In the autobiographical book Bore Hole, Joey Mellen describes his attempts at self-trepanation. Attempts numbers one and two are unsuccessful, resulting in hospital visits and psychiatric evaluations, but no hole. He writes the following of his third attempt: “After some time there was an ominous sounding schlurp and the sound of bubbling. I drew the trepan out and the gurgling continued. It sounded like air bubbles running under the skull as they were pressed out. I looked at the trepan and there was a bit of bone in it. At last!”
Later, Mellen filmed the self-trepanation of his girlfriend, Amanda Feilding, for a film they called Heartbeat in the Brain.
Note: While it certainly sounds fun, most doctors recommend against self-trepanation.