THE RENAISSANCE OF CANNABIS AND MUSHROOMS
Baum, Dan. “Legalize It All.” Harper’s Magazine, March 31, 2016. https://harpers.org/archive/2016/04/legalize-it-all/.
Brand, E. J., & Zhao, Z. (2017). “Cannabis in Chinese Medicine: Are Some Traditional Indications Referenced in Ancient Literature Related to Cannabinoids?” Frontiers in Pharmacology 8, 108. https://doi.org/10.3389/fphar.2017.00108.
Bridgeman, M. B., & Abazia, D. T. (2017). “Medicinal Cannabis: History, Pharmacology, and Implications for the Acute Care Setting.” P&T: A Peer-Reviewed Journal for Formulary Management 42(3), 180–188.
Daniel, J., & Haberman, M. (2018). “Clinical Potential of Psilocybin as a Treatment for Mental Health Conditions.” The Mental Health Clinician 7(1), 24–28. https://doi.org/10.9740/mhc.2017.01.024.
Iffland, K., & Grotenhermen, F. (2017). “An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies.” Cannabis and Cannabinoid Research 2(1), 139–154. https://doi.org/10.1089/can.2016.0034.
King, R. S., & Mauer, M. (2006). “The War on Marijuana: The Transformation of the War on Drugs in the 1990s.” Harm Reduction Journal 3, 6. https://doi.org/10.1186/1477-7517-3-6.
Lee, K. H., Morris-Natschke, S. L., Yang, X., Huang, R., Zhou, T., Wu, S. F., Shi, Q., & Itokawa, H. (2012). “Recent Progress of Research on Medicinal Mushrooms, Foods, and other Herbal Products Used in Traditional Chinese Medicine.” Journal of Traditional and Complementary Medicine 2(2), 84–95.
Lindequist, U., Kim, H. W., Tiralongo, E., & Van Griensven, L. (2014). “Medicinal Mushrooms.” Evidence-Based Complementary and Alternative Medicine: eCAM, 2014, 806180. https://doi.org/10.1155/2014/806180.
McKenna, G. J. (2014). “The Current Status of Medical Marijuana in the United States.” Hawai’i Journal of Medicine & Public Health: A Journal of Asia Pacific Medicine & Public Health 73(4), 105–108.
Mead, A. (2019). “Legal and Regulatory Issues Governing Cannabis and Cannabis-Derived Products in the United States.”Frontiers in Plant Science 10, 697.https://doi.org/10.1186/1477-7517-3-6.
Moore, L. D., & Elkavich, A. (2008). “Who’s Using and Who’s Doing Time: Incarceration, the War on Drugs, and Public Health. American Journal of Public Health 98(9 Suppl), S176—S180. https://doi.org/10.2105/ajph.98.supplement_1.s176.
National Academies of Sciences, Engineering, and Medicine. (2017). The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research. Washington (DC): National Academies Press (US), 15.
O’Shaughnessy, W. B. (1843). “On the Preparations of the Indian Hemp, or Gunjah: Cannabis Indica Their Effects on the Animal System in Health, and their Utility in the Treatment of Tetanus and other Convulsive Diseases.” Provincial Medical Journal and Retrospect of the Medical Sciences 5(123), 363–369.
Stamets, P., & Zwickey, H. (2014). “Medicinal Mushrooms: Ancient Remedies Meet Modern Science.” Integrative Medicine (Encinitas, CA) 13(1), 46–47.
Urits, I., Borchart, M., Hasegawa, M., Kochanski, J., Orhurhu, V., & Viswanath, O. (2019). “An Update of