Index
AAALAC
Aberdeen knot
absorbable sutures
absorption, of compounds
acclimatisation
acidosis, in anaesthesia
adjuvants
administration of substances
routes
volumes
Advisory Committee on Dangerous Pathogens
Agnatha
air sacs, poultry
alar vein see brachial vein
alcuronium
alfentanil
allergy to laboratory animals (ALA)
allometric scaling
α2-agonists
alphaxalone
alternatives
amphibia
anaesthesia
definition
depth of
health and safety aspects
inhalation
induction of
maintenance of
injectable
induction of
maintenance of
primates
triad of
wild animals
anaesthetic
choice of
circuits
dose rates
wild animals
emergencies
management
analgesics
dose rates
anaphylaxis
Animal Health Act 1981
Animal Procedures Committee
Animal Welfare Act 2006
Animal Welfare and Ethical Review Body
antibiotics, in surgery
antibody production
monoclonal
polyclonal
anticholinergics
anticoagulants
ANOVA
Anurans
anaesthesia of
handling
techniques
apnoea
Apoda
ARRIVE guidelines
arterial sampling and arterial loops
artery forceps
ascites production, for monoclonal antibody
aseptic technique
for administration of substances
aim
principles of
aspirin
Association for the Assessment and Accreditation of Laboratory Animal Care International (AAALAC)
atipamezole
atracurium
atropine
autoclave
Autoclips
axenic animals
azaperone
badger, anaesthetic doses
Bain coaxial circuit
balanced anaesthesia
barbering, mice
barbiturates see pentobarbitone
Basel Declaration
batch surgery
Batrachochytrium dendrobatidis (Bd)
bedding
behavioural ethogram
Bentham, Jeremy
benzocaine, in fish
benzodiazepines
bioavailability
biosecurity
birds
blood sampling
injection volumes
poultry
wild
blood–brain barrier
blood sampling
arterial
equipment for
volumes
see also individual animals
body condition scoring
body temperature, in anaesthesia
brachial vein
bradycardia
British Union for the Abolition of Vivisection (BUAV)
British Veterinary Association (BVA)
brood patch
Bruce effect
BUAV see British Union for the Abolition of Vivisection
building-management system
bupivacaine
buprenorphine
butorphanol
butterfly needles
butyrophenones
BVA see British Veterinary Association
cage labelling
cage paralysis, in rabbits
caging
Callithrix see marmoset
cannulae
indwelling
potential sequelae
recommended sizes
capillary refill time
carbon dioxide euthanasia
carcass disposal
cardiac failure
cardiac puncture
cardiac tamponade
carprofen
cat, blood sampling
catgut suture
cattle
blood sampling
cautery
Centre for Alternatives to Animal Testing
cervical dislocation
chemical hazards
chemical sterilisation
chicken
administration of substances
blood sampling
injection volumes
useful data
see also poultry
chinning, in rabbits
Chlorocebus spp.
Chondrichthyes
chromodacryorrhoea
circle rebreathing circuit
circulation, monitoring during anaesthesia
CITES see Convention on International Trade in Endangered Species
Classification, Labelling and Packaging Regulation
clippers
clove oil, in fish
codes of practice
Committee for Reform of Animal Experimentation (CRAE)
Committee for the Protection of Animals Used for Scientific Purposes
concussion
consequentialist theory
contingent suffering
continuing professional development (CPD)
Control of Substances Hazardous to Health (COSHH) Regulations
controlled drugs
Convention on International Trade in Endangered Species (CITES)
conventional animals
conventional housing
coprophagy
core competencies for licence holders
core modules for training
cost/benefit analysis see harm/benefit analysis
Coturnix coturnix
Council of Europe Convention ETS
CRAE see Committee for Reform of Animal Experimentation
crop see proventriculus
cruciate suture
Cruelty to Animals Act 1876
cumulative suffering
cyanosis
cyclostomes see Agnatha
cynomolgus monkey see macaque
Cyprinid fish
cystocentesis
Danio rerio see zebrafish
day-to-day care person see named animal care and welfare officer
death
confirmation of
definition of
decapitation
decerebrated animals
deontology
Department for Environment, Food and Rural Affairs (DEFRA)
depolarizing agents, in neuromuscular block
desflurane
diathermy
diazepam
diet
diffusion hypoxia
disease
effects on research
sources of
subclinical
