nickel cadmium batteries: toxicity and safety considerations. Toxicology Mechanisms and Methods. 2002. 12(4):265–76. PMID:20021168. Science.Naturalnews.com. http://science.naturalnews.com/pubmed/20021168.html

224.  Mortvedt JJ. Heavy metal contaminants in inorganic and organic fertilizers. Fertilizer Research. 1996. 43:55–61. Springer Link. http://link.springer.com/article/10.1007/BF00747683#page-1

225.  Frontline. Dr. Arjun Srinivasan: we’ve reached “the end of antibiotics, period.” Public Broadcasting Station. 2013. http://www.pbs.org/wgbh/pages/frontline/health-science-technology/hunting-the-nightmare-bacteria/dr-arjun-srinivasan-weve-reached-the-end-of-antibiotics-period

226.  U.S. Food and Drug Administration Center for Veterinary Medicine. 2009 summary report on antimicrobials sold or distributed for use in food-producing animals. December 9, 2010. http://www.fda.gov/downloads/ForIndustry/UserFees/AnimalDrugUserFeeActADUFA/UCM231851.pdf

227.  Loglisci R. New FDA numbers reveal food animals consume lion’s share of antibiotics. 2010. Johns Hopkins Center for a Livable Future. http://www.livablefutureblog.com/2010/12/new-fda-numbers-reveal-food-animals-consume-lion%E2%80%99s-share-of-antibiotics

228.  Sapkota AR, Curriero FC, Gibson KE, et al. Antibiotic-resistant enterococci and fecal indicators in surface water and groundwater impacted by a concentrated swine feeding operation. Environmental Health Perspectives. 2007. 115(7):1040–1045. PMCID:PMC1913567. PubMed. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1913567

229.  Wan Y, Bao Y, & Zhou Q. Simultaneous adsorption and desorption of cadmium and tetracycline on cinnamon soil. Chemosphere. 2010. 80(7):807–12. PMID:20510430. Science.Naturalnews. http://science.naturalnews.com/pubmed/20510430.html

230.  Kitana N & Callard IP. Effect of cadmium on gonadal development in freshwater turtle (Trachemys scripta, Chrysemys picta) embryos. Journal of Environmental Science and Health. 2008. 43(3):262–71. PMID: 18205057. Science.NaturalNews. http://science.naturalnews.com/pubmed/18205057.html

231.  Luca G, Lilli C, Bellucci C, et al. Toxicity of cadmium on Sertoli cell functional competence: an in vitro study. Journal of Biological Regulators and Homeostatic Agents. 2013. 27(3):805–816. PMID: 24152845. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/24152845

232.  Kazantzis G. Cadmium, osteoporosis and calcium metabolism. Biometals. 2004. 17(5):495–8. PMID:15688852. Science.NaturalNews. http://science.naturalnews.com/pubmed/15688852.html

233.  Tsuchiya K. Causation of ouch-ouch disease (Itai-Itai Byõ)—an introductory review. I. Nature of the disease. The Keio Journal of Medicine. 1969. 18(4):181–94. PMID: 4915215. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/4915215

234.  Paniagua-Castro N, Escalona-Cardoso G, Hernández-Navarro D, et al. Spirulina (arthrospira) protects against cadmium induced teratogenic damage in mice. Journal of Medicinal Food. 2011. 14(4):398–404. PMID:21254891. Science.Naturalnews. http://science.naturalnews.com/pubmed/21254891.html

Heavy Metals: Aluminum

235.  Hetherington LE. World mineral production: 2001–2005. British Geological Survey. 2007. ISBN: 978-0-85272-592-4. Keyworth, Nottingham: British Geological Survey.

236.  U.S. Environmental Protection Agency. Acid rain. Updated December 4, 2012. https://www.epa.gov/acidrain/effects-acid-rain

237.  Sayer J. Is eating and injecting aluminum safe as our regulators say? Green Med Info. May 27, 2012. http://www.greenmedinfo.com/blog/eating-aluminum-it-safe-our-regulators-say

238.  European Food Safety Authority. Scientific opinion of the panel on food additives, flavourings, processing aids and food contact materials (AFC). The EFSA Journal. 2008. 754:2–34. http://www.efsa.europa.eu/en/efsajournal/doc/754.pdf

239.  Ibid.

240.  Chuchu N, Patel B, Sebastian B, et al. The aluminium content of infant formulas remains too high. BMC Pediatrics. 2013. 13:162. http://www.biomedcentral.com/content/pdf/1471-2431-13-162.pdf

241.  Jefferson Lab. The element aluminum. Jefferson Lab Science Education. http://education.jlab.org/itselemental/ele013.html

242.  Helmenstine, AM. Is alum safe to eat or use? Food and Cooking Chemistry FAQs. About.com. Updated February 16, 2016. http://chemistry.about.com/od/foodchemistryfaqs/f/Is-Alum-Safe.htm

243.  Wise Geek. What are the pros and cons of alum for pickling? Accessed February 23, 2016. http://www.wisegeek.com/what-are-the-pros-and-cons-of-alum-for-pickling.htm

244.  European Food Safety Authority. Scientific opinion of the panel on food additives, flavourings, processing aids and food contact materials (AFC). The EFSA Journal. 2008. 754:2–34. http://www.efsa.europa.eu/en/efsajournal/doc/754.pdf

245.  Ibid.

246.  Thompson J. Aluminum chelation. The Health Sciences Institute. HSI Online. June 25, 2003. http://hsionline.com/2003/06/25/aluminum-chelation

247.  Schaeffer G, Fontès F, le Breton E, et al. The dangers of certain mineral baking-powders based on alum, when used for human nutrition. Journal of Hygiene. 1928. 28(1):92–99. PMCID:PMC2167687. PubMed. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2167687

248.  Herzog P. Effect of antacids on mineral metabolism. Zeitschrift fur Gastroenterologie. 1983. Suppl:117–26. PMID: 6858403. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/6858403

249.  Tomljenovic L. Aluminum and Alzheimer’s disease: after a century of controversy, is there a plausible link? Journal of Alzheimer’s Disease. 2011. 23(4):567–98. PMID:21157018. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/21157018

250.  Hawkes N. Alzheimer’s linked to aluminium pollution in tap water. The Times. April 20, 2006. http://www.thetimes.co.uk/tto/health/article1884130.ece

251.  Sappino AP, Buser R, Lesne L, et al. Aluminium chloride promotes anchorage-independent growth in human mammary epithelial cells. Journal of Applied Toxicology. 2012. 32(3):233–43. PMID: 22223356. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/22223356

