TABLE L.45
Effect of d-Limonene on Aberrant Crypt/Focus Induced by AOM in Rat Colon1
| ACF/Focus | |||||
|---|---|---|---|---|---|
| Treatment | 1 crypts | 2 crypts | 3 crypts | 4 crypts | 5 crypts |
| AOM alone | 46.0±6.6 | 48.5±11.7 | 28.8±5.4 | 6.6±1.1 | 1.5±1 |
| AOM+d-limonene | 40.5±11.5 | 32.8±6.0b | 14.2±4.1c | 1.5±0.5c | 0.5±0.8 |
1 Significantly different from AOM alone by Student’s t test (b, p<0.05; c, p<0.001). From Kawamori et al., Carcinogenesis, 17:369–372, 1996. With permission.