disease prevention and health monitoring
disinfection
dislocation of the neck
dissection, surgical
blunt
instruments for
sharp
dissociative anaesthetic agents see ketamine
distress
distress scoring systems see welfare assessment
distribution, of compounds
dog
blood sampling
injection volumes
oral dosing
useful data
domestic fowl see chicken
dorsal lymph sac, in Amphibia
doxapram
drape, surgical
drugs
absorption
distribution
excretion
legal categories
metabolism
storage and record keeping
dual X-ray absorptiometry (DXA)
dystocia
in ferrets
in guinea pigs
ear vein, sampling from
ECG see electrocardiogram
ectotherms
EDTA
EEG see electroencephalogram
electrical hazards
electrical stunning
electrocardiogram (ECG)
electrocution, in fish
electroencephalogram (EEG)
embryonic stem cell manipulation
EMLA cream
endangered species
endotracheal tubes
endotracheal intubation
end point
error
experimental
humane
enflurane
enterohepatic recycling
environment
environmental enrichment
ethanol
ethical considerations
of killing
ethylene oxide
EU Directive 2010/63
European Centre for the Validation of Alternative Methods (ECVAM)
European legislation see EU Directive 2010/63
European Partnership for Alternative Approaches (EPAA)
euthanasia
carbon dioxide
fetal, larval and embryonic forms
other methods
overdose of anaesthetic
physical methods
primates
ungulates
evacuated blood collection tubes
excretion, of compounds
experimental design
Expert Working Group
face mask, anaesthetic
facial vein, sampling from
faecal samples
Farm Animal Welfare Council (FAWC)
feather pecking, in chickens
Federation of European Laboratory Animal Science Associations (FELASA)
health screening requirements for mice
fentanyl
dosage
fentanyl/fluanisone
ferrets
blood sampling
injection volumes
useful data
filter-topped cages
first-pass effect
fish
caudal venous puncture
fistulae, creation and maintenance of
Five Freedoms
flexible film isolators
fluanisone
fluid
requirement
restriction, in primates
flunixin
food and water consumption see individual species
footpad injections
forceps, tissue holding
Freedom of Information Act
Freund's adjuvant
frog see Anurans
Fund for the Replacement of Animals in Medical Experiments (FRAME)
gallamine
gavage
genetic monitoring
genetically altered animals
genetically modified organisms
Contained Use Regulations
gerbil
blood sampling
injection volumes
oral dosing
seizures in
germ-free animals
gizzard see ventriculus
gloves, sterile surgical
glutaraldehyde
glycopyrrolate
gnotobiotic animals
goat
blood sampling
injection volumes
gown, surgical
guinea pig
blood sampling
injection volumes
oral dosing
GV-SOLAS
haemolysis
haemorrhage
haemostasis
equipment for
Hainsworth constant
halothane
Halstead's principles of surgery
hamster
blood sampling
injection volumes
oral dosing
handling techniques
hare, anaesthetic doses
harm/benefit analysis
wild animals
harmful mutants
Harvey, William
hazards
electrical
chemical
from simians
radiation
from wild animals
healing
factors affecting
sequence of
types of
health and safety
Health and Safety at Work Act 1974
health monitoring
animals
primates
health surveillance, personnel
hedgehog, anaesthetic doses
heparin
history of use of animals
Home Office Inspectors
horizontal mattress suture
horses, blood sampling
hot bead sterilizer
housing
humane end points
humane methods of killing
husbandry
see also individual species
hybridoma cells
hypercapnia
hyperoestrogenism, in ferrets
Hypnorm see fentanyl, fentanyl/fluanisone
Hypnovel see midazolam
hypothermia
in anaesthesia, rodents
hypovolaemia
hypoxia
Hystricognathi
ibuprofen
importation of primates
inbred strain
individually ventilated cages
induction chamber
infection
in occupational health
postoperative, sources of
sources of, general
inflammation
injections
footpad/tail base
intra-articular
intracerebral
intradermal
intramuscular
intraperitoneal
intravenous
needle sizes for
subcutaneous
techniques
volumes
injuries, from animals
instruments
choice of
preparation of
surgical
intermittent positive pressure ventilation
International Air Transport Association (IATA), Live Animals Regulations
intra-articular injection
intracerebral injection
intradermal injections