252.  U.S. Food and Drug Administration. Study reports aluminum in vaccines poses extremely low risk to infants. Vaccines, Blood & Biologics. Updated January 2012. http://www.fda.gov/BiologicsBloodVaccines/ScienceResearch/ucm284520.htm

253.  Mitkus RJ, King DB, Hess MA, et al. Updated aluminum pharmacokinetics following infant exposures through diet and vaccination. Vaccine. 2011. 29(51):9538–43. PMID:22001122. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/22001122

254.  Vaccine. Elsevier. Accessed February 23, 2016. http://www.journals.elsevier.com/vaccine

255.  Mayo Clinic. A physician’s guide for anti-vaccine parents. 2012. http://newsnetwork.mayoclinic.org/discussion/a-physicians-guide-for-anti-vaccine-parents/

256.  Tomljenovic L & Shaw CA. Aluminum vaccine adjuvants: are they safe? Current Medicinal Chemistry. 2011. 18(17):2630–7. PMID:21568886. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/21568886

257.  Tomljenovic L & Shaw CA. Do aluminum vaccine adjuvants contribute to the rising prevalence of autism? Journal of Inorganic Biochemistry. 2011. 105(11):1489–99. PMID:22099159. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/22099159

258.  Concerns About the Human Papillomavirus Vacine. American College of Pediatricians. January 2016. http://www.acpeds.org/the-college-speaks/position-statements/health-issues/new-concerns-about-the-human-papillomavirus-vaccine

259.  Agency for Toxic Substances and Disease Registry. Public health statement for aluminum. CAS#: 7429-90-5. 2008. U.S. Centers for Disease Control and Prevention. http://www.atsdr.cdc.gov/phs/phs.asp?id=1076&tid=34

260.  Spencer H & Lender M. Adverse effects of aluminum-containing antacids on mineral metabolism. Gastroenterology. 1979. 76(3):603–6. PMID:428714. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/428714

261.  Herzog P & Holtermüller KH. Antacid therapy—changes in mineral metabolism. Scandinavian Journal of Gastroenterology. 1982. 75:56–62. PMID:6293043. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/6293043

262.  Thompson J. Aluminum chelation. The Health Sciences Institute. HSI Online. June 25, 2013. http://hsionline.com/2003/06/25/aluminum-chelation

263.  Wang L, Min M, Li Y, et al. Cultivation of green algae Chlorella sp. in different wastewaters from municipal wastewater treatment plant. Applied Biochemistry and Biotechnology. 2010. 162(4):1174–86. PMID:19937154. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/19937154

Heavy Metals: Copper

264.  Purest Colloids. A brief history of the health support uses of copper. Accessed February 23, 2016. http://www.purestcolloids.com/history-copper.php

265.  Wilson L. Copper toxicity syndrome. The Center for Development. Revised 2015. Drwilson.com. http://www.drlwilson.com/articles/copper_toxicity_syndrome.htm

266.  Singha I, Sagarea AP, Comaa M, et al. Low levels of copper disrupt brain amyloid-β homeostasis by altering its production and clearance. Proceedings of the National Academy of Sciences. 2013. 110(36):14505–14506. doi:10.1073/iti3613110. http://www.pnas.org/content/early/2013/08/14/1302212110

267.  Lovella MA, Robertson JD, Teesdale WJ, et al. Copper, iron and zinc in Alzheimer’s disease senile plaques. Journal of the Neurological Sciences. 1998. 158(1):47–52. PMID:9667777. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/9667777

268.  Russo AJ. Decreased zinc and increased copper in individuals with anxiety. Nutrition and Metabolic Insights. 2011. 4:1–5. PMCID: PMC3738454. PubMed. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3738454

269.  Russo AJ. Analysis of plasma zinc and copper concentration, and perceived symptoms, in individuals with depression, post zinc and anti-oxidant therapy. Nutrition and Metabolic Insights. 2011. 4:19–27. doi:10.4137/NMI.S6760. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/23946658

270.  Russo AJ, Bazin AP, Bigega R, et al. Plasma copper and zinc concentration in individuals with autism correlate with selected symptom severity. Nutrition and metabolic insights. 2012. 5:41–7. PMID:23882147. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/23882147

271.  Kovrižnych JA, Sotníková R, Zeljenková D, et al. Acute toxicity of 31 different nanoparticles to zebrafish (Danio rerio) tested in adulthood and in early life stages—comparative study. Interdisciplinary Toxicology. 2013. 6(2):67–73. PMID: 24179431. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/24179431

272.  Shahabadi N, Khodaei MM, Kashanian S, et al. Interaction of a copper(II) complex containing an artificial sweetener (aspartame) with calf thymus DNA. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2013. 120C:1–6. PMID:24177861. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/24177861

273.  Schilsky ML. Wilson disease: genetic basis of copper toxicity and natural history. Seminars in Liver Disease. 1996. 16(1):83–95. PMID:8723326. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/8723326

274.  Gupte A & Mumper RJ. Copper chelation by D-penicillamine generates reactive oxygen species that are cytotoxic to human leukemia and breast cancer cells. Free Radical Biology & Medicine. 2007. 43(9):1271–8. PMID:17893040. Science.NaturalNews. http://science.naturalnews.com/pubmed/17893040.html

275.  Dietary Reference Intakes (DRIs): Elements. Food and Nutrition Board, Institute of Medicine, National Academies. http://iom.nationalacademies.org/~/media/Files/Activity%20Files/Nutrition/DRIs/New%20Material/6_%20Elements%20Summary.pdf

Heavy Metals: Tin

276.  Eisler R. Tin hazards to fish, wildlife, and invertebrates: a synoptic review. Biological report. U.S. Department of the Interior Fish and Wildlife Service. 1989. 8(1.15). DTIC Online. http://oai.dtic.mil/oai/oai?verb=getRecord&metadataPrefix=html&identifier=ADA322822

277.  Krigman MR & Silverman AP. General toxicology of tin and its organic compounds. Neurotoxicology. 1984. 5(2):129–39. PMID:6390260. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/6390260

278.  Eisler R. Tin hazards to fish, wildlife, and invertebrates: a synoptic review. Biological report. U.S. Department of the Interior Fish and Wildlife Service. 1989. 8(1.15). DTIC Online. http://oai.dtic.mil/oai/oai?verb=getRecord&metadataPrefix=html&identifier=ADA322822

279.  Reicks M & Rader JI. Effects of dietary tin and copper on rat hepatocellular antioxidant protection. Proceedings of the Society for Experimental Biology and Medicine. 1990. 195(1):123–8. PMID:2399253. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/2399253

280.  Shargel L & Masnyj J. Effect of stannous fluoride and sodium fluoride on hepatic mixed-function oxidase activities in the rat. Toxicology and Applied Pharmacology. 1981. 59:452–456. PMID:7268769. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/7268769

