As always, there are some prerequisites you should ensure you meet before attempting to run a Gameday exercise. Specifically, your teams should be used to instrumenting code with the necessary metrics and alerts to provide a good degree of observability into your production environment. Your teams should have experience working within a well-understood and practiced incident-response process that includes having regular retrospectives to continuously improve in light of production incidents.
Finally, your organization should be accustomed to talking openly about failure and unexpected production incidents, and be committed to processes that encourage continuous improvement. These prerequisites should suggest that your teams have the necessary organizational support and psychological safety to conduct these kinds of resiliency exercises.