intramuscular injections
intranasal catheter, for anaesthesia
intraperitoneal injections
intravenous injections
in vitro fertilization, in fish
ionising radiation
regulations 1999
sterilization by
IPSOS Mori
isoflurane
isolators, flexible film
IVTIP
jugular vein, sampling from
justification
ketamine
ketoprofen
knock-in animal
knock-out animal
knots, surgical
Laboratory Animal Science Association (LASA)
Guidelines on Rodent Surgery
laryngeal spasm
licence
personal
project
Section 2C
light
lignocaine
local anaesthesia
local ethical review process
lone working
Macaca fascicularis see macaque
Macaca mulatta see macaque
macaque
blood sampling
breeding
diseases of
housing
supply
training
welfare of
Magill anaesthetic circuit
major urinary proteins, mice
malignant hyperthermia
marmoset
behaviour
blood sampling
breeding
housing
Marshall Hall’s principles
Martin’s Act
medetomidine
meloxicam
dosage
metabolism, of compounds
metabolism cage
metamorphosis, in amphibia
Michel clips
midazolam
dosage
milk samples
milk spot
minimum alveolar concentration (MAC)
Misuse of Drugs Regulations
modules, training
monoclonal antibodies
Monocryl see poliglecaprone
morphine
motivation tests
mouse
blood sampling
injection volumes
oral dosing
mouse grimace scale
MS222 see tricaine methanesulphonate
muscle relaxation
mutagenesis
mutant
see also harmful mutants
myopathy, in fish
NACWO see named animal care and welfare officer
naloxone
named animal care and welfare officer (NACWO)
named veterinary surgeon (NVS)
narcotic analgesics
narcotic antagonists
nasal catheter, for anaesthesia
National Anti-Vivisection Society (NAVS)
National Centre for the Three Rs (NC3Rs)
n-butyl cyanoacrylate
nebulisation
needle holders
needles, suture
neostigmine
neuroleptanalgesia
neuromuscular blocking agents
monitoring anaesthesia under
New World monkeys
see also marmoset
nitrous oxide
NMDA receptor anatagonist
noise
in dog accommodation
in primate accommodation
non-absorbable sutures
non-depolarizing agents, in neuromuscular block
non-steroidal anti-inflammatory drugs (NSAIDs)
dosage
nutrition
NVS see named veterinary surgeon
nylon suture
occupational exposure limits
ocular administration
ocular reflexes, in anaesthesia
OECD see Organization for Economic Co-operation and Development
oesophageal stethoscope
Old World monkeys
see also individual species
Onchorynchus mykiss see rainbow trout
opioids
dosage
oral administration
Organization for Economic Co-operation and Development (OECD)
osmosis, reverse
osmotic minipumps
Osteichthyes
osteoporosis, in rabbits
otter, anaesthetic doses
outbred stocks
over-the-needle cannulae
oxalate/fluoride
oxygen flux equation
pain, assessment of
paintbrushing
pancuronium
Papio spp.
paralytic ileus
passive integrated transponder see PIT tags
PCR see polymerase chain reaction
PDS suture see polydioxanone suture
pedal withdrawal reflex
pentobarbitone
persistent oestrus
personal licence
core competencies of holders
personal protective equipment (PPE)
pethidine
pharmacodynamics
pharmacokinetics
phenolics
phenothiazines
pheromones, in mice
phlebitis
physical methods of sterilisation
pig
administration techniques
blood sampling
salt poisoning
stereotypic behaviour
supply
useful data
PIT tags
pithing
poliglecaprone suture
polyclonal antibodies
polydioxanone suture
polyester suture
polyglactin suture
polyglycolic acid suture
polymerase chain reaction (PCR)
polypropylene suture
porcine malignant hyperthermia
positive reinforcement training
postoperative care
poultry
registration of premises
supply of
preen gland, poultry
preference tests
premedication, objectives of
preparation area
prescription-only medicine (POM)
primates
blood sampling
haplorhine
health monitoring
psychological well-being
quarantine
strepsirhine
supply
training
see also individual species
procedure suite, features of
project licence
assessment of
conditions
severity classification
prolene suture
propofol
protected animal, definition
proventriculus
public perception
pulse oximeter
qualifying purposes
quality of life
quarantine, primates
quaternary ammonium compounds
rabbit
blood sampling
injection volumes
radiation hazards
rainbow trout
Rana spp.