281.  Burba JV. Inhibition of hepatic azo-reductase and aromatic hydroxylase by radiopharmaceuticals containing tin. Toxicology Letters. 1983. 18(3):269–72. PMID:6665800. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/6665800

282.  Dwivedi RS, Kaur G, Srivastava RC, et al. Lipid peroxidation in tin intoxicated partially hepatectomized rats. Bulletin of Environmental Contamination and Toxicology. 1984. 33(1):200–209. Springer Link. http://link.springer.com/article/10.1007%2FBF01625531

283.  Food Safety Authority of Ireland. Mercury, lead, cadmium, tin and arsenic in food. Toxicology factsheet series. 2009. 1:1–13. www.fsai.ie/workarea/downloadasset.aspx?id=8412

284.  Wong PTS, Chau YK, Kramar O, et al. Structure–toxicity relationship of tin compounds on algae. Canadian Journal of Fisheries and Aquatic Sciences. 1982. 39(3):483–488. doi:10.1139/f82-066. NRC Research Press. http://www.nrcresearchpress.com/doi/citedby/10.1139/f82-066#.Und0YySLrk0

285.  Dehghan G. & Khoshkam Z. Chelation of toxic tin(II) by quercetin: a spectroscopic study. 2011 International Conference on Life Science and Technology. IPCBEE vol.3. 2011. IACSIT Press, Singapore. http://www.ipcbee.com/vol3/1-B050.pdf

286.  Howe PD. Concise international chemical assessment document 65: tin and inorganic tin compounds. World Health Organization. 2005. ISBN: 9-24153-065-0. www.who.int/ipcs/publications/cicad/cicad_65_web_version.pdf

287.  Nufarm agricultural products. Agri Tin®, EPA Reg No. 55146-72 specimen label, (RV092711). Nufarm Agricultural Products. Crop Data Management Systems, Inc. Accessed February 23, 2016. http://www.cdms.net/ldat/ld3MS005.pdf

288.  Eisler R. Tin hazards to fish, wildlife, and invertebrates: a synoptic review. Biological report. U.S. Department of the Interior Fish and Wildlife Service. 1989. 8(1.15). DTIC Online. http://oai.dtic.mil/oai/oai?verb=getRecord&metadataPrefix=html&identifier=ADA322822

289.  Agency for Toxic Substances and Disease Registry. Tin and tin compounds. Division of toxicology ToxFAQs™. U.S. Centers for Disease Control and Prevention. 2005. U.S. Centers for Disease Control and Prevention. http://www.atsdr.cdc.gov/toxfaqs/tfacts55.pdf

290.  Morry DW, Steinmaus C, et al. Evidence on the carcinogenicity of fluoride and its salts. California Environmental Protection Agency. 2011. http://www.fluoridealert.org/wp-content/uploads/ca-oehha.2011.pdf

291.  McFadden RD. $750,000 given in child’s death in fluoride case. The New York Times. January 20, 1979. Fluoride Alert. http://fluoridealert.org/articles/kennerly

292.  Dehghan G & Khoshkam Z. Chelation of toxic tin(II) by quercetin: a spectroscopic study. 2011 International Conference on Life Science and Technology. IPCBEE vol.3. 2011. IACSIT Press, Singapore. http://www.ipcbee.com/vol3/1-B050.pdf

Chemical Contaminants: Bisphenol A

293.  Bisphenol A Global Industry Group. Bisphenol A: information sheet. Discovery and use. October 2002. http://www.bisphenol-A.org/pdf/DiscoveryandUseOctober2002.pdf

294.  Environment and Human Health, Inc. Bisphenol A introduction: plastics that may be harmful to children and reproductive health. 2008. http://www.ehhi.org/reports/plastics/bpa_intro.shtml

295.  Grignard E, Lapenna S, & Bremer S. Weak estrogenic transcriptional activities of Bisphenol A and Bisphenol S. Toxicology in Vitro. 2012. 26(5):727–31. PMID:22507746. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/22507746

296.  Zsarnovszky A, Le HH, Wang H, et al. Ontogeny of rapid estrogen-mediated extracellular signal-regulated kinase signaling in the rat cerebellar cortex: potent nongenomic agonist and Endocrine disrupting activity of the xenoestrogen Bisphenol A. Neuroendocrinology. 2005. 146(12):5388. http://endo.endojournals.org/content/146/12/5388.short

297.  Breast Cancer Fund. Disrupted development: the dangers of prenatal BPA exposure. 2013. http://www.breastcancerfund.org/assets/pdfs/publications/disrupted-development-the-dangers-of-prenatal-bpa-exposure.pdf

298.  Stahlhut RW, Welshons WV, & Swan SH. Bisphenol A data in NHANES suggest longer than expected half-life, substantial nonfood exposure, or both. Environmental Health Perspectives. 2009. 117(5):784– 789. PMCID:2685842. PubMed. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685842

299.  Breast Cancer Fund. Disrupted development: the dangers of prenatal BPA exposure. 2013. http://www.breastcancerfund.org/assets/pdfs/publications/disrupted-development-the-dangers-of-prenatal-bpa-exposure.pdf

300.  Josephson J. Chemical exposures: Prostate cancer and early BPA exposure. Environmental Health Perspectives. 2006. 114(9):A520. PMCID: PMC1570083. PubMed. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1570083

301.  Konkel L. BPA as a mammary carcinogen: early findings reported in rats. Environmental Health Perspectives. 2013. 121:A284. http://dx.doi.org/10.1289/ehp.121-A284

302.  Lathi RB, Liebert CA, Brookfeild K, et al. Maternal serum biphenol-A (BPA) level is positively associated with miscarriage risk. Fertility and Sterility. 2013. 100(3):S19. http://dx.doi.org/10.1016/j.fertnstert.2013.07.183

303.  Associated Press. Study ties chemical BPA to possible miscarriage risk. October 14, 2013. Fox News. http://www.foxnews.com/health/2013/10/14/study-ties-chemical-bpa-to-possible-miscarriage-risk/

304.  Liao C & Kannan K. High levels of bisphenol A in paper currencies from several countries, and implications for dermal exposure. Environmental science & technology. 2011. 45(16):6761–8. PMID:21744851. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/21744851

305.  U.S. Food and Drug Administration. Bisphenol A (BPA): use in food contact application. Updated March 2013. http://www.fda.gov/newsevents/publichealthfocus/ucm064437.htm

