7.1 Introduction
Lice infestation in children and adolescents is mainly caused by the head louse (Pediculus humanus capitis). The pubic or crab louse (Phthirus pubis) is transmitted by sexual contact or by co-sleeping. Infestation with the clothing louse (P. humanus humanus) occurs in homeless populations.
7.2 Epidemiology
Head louse infestation (pediculosis capitis) is common in school-aged populations worldwide. All socioeconomic groups are affected. It is spread primarily by head-to-head transmission, and possibly also from fomites. There is an apparent increased prevalence in girls. Head lice may be associated with infection of the scalp by Staphylococcus aureus and/or Group A streptococcus.
7.3 Clinical Findings

Head lice – with nits on hairs and excoriations of the scalp

Crab louse attached to a hair
7.4 Laboratory
Lice found in the hair or after combing may be identified by simple magnification, or by light microscopy. Nits can be distinguished from hair casts or “pseudonits” by dermoscopy or light microscopy.
7.5 Treatment
Over-the-counter treatments for head lice include pyrethrin shampoos, 1% permethrin lotion, isopropyl myristate/cyclomethicone, and dimethicone lotion. Topical medications available by prescription are ivermectin 0.5%, benzyl alcohol 5%, spinosad 0.9%, and malathion 0.5%. Nit combing every 2–3 days after treatment is often recommended to prevent or identify reinfestation.
Pubic or crab lice are treated with 1% permethrin or 0.5% ivermectin lotion. Petrolatum may be applied to the eyelashes, if involved.
7.6 Prognosis
Reinfestation may occur due to medication-resistant lice or further exposure.