Table 11.1 T1 and T2 relaxation times and fatigue and weakness scores of control and diseased muscles

Subject (images) Vastus lateralis T1 (ms) T2 (ms) Fatigue Weakness
Control (A, B) Normal 1,396 29 0 0
DM (C, D) Inflammation 1,806 49 5.8 3.9
PM (E, F) Fat infitration 569 44 8.5 7.6
Chronic PM (H, I) Fat replacement 370 46 6.6 7.1

Note

High T1 and T2 relaxation times are indicative of inflammation (DM). Fat infitration and replacement are shown by low T1 and high T2 relaxation times. Fatigue and weakness were quantified on a visual analog scale, with 0 meaning no fatigue or weakness and 10 meaning severe fatigue or weakness.