306.  U.S. Department of Health and Human Services. NTP-CERHR monograph on the potential human reproductive and developmental effects of bisphenol A. National Toxicology Program. Center for the Evaluation of Risks to Human Reproduction. September 2008. NIH publication no. 08-5994. http://ntp.niehs.nih.gov/ntp/ohat/bisphenol/bisphenol.pdf

307.  Kumanyika SK & Grier S. Targeting interventions for ethnic minority and low-income populations. The future of children. 2006. 16(1):187–207. doi:10.1353/foc.2006.0005. Project MUSE. http://muse.jhu.edu/journals/foc/summary/v016/16.1kumanyika.html

308.  Treviño RP, Marshall RM, Hale DE, et al. Diabetes risk factors in low-income Mexican-American children. American Diabetes Association. Diabetes Care. 1999. 22(2):202–207. doi:10.2337/diacare.22.2.202. http://care.diabetesjournals.org/content/22/2/202.short

309.  Kirk JK, D’Agostino RBD, Bell RA, et al. Disparities in HbA1c levels between African-American and non-Hispanic white adults with diabetes. American Diabetes Association. Diabetes Care. 2006. 29(9):2130–2136. doi:10.2337/dc05-1973.

310.  Flegal KM, Ezzati TM, Harris M, et al. Prevalence of diabetes in Mexican Americans, Cubans, and Puerto Ricans from the Hispanic Health and Nutrition Examination Survey, 1982–1984. American Diabetes Association. Diabetes Care. 1991. 14(7):628–638. doi:10.2337/diacare.14.7.628. http://care.diabetesjournals.org/content/14/7/628.short

311.  Robbins JM, Vaccarino V, Zhang H, et al. Socioeconomic status and type 2 diabetes in African American and non-Hispanic white women and men: evidence from the Third National Health and Nutrition Examination Survey. American Journal of Public Health. 2001. 91(1):76–83. PMCID:1146485. PubMed. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1446485

312.  Kington RS & Smith JP. Socioeconomic status and racial and ethnic differences in functional status associated with chronic diseases. American journal of Public Health. 1997. 87(5):805–810. PMCID:1381054. PubMed. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1381054

313.  Karter AJ, Mayer-Davis EJ, Selby JV, et al. Insulin sensitivity and abdominal obesity in African-American, Hispanic, and non-Hispanic white men and women: the insulin resistance and atherosclerosis study. American Diabetes Association. Diabetes Care. 1996. 45(11):1547–1555. doi:10.2337/diab.45.11.1547. http://diabetes.diabetesjournals.org/content/45/11/1547.short

314.  Drewnowski A & Darmon N. Food choices and diet costs: an economic analysis. The Journal of Nutrition. 2005. 135(4):900–904. http://jn.nutrition.org/content/135/4/900.short

315.  Horowitz CR, Colson KA, Hebert PL, et al. Barriers to buying healthy foods for people with diabetes: Evidence of environmental disparities. American Journal of Public Health. 2004. 94(9):1549–1554. doi:10.2105/AJPH.94.9.1549. http://ajph.aphapublications.org/doi/abs/10.2105/AJPH.94.9.1549

316.  Drewnowski A & Specter SE. Poverty and obesity: the role of energy density and energy costs. American Journal of Clinical Nutrition. 2004. 79(1):6–16. http://ajcn.nutrition.org/content/79/1/6.short

317.  Morland K, Diez Roux AV, & Wing S. Supermarkets, other food stores, and obesity: the atherosclerosis risk in communities study. American Journal of Preventive Medicine. 2006. 30(4):333– 339. Science Direct. http://www.sciencedirect.com/science/article/pii/S0749379705004836

318.  Candib LM. Obesity and diabetes in vulnerable populations: reflection on proximal and distal Causes. Annals of family medicine. 2007. 5(6):547–556. doi:10.1370/afm.754. http://www.annfammed.org/content/5/6/547.full

319.  Drewnowski A & Darmon N. The economics of obesity: dietary energy density and energy cost. American Journal of Clinical Nutrition. 2005. 82(1):265S–273S. http://ajcn.nutrition.org/content/82/1/265S.short

320.  European Food Safety Authority. Bisphenol A. EFSA. Accessed February 23, 2016. http://www.efsa.europa.eu/en/topics/topic/bisphenol.htm

321.  AFP RelaxNews. France bans contested chemical BPA in food packaging. December 13, 2012. NY Daily News. http://www.nydailynews.com/life-style/health/france-bans-contested-chemical-bpa-food-packaging-article-1.1219611

322.  International Chemical Secretariat. Sweden to initiate a total phase out of bisphenol A. February 1, 2013. http://hkmb.hktdc.com/en/1X09SEGE/hktdc-research/Swedish-environment-minister-calls-for-a-total-phase-out-of-BPA-while-a-damning-report-is-published-on-this-chemical

323.  Austen I. Canada declares BPA, a chemical in plastics, to be toxic. The New York Times. October 13, 2010. http://www.nytimes.com/2010/10/14/world/americas/14bpa.html

324.  Liao C, Liu F, & Kannan K. Bisphenol S, a new bisphenol analogue, in paper products and currency bills and its association with bisphenol A residues. Environmental Science & Technology. 2012. 46(12):6515–6522. PMID:22591511. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/22591511

325.  Cooper JE, Kendig EL, & Belcher SM. Assessment of bisphenol A released from reusable plastic, aluminium and stainless steel water bottles. Chemosphere. 2011. 85(6):943–947. Science Direct. http://www.sciencedirect.com/science/article/pii/S004565351100717X

326.  Yang CZ, Yaniger SI, Jordan VC, et al. Most plastic products release estrogenic chemicals: a potential health problem that can be solved. Environmental Health Perspectives. 2011. 119(7):989–996. PMID:21367689. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/21367689

327.  Bittner, GD. Materials and food additives free of endocrine disruptive chemicals. Application number: 10/852,026. Publication number: US2004/0214926 A1. 2004. http://www.google.com/patents/US20040214926

328.  Fassa P. Eliminate and reverse BPA toxicity. NaturalNews. October 27, 2011. http://www.naturalnews.com/033993_BPA_protection.html

329.  Ibid.

Chemical Contaminants: Hexane

330.  U.S. National Library of Medicine. Jet fuel. Haz-Map® occupational health database. Updated November 2013. U.S. National Institutes of Health. http://hazmap.nlm.nih.gov/category-details?id=698&table=copytblagents

331.  U.S. Environmental Protection Agency. Hexane. Revised January 2000. Technology Transfer Network—Air Toxics. http://www.epa.gov/ttnatw01/hlthef/hexane.html

332.  The National Safety Council. N-hexane chemical backgrounder. 2002. Wayback Machine. http://web.archive.org/web/20070519002303/http://www.nsc.org/ehc/chemical/N-Hexane.htm

