TABLE B.14
Clinical Response to BBI Concentrate with Respect to Dose Administered
| Dose1 | Prog2 | NR3 | PR4 | CR5 | N | Response |
|---|---|---|---|---|---|---|
| 200 | 0 | 7 | 1 | 0 | 8 | 12.5 |
| 533 | 0 | 7 | 3 | 1 | 11 | 36.36 |
| 800 | 2 | 5 | 2 | 0 | 9 | 22.22 |
| 1066 | 0 | 1 | 2 | 1 | 4 | 75 |
| Total | 2 | 20 | 8 | 2 | 32 | 31.25 |
1CIU (chymotrypsin inhibitor units).
2Prog (progression), appearance of new lesions, or >50 percent increase in total lesion area.
3NR (no response), <50 percent reduction in total area of all lesions.
4PR (partial response), at least 50 percent reduction in total area of all lesions.
5CR, complete resolution of all lesions at completion of one month of BBI concentrate.
Source: From Armstrong et al., Clin. Cancer. Res., 6:4684–691, 2000b. With permission.