* The current herbal rage, St. John’s wort, has been gaining some credibility in traditional scientific circles. It inhibits the uptake of serotonin, dopamine, and norepinephrine, and seems to be roughly as effective an antidepressant as Prozac. Moreover, in people who are not taking any additional medication, it appears to have somewhat fewer side effects than do the SSRIs. However, there is increasing evidence that it can seriously disrupt the effectiveness of a wide variety of other medications.