333.  Dunnick JK, Graham D, Yang RS, et al. Thirteen-week toxicity study of n-hexane in B6C3F1 mice after inhalation exposure. Toxicology. 1989. 57(2):163–72. PMID:2749745. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/2749745

334.  Howd RA, Rebert CS, Dickinson J, et al. A comparison of the rates of development of functional hexane neuropathy in weanling and young adult rats. Neurobehavioral Toxicology and Teratology. 1983. 5(1):63–8. PMID:6304548. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/6304548

335.  Cavender FL, Casey HW, Salem H, et al. A 13-week vapor inhalation study of n-hexane in rats with emphasis on neurotoxic effects. Fundamental and Applied Toxicology. 1984. 4(2 Pt 1):191– 201. PMID:6724193. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/6724193

336.  Li H, Liu J, Sun Y, et al. N-hexane inhalation during pregnancy alters DNA promoter methylation in the ovarian granulosa cells of rat offspring. Journal of Applied Toxicology. 2013. 34(8):841–56. PMID:23740543. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/23740543

337.  Agency for Toxic Substances and Disease Registry (ATSDR). Toxicological profile for hexane. Public Health Service, U.S. Department of Health and Human Services. 1999. http://www.atsdr.cdc.gov/toxprofiles/tp113.pdf

338.  U.S. Environmental Protection Agency. Hexane. Revised January 2000. Technology Transfer Network—Air toxics. http://www.epa.gov/ttnatw01/hlthef/hexane.html

339.  U.S. Environmental Protection Agency. n-Hexane; CASRN 110-54-3. December 23, 2005. Integrated Risk Information System. http://www.epa.gov/iris/subst/0486.htm

340.  Beall C, Delzell E, Rodu B, et al. Case-control study of intracranial tumors among employees at a petrochemical research facility. Journal of Environmental and Occupational Medicine. 2001. 43(12):1103–13. PMID:11765681. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/11765681

341.  Agency for Toxic Substances and Disease Registry (ATSDR). Toxicological profile for hexane. Public Health Service, U.S. Department of Health and Human Services. 1999. http://www.atsdr.cdc.gov/toxprofiles/tp113.pdf

342.  The Cornucopia Institute. Behind the bean: the heroes and charlatans of the natural and organic soy foods industry—the social, environmental and health impacts of soy. May 8, 2009. http://www.cornucopia.org/2009/05/soy-report-and-scorecard/#more-1375

343.  U.S. Environmental Protection Agency. Emission factor documentation for AP-42, section 9.11.1, vegetable oil processing final report. 1995. Office of Air Quality Planning and Standards Emission Factor and Inventory Group. Research Triangle Park, NC. EPA Contract No. 68-D2-0159. http://www3.epa.gov/ttnchie1/ap42/ch09/bgdocs/b9s11-1.pdf

344.  U.S. Environmental Protection Agency. Emission factor documentation for AP-42, section 9.11.1, vegetable oil processing final report. 1995. Office of Air Quality Planning and Standards Emission Factor and Inventory Group. Research Triangle Park, NC. EPA Contract No. 68-D2-0159. http://www3.epa.gov/ttnchie1/ap42/ch09/bgdocs/b9s11-1.pdf

345.  The National Safety Council. N-hexane chemical backgrounder. 2002. Wayback Machine. http://web.archive.org/web/20070519002303/http://www.nsc.org/ehc/chemical/N-Hexane.htm

346.  The Cornucopia Institute. Behind the bean: the heroes and charlatans of the natural and organic soy foods industry—the social, environmental and health impacts of soy. May 8, 2009. http://www.cornucopia.org/2009/05/soy-report-and-scorecard/#more-1375

347.  Vallaeys C. DHA/ARA—replacing mother—imitating human breast milk in the laboratory, novel oils in infant formula and organic foods: safe and valuable functional food or risky marketing gimmick? The Cornucopia Institute. January 2008. http://cornucopia.org/DHA/DHA_FullReport.pdf

348.  U.S. Centers for Disease Control and Prevention. n-Hexane. 1988 OSHA PEL project documentation. http://www.cdc.gov/niosh/pel88/110-54.html

349.  The Cornucopia Institute. National Organic Standards Board votes on soy lecithin de-listing. May 21, 2009. http://www.cornucopia.org/2009/05/national-organic-standards-board-votes-on-soy-lecithin-de-listing

Chemical Contaminants: Pesticides

350.  Plumer B. We’ve covered the world in pesticides. Is that a problem? Washington post. August 18, 2013. http://www.washingtonpost.com/blogs/wonkblog/wp/2013/08/18/the-world-uses-billions-of-pounds-of-pesticides-each-year-is-that-a-problem/

351.  ReportLinker.com. World agriculture pesticides market. Freedonia. September 2012. 458. http://www.reportlinker.com/p0963176-summary/World-Agricultural-Pesticides-Market.html

352.  Hargis C. U.S. weighing increase in herbicide levels in food supply. Inter Press Service. July 2, 2013. http://www.ipsnews.net/2013/07/u-s-weighing-increase-in-herbicide-levels-in-food-supply

353.  Pesticide Action Network Europe (PANE). Is the pesticide industry really serious about their slogan? Time to change: accepting the challenge. June 26, 2013. http://www.pan-europe.info/old/Resources/Briefings/PANE%20-%202013%20-%20Is%20the%20Pesticide%20Industry%20really%20serious%20about%20their%20slogan.pdf

354.  Short P & Colborn T. Pesticide use in the U.S. and policy implications: a focus on herbicides. Toxicology and Industrial Health. 1999. 15(1–2):240–75. PMID:10188206. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/10188206

355.  National Institutes of Environmental Health Services. Endocrine disruptors resource page. June 5, 2013. http://www.niehs.nih.gov/health/topics/agents/endocrine

356.  U.S. Environmental Protection Agency. Endocrine disruptor screening program (EDSP). Updated December 5, 2013. https://www.epa.gov/endocrine-disruption

357.  U.S. Environmental Protection Agency. Endocrine disruptor screening program for the 21st century: EDSP21 work plan. Office of Chemical Safety and Pollution Prevention. September 30, 2011. http://www.epa.gov/sites/production/files/2015-07/documents/edsp21_work_plan_summary_overview_final.pdf

358.  U.S. Environmental Protection Agency. Endocrine Disruptor Screening Program (EDSP) Overview Updated 10.1.2015. http://www.epa.gov/endocrine-disruption/endocrine-disruptor-screening-program-edsp-overview

359.  U.S. Environmental Protection Agency. Endocrine Disruptor Screening Program for the 21st Century: (EDSP21 Work Plan) September 30, 2011. http://www.epa.gov/sites/production/files/2015-07/documents/edsp21_work_plan_summary_overview_final.pdf

