TABLE H.38
Anti-inflammatory Effect of (+)-Pinitol on Carrageenan-Induced Paw Edema in Rats1

Treatment Dose (mg/kg, i.p.) Edema Volume (mL) Inhibition (percent)
Control (saline, 3.0 mL/kg, i.p.) 0.90±0.02
Phenylbutazone 100 0.23±0.01* 74.44
(+)-Pinitol 2.5 0.53±0.04* 41.11
5 0.44±0.02* 51.11
10 0.31±0.02* 65.55

1Values are mean±S.E. (n=6).

*p<0.001 versus control; Student’s t-test.

From Singh et al., Fitoterapia, 72:168–170, 2001. With permission.