13.1 Introduction
Seborrheic dermatitis is an irritant dermatitis which affects approximately 3% of the population. The sebaceous gland secretions are altered by Malassezia (previously Pityrosporum) species (part of the normal flora) and an irritant dermatitis develops.
13.2 Epidemiology
This chapter focuses on the adolescent and adult populations (not the infantile type). The dermatitis tends to be more widespread in the setting of immunosuppression and underlying neurologic diseases.
13.3 Clinical Findings

(a) Seborrheic dermatitis in an adolescent with erythema and scale. (b) Seborrheic dermatitis shows significant improvement with ketoconazole cream for 2 weeks

Whitish scale of the retroauricular area and scalp from seborrheic dermatitis
13.4 Laboratory
The diagnosis is most often made based on the clinical findings.
13.5 Treatment
Topical antifungal creams such as ketoconazole and shampoos have been noted to be effective in seborrheic dermatitis (see Fig 13.1b). Topical corticosteroids or topical calcineurin inhibitors can be a useful adjunct when inflammation is moderate to severe. Although selenium sulfide and zinc pyrithione shampoos have been prescribed for many years, limited evidence exists for their efficacy.
13.6 Prognosis
Seborrheic dermatitis is fairly persistent, but flares can be prevented with continued use of medications.