360.  Franz US Patent #3799758A N-phosphonomethyl-glycine phytotoxicant compositions. Original Assignee Monsanto Co. Filing date: August 9, 1971. Publication date: March 26, 1974. http://www.google.com/patents/US3799758?dq=john+e+franz

361.  Material Safety Data Sheet. Roundup Original Herbicide. UC Davis. November 1997. http://greenhouse.ucdavis.edu/pest/pmsds/Roundup.PDF

362.  American Chemical Society. New Weapons on the Way to Battle Wicked Weeds. September 8, 2013.

363.  Hoffman B. GMO crops mean more herbicide, not less. Forbes. July 2, 2013. http://www.forbes.com/sites/bethhoffman/2013/07/02/gmo-crops-mean-more-herbicide-not-less

364.  Adler J. The growing menace from superweeds. Scientific American. 2011. 304:74-79. Nature. http://www.nature.com/scientificamerican/journal/v304/n5/full/scientificamerican0511-74.html

365.  Behrens M, Mutlu N, Chakraborty S, et al. Dicamba resistance: enlarging and preserving biotechnology-based weed management strategies. Center for Plant Science Innovation, University of Nebraska - Lincoln. May 25, 2007. http://digitalcommons.unl.edu/cgi/viewcontent.cgi?article=1031&context=plantscifacpub

366.  U.S. Environmental Protection Agency. Glyphosate; pesticide tolerances. 40 CFR Part 180. [EPA--HQ--OPP--2012--0132; FRL--9384--3]. Final rule. Federal register. May 1, 2013. 78(84):25396--25401. http://www.gpo.gov/fdsys/pkg/FR-2013-05-01/pdf/2013-10316.pdf

367.  GM Watch. U.S. plans to hike allowed glyphosate levels in food supply. July 2, 2013. http://www.gmwatch.org/index.php/news/archive/2013/14769-u-s-plans-to-hike-allowed-glyphosate-levels-in-food-supply

368.  Ibid.

369.  GM Watch. El Salvador votes to ban glyphostate. September 19, 2013. http://gmwatch.org/index.php/news/archive/2013/15066-el-salvador-votes-to-ban-glyphostate

370.  Flint JL & Barrett M. Effects of glyphosate combinations with 2,4-D or dicamba on field bindweed (Convolvulus arvensis). Weed science. 1989. 37(1):12-18 0043-1745. Food and Agriculture Organization of the United Nations. http://agris.fao.org/agris-search/search/display.do?f=1989/US/US89363.xml;US8908991

371.  Ibid.

372.  Bayer CropScience. Bayer CropScience announces intention to construct a state-of-the-art facility for glufosinate-ammonium herbicide. Press release. May 15, 2013. http://www.swissinnovate.org/content.cfm?nav=4&content=10&command=details&id=20189

373.  Monsanto Company. Roundup Ready PLUS weed management solutions. Product page. 2013. http://www.roundupreadyplus.com/Pages/Home.aspx

374.  Monsanto reveals plans for dicamba, glufosinate tolerant pairing. Cotton 24/7. March 1, 2012. http://www.cotton247.com/article/27603/monsanto-reveals-plans-for-dicamba-glufosinate-tolerant-pairing

375.  National Pesticide Information Center. Active Ingredients for 2,4-D. Updated October 12, 2012. http://npic.orst.edu/ingred/24d.html

376.  Muth N. Gene flow might turn wimps into superweeds. Nature. February 20, 2003. 421(6925):785-6. http://www.nature.com/nature/journal/v421/n6925/full/421785c.html

377.  Henderson AM, Gervais JA, Luukinen B, et al. 2010. Glyphosate technical fact sheet. National Pesticide Information Center, Oregon State University Extension Services. http://npic.orst.edu/factsheets/archive/glyphotech.html#reg

378.  Samsel A & Seneff S. Glyphosate’s suppression of cytochrome P450 enzymes and amino acid biosynthesis by the gut microbiome: pathways to modern diseases. Entropy. 2013. 15:1416-1463. DOI:10.3390/e15041416.

379.  Gillam C. Heavy use of herbicide Roundup linked to health dangers—U.S. Study. Reuters. April 25, 2013. http://www.reuters.com/article/2013/04/25/roundup-health-study-idUSL2N0DC22F20130425

380.  Ibid.

381.  Antoniou M, Habib ME, Howard CV, et al. Roundup and birth defects: is the public being kept in the dark? Earth Open Source. 2011. http://earthopensource.org/wp-content/uploads/RoundupandBirthDefectsv5.pdf

382.  Graves L. Roundup: birth defects caused by world’s top-selling weedkiller, scientists say. The Huffington post. June 24, 2011. http://www.huffingtonpost.com/2011/06/24/roundup-scientists-birth-defects_n_883578.html

383.  Center for Biological Diversity. FDA to Start Testing Monsanto’s Glyphosate in Food. EcoWatch, February 2016. http://ecowatch.com/2016/02/18/fda-test-food-glyphosate

384.  U.S. Environmental Protection Agency. Atrazine Interim Reregistration Eligibility Decision (IRED) Q&A’s —January 2003. Pesticides: Topical & Chemical Fact Sheets. Accessed March 1, 2016.

385.  U.S. Environmental Protection Agency. Triazine cumulative risk assessment and atrazine, simazine, and propazine decisions. June 22, 2006. Pesticides: health and safety. May 9, 2012. itrcweb.org/FileCabinet/GetFile?fileID=6880

386.  Pape-Lindstrom PA & Lydy MJ. Synergistic toxicity of atrazine and organophosphate insecticides contravenes the response addition mixture model. Environmental Toxicology and Chemistry. November 1997. 16(11):2415–2420. doi:10.1002/etc.5620161130. Wiley Online Library. http://onlinelibrary.wiley.com/doi/10.1002/etc.5620161130/abstract

387.  Anderson TD & Yan Zhu K. Synergistic and antagonistic effects of atrazine on the toxicity of organophosphorodithioate and organophosphorothioate insecticides to Chironomus tentans (Diptera: Chironomidae). Pesticide Biochemistry and Physiology. 2004. 80(1):54–64. http://dx.doi.org/10.1016/j.pestbp.2004.06.003

388.  U.S. Environmental Protection Agency. Basic information about atrazine in drinking water. Updated September 17, 2013. https://www.epa.gov/ingredients-used-pesticide-products/atrazine-background-and-updates

389.  World Health Organization. Atrazine in drinking water: background document for development of WHO guidelines for drinking-water quality. 2003. http://www.who.int/water_sanitation_health/dwq/atrazinerev0305.pdf