rat
blood sampling
injection volumes
oral dosing
REACH see Registration, Evaluation, Authorisation and Restriction of Chemicals
rebreathing circuits
records, personal licence
recovery area
rectal administration
red leg
Reduction, Refinement and Replacement see three Rs
reflective practice
refinement loop
regional anaesthesia
Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH)
regulated procedure, definition
regurgitation
in amphibian
in fish
relative humidity
Reporting of Injuries Diseases and Dangerous Occurrences (RIDDOR)
respiratory depression
respiratory failure
respiratory function, monitoring in anaesthesia
respiratory protective equipment (RPE)
retinal degeneration, rats
retractors
retrospective review
re-use of animals
reverse osmosis
in water supply
in aquaria
rhesus monkey see macaque
RIDDOR see Reporting of Injuries Diseases and Dangerous Occurrences
ringtail
rodents, classification
Royal Society for the Prevention of Cruelty to Animals (RSPCA)
ruminal tympany (bloat)
ruminants
blood sampling
supply
Russell and Burch
salmonid fish
sampling
arterial
blood
DNA
faeces
milk
urine
saphenous vein, sampling from
scalpel blades
Schedule 1
Schedule 1 register
Schedule 2
scissors, surgical
Sciurognathi
screening programmes
scrubbing up
security
sedatives
seizures, in gerbils
selection of animals
sentinel animals
sequential analgesia
severity classification
sevoflurane
sheep
blood sampling
useful data
silk suture
simple interrupted suture
simple continuous suture
skin
animal, preparation for surgery
incision
instruments for
slaughter methods
socialization, dogs
specific pathogen-free animals
squirrel, anaesthetic doses
stainless steel suture
staples, surgical
starve out, in chickens
statistics of animal use
stereotaxic frame
stereotypic behaviour
in dogs
sterilisation
chemical methods
physical methods
stress
subclinical infection
subcutaneous injections
subcuticular suture
sufentanil
supply of laboratory animals
surgeon’s knot
surgery
aseptic technique
dissection of tissues
haemostasis
incision
instruments for
preparation for
techniques
suture
materials
needles
packaging
patterns
sizes
suxamethonium
swim-up stage, in fish
swine see pig
T-piece circuit
tail-base injection
techniques
telemetry
teleost
temperature
body, in anaesthesia
environmental
tetraploidy, in amphibia
three Rs
thrombosis
tissue adhesives
tissue glue
to and fro circuit
towel clips
tourniquet, quick release
training
accredited schemes
licence holders
positive reinforcement
tranquillizers and sedatives
transgenesis
transport of animals
triad of anaesthesia
tricaine methanesulphonate (MS222)
ultrasound
rodents
ungulates
Universities Federation for Animal Welfare (UFAW)
urine
output
sampling
Urodeles
utilitarianism
Vacutainers see evacuated blood collection tubes
variation, minimizing
vascular cannulation
vasodilating agents
vaso-vagal reflex
vecuronium
venipuncture
adverse effects
techniques
ventilated cabinets and cages
ventriculus
Veterinary Medicines Regulations
Veterinary Surgeons Act
Vicryl, Vicryl rapide see polyglactin suture
vitamin D, for New World Monkeys
vole, anaesthesia
vomeronasal organ, mice
waste disposal
water supply
welfare assessment
welfare assessment matrix
Welfare of Animals in Transit Order (WATO)
Whitten effect
wild animals
Wildlife and Countryside Act
wound clips
wound healing
wound infections
risk factors
sources
Xenopus (laevis and tropicalis)
xylazine
zebrafish
zinc toxicity, in ferrets
zoonoses
from primates