TABLE H.37
Clinical Reports of Selected Herb-Drug Interactions
| Herb and Drug(s) | Results of Interaction |
|---|---|
| Ginkgo (Ginkgo biloba) | |
| Apirin | Serious hyphema |
| Warfarin | Intracerebral hemorrhage |
| Thiazide diuretic | Hypertension |
| Ginseng (Panax spp.) | |
| Warfarin | Decreased INR |
| Phenelzine | Headache and tremor |
| Alcohol | Increased alcohol clearance |
| St. John’s Wort (Hypericum perforatum) | |
| Paroxetine | Lethargy/incoherence |
| Setraline | Mild serotonin syndrome |
| Combined oral contraceptive (ethyloestradiol and desogestrel) | Breakthrough bleeding |
| Valerian (Valeriana officinalis) | |
| Alcohol | A mixture of valepotriates reduces adverse effect of alcohol on concentration |
Source: Adapted from Fugh-Berman, Lancet, 355:134–138, 2001.