390.  Berry I. Syngenta settles weedkiller lawsuit. Wall Street Journal. May 25, 2012. http://online.wsj.com/news/articles/SB10001424052702304840904577426172221346482

391.  Howard C. Special report: Syngenta’s campaign to protect atrazine, discredit critics. Environmental Health News. June 17, 2013. http://www.environmentalhealthnews.org/ehs/news/2013/atrazine

392.  Wu M, Quirindongo M, Sass J, et al. Poisoning the well: how the EPA is ignoring atrazine contamination in surface and drinking water in the central United States. August 2009. Natural Resources Defense Council (NDRC). https://www.nrdc.org/health/atrazine/files/atrazine.pdf

393.  Hayes TB, et al. 2002. Atrazine-induced hermaphroditism at 0.1 ppb in American leopard frogs (Rana pipiens): laboratory and field evidence. Environmental Health Perspectives. 111:568–575. PMCID:PMC1241446. PubMed. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1241446

394.  De Noyelles F, Kettle D, & Sinn DE. The responses of plankton communities in experimental ponds to atrazine, the most heavily used pesticide in the United States. Ecology. 1982. 63(5):1285–1293. JSTOR. http://www.jstor.org/stable/1938856

395.  Burken JG & Schnoor JL. Uptake and metabolism of atrazine by poplar trees. Environmental Science & Technology. 1997. 31(5):1399–1406. doi:10.1021/es960629v. American Chemical Society. http://pubs.acs.org/doi/abs/10.1021/es960629v

396.  Lennartz B, Louchart X, Voltz M, et al. Diuron and simazine losses to runoff water in Mediterranean vineyards. Journal of Environmental Quality. November 13, 1996. 26(6):1493–1502. doi:10.2134/jeq1997.00472425002600060007x. Alliance of Crop, Soil, and Environmental Science Societies. https://dl.sciencesocieties.org/publications/jeq/abstracts/26/6/JEQ0260061493

397.  Behki RM & Khan SU. Degradation of atrazine, propazine, and simazine by rhodococcus strain B-30. Journal of Agricultural and Food Chemistry. 1994. 42(5):1237–1241. doi:10.1021/jf00041a036. American Chemical Society. http://pubs.acs.org/doi/abs/10.1021/jf00041a036

398.  Casida JE, Gammon DW, Glickman AH, et al. Mechanisms of selective action of pyrethroid insecticides. Annual Review of Pharmacology and Toxicology. April 1983. 23:413–438. doi:10.1146/annurev.pa.23.040183.002213. http://www.annualreviews.org/doi/abs/10.1146/annurev.pa.23.040183.002213?journalCode=pharmtox

399.  Ritter L, Solomon KR, Forget J, et al. Persistent organic pollutants. United Nations Environment Programme. http://cdrwww.who.int/ipcs/assessment/en/pcs_95_39_2004_05_13.pdf

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408.  Cocco P, Blair A, Congia P, et al. Proportional mortality of dichloro-diphenyl-trichloroethane (DDT) workers: a preliminary report. Archives of Environmental Health: An International Journal. 1997. 2(4). DOI: 10.1080/00039899709602202. http://www.tandfonline.com/doi/abs/10.1080/00039899709602202#.Uq19QfaLrk0

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412.  Dees C, Askari M, Foster JS, et al. DDT mimicks estradiol stimulation of breast cancer cells to enter the cell cycle. Molecular Carcinogenesis. 1997. 18(2):107–14. PMID: 9049186. Science.NaturalNews. http://science.naturalnews.com/1997/8807697_DDT_mimicks_estradiol_stimulation_of_breast_cancer_cells_to_enter.html

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425.  U.S. Environmental Protection Agency. Clothianidin—registration status and related information. Updated July 27, 2012. https://www.epa.gov/sites/production/files/2014-10/documents/publicchemicalbranchpmreport102414_dr_3.pdf

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428.  Pesticide Action Network. Parathion: identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information. PAN Pesticides Database—Chemicals. 2010. http://pesticideinfo.org/Detail_Chemical.jsp?Rec_Id=PC35122#Toxicity

429.  Ibid.

430.  Cornell University. Remaining use of pesticide ethyl parathion canceled. Press release. October 13, 2000. http://archive.is/JVZt

431.  U.S. Environmental Protection Agency. Parathion (CASRN 56-38-2). Integrated Risk Information System. Updated August 22, 1988. https://cfpub.epa.gov/ncea/iris2/chemicalLanding.cfm?substance_nmbr=327

432.  U.S. Environmental Protection Agency. Pesticides: reregistration—chlorpyrifos facts. EPA 738-F-01-006. February 2002. Updated May 9, 2012. http://nepis.epa.gov/Exe/ZyPURL.cgi?Dockey=200005F3.txt

433.  Goodman B. Pesticide exposure in womb linked to lower IQ: studies show kids exposed in pregnancy may also have later problems with attention and memory. WebMD health news. April 21, 2011. http://www.webmd.com/baby/news/20110421/pesticide-exposure-in-womb-linked-to-lower-iq

434.  Bouchard MF, Bellinger DC, Wright RO, et al. Attention-deficit/hyperactivity disorder and urinary metabolites of organophosphate pesticides. Pediatrics. 2010. 125(6):e1270–7. doi:10.1542/peds.2009-3058. http://pediatrics.aappublications.org/content/early/2010/05/17/peds.2009-3058.abstract

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446.  Ibid.

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496.  Taylor MR. The de minimis interpretation of the Delaney Clause: legal and policy rationale. Journal of the American College of Toxicology. 1988. 7(4). Sage Journals. http://ijt.sagepub.com/content/7/4/529.extract

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Food Ingredients as Contaminants: Aspartame

498.  Roberts HJ. Aspartame disease: an ignored epidemic. 2001. ISBN-10: 0671217224. West Palm Beach, FL: Sunshine Sentinel Press.

499.  MedlinePlus. Methanol poisoning. U.S. National Library of Medicine. National Institutes of Health. Updated January 30, 2013. http://www.nlm.nih.gov/medlineplus/ency/article/002680.htm

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501.  U.S. Department of Health and Human Services. Symptoms attributed to aspartame in complaints submitted to the FDA. April 20, 1995. SweetPoison.com. http://www.sweetpoison.com/articles/0706/aspartame_symptoms_submit.html

502.  Pattanaargson S, Chuapradit C, & Srisukphonraruk S. Aspartame degradation in solutions at various pH conditions. Food Chemistry and Toxicology. 2001. 66(6):808–809. Online Wiley Library. http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2621.2001.tb15177.x/abstract

503.  Ibid.

504.  Najjar SS, Valaei N, & Mousavi SM. Effect of storage conditions on chemical compositions of diet soft drinks. Pejouhandeh, Shahid Beshti University of Medical Sciences. 2008. 13(1). http://pajoohande.sbmu.ac.ir/browse.php?a_id=660&sid=1&slc_lang=en

505.  Trocho C, Pardo R, Rafecas I, et al. Formaldehyde derived from dietary aspartame binds to tissue components in vivo. Life Sciences. 1998. 63(5). PMID:9714421. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/9714421

506.  Soffritti M, Belpoggi F, Degli Esposti D, et al. First experimental demonstration of the multipotential carcinogenic effects of aspartame administered in the feed to Sprague-Dawley rats. Environmental Health Perspectives. 2006. 114(3):379–385. PMCID:PMC1392232. PubMed. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1392232

507.  Soffritti M, Belpoggi F, Tibaldi E, et al. Life-span exposure to low doses of aspartame beginning during prenatal life increases cancer effects in rats. Environmental Health Perspectives. 2007. 115(9):1293–7. PMID:17805418. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/17805418

508.  Schernhammer ES, Bertrand KA, Birmann BM, et al. Consumption of artificial sweetener- and sugar-containing soda and risk of lymphoma and leukemia in men and women. American Journal of Clinical Nutrition. 2012. 96(6):1419–28. PMID:17805418. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/23097267

509.  Sansom W. Related studies point to the illusion of the artificial. UT Health Science Center San Antonio. June 27, 2011. http://uthscsa.edu/hscnews/singleformat2.asp?newID=3861

510.  Roberts HJ. Aspartame and brain cancer. Lancet. 1997. 349(9048):362. PMID:9024408. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/9024408

511.  Roberts HJ. Overlooked aspartame-induced hypertension. Southern Medical Journal. 2008. 101(9):969. PMID:18708962. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/18708962

512.  Roberts HJ. Aspartame-induced thrombocytopenia. Southern Medical Journal. 2007. 100(5):543. PMID:17534100. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/17534100

513.  Roberts HJ. Perspective on aspartame-induced pseudotumor cerebri. Southern Medical Journal. 2009. 102(8):873. PMID:19593279. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/19593279

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515.  Roberts HJ. Aspartame as a cause of allergic reactions, including anaphylaxis. Archives of Internal Medicine. 1996. 156(9):1027–8. PMID: 8624169. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/8624169

516.  Roberts HJ. Aspartame disease. Texas Heart Institute journal. 2004. 31(1):105. PMCID:P-MC387446. PubMed. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC387446

517.  Roberts HJ. Neurological, psychiatric, and behavioral reactions to aspartame in 505 aspartame reactors. Ch. 45, pp 373-376. Dietary Phenylalanine and Brain Function. Eds. RJ Wurtman & E Ritter-Walker. 1988. ISBN-10: 1461598230. Cambridge, MA: Birkhäuser Boston.

518.  Gold M. Docket no. 02P-0317. Recall aspartame as a neurotoxic drug: file #7: aspartame history. U.S. Food and Drug Administration. January 12, 2003. http://www.fda.gov/ohrms/dockets/dailys/03/Jan03/012203/02P-0317_emc-000202.txt

519.  Olney JW & Ho O. Brain damage in infant mice following oral intake of glutamate, aspartate or cysteine. Nature. 1970. 227:609–611. PMID: 5464249. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/5464249

520.  Gross A. Letter from Dr. Andrian Gross, former FDA investigator and scientist to senator Howard Metzenbaum regarding pre-approval tests by G.D. Searle. Reprinted in U.S. Senate 1987. October 30, 1987. 430–439. http://www.dorway.com/gross.txt

521.  Gordon G. NutraSweet: questions swirl. UPI investigative report. United Press International. October 13, 1987. 483–510. Retrieved from http://www.mpwhi.com/upi_nutrasweet_questions_swirl.pdf

522.  Ibid.

523.  U.S. Department of Health and Human Services. Docket no. 75P-0355. Aspartame: decision of the Public Board of Inquiry. 1980. Retrieved from http://www.dorway.com/pboi.txt

524.  Nill A. The history of aspartame. LEDA at Harvard Law School. http://dash.harvard.edu/bitstream/handle/1/8846759/Nill,_Ashley_-_The_History_of_Aspartame.html?sequence=6

525.  Stout LP. Let them eat cake? A historical analysis of FDA’s decision to approve aspartame. 1997 third year paper. Harvard Law School. http://nrs.harvard.edu/urn-3:HUL.InstRepos:8846766

526.  Testimony. Proceedings and debate of the 99th Congress, 1st session. Congressional record. May 7, 1985.

527.  Roberts HJ. Aspartame disease: an ignored epidemic. 2001. ISBN-10: 1884243177. West Palm Beach, FL: Sunshine Sentinel Press.

528.  Magnuson BA, Burdock GA, Doull J, et al. Aspartame: a safety evaluation based on current use levels, regulations, and toxicological and epidemiological studies. Critical Reviews in Toxicology. 2007. 37(8):629–727. PMID:17828671. PubMed. http://www.ncbi.nlm.nih.gov/pubmed/17828671

529.  HolisticMed.com. Aspartame and manufacturer-funded scientific reviews. 2007. http://www.holisticmed.com/aspartame/burdock/

530.  Walton RG. Survey of aspartame studies: correlation of outcome and funding sources. Accessed February 24, 2016. http://www.dorway.com/peerrev.html

531.  EFSA. Aspartame. European Food Safety Authority. Updated December 10, 2013. http://www.efsa.europa.eu/en/topics/topic/aspartame.htm

532.  Occupational Safety & Health Administration. Methylene chloride. United States Department of Labor. Reviewed March 27, 2012. https://www.osha.gov/SLTC/methylenechloride/

533.  Cong W, Wang R, Cai H, et al. Long-term artificial sweetener acesulfame potassium treatment alters neurometabolic functions in C57BL/6J mice. PLOS ONE. 2013. doi:10.1371/journal. pone.0070257. http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0070257

534.  Adams M. U.S. dairy industry petitions FDA to approve aspartame as hidden, unlabeled additive in milk, yogurt, eggnog and cream. NaturalNews. February 25, 2013. http://www.naturalnews.com/039244_milk_aspartame_fda_petition.html

535.  Federal Register. Flavored milk; petition to amend the standard of identity for milk and 17 additional dairy products. A proposed rule by the Food and Drug Administration. February 20, 2013. https://www.federalregister.gov/articles/2013/02/20/2013-03835/flavored-milk-petition-to-amend-the-standard-of-identity-for-milk-and-17-additional-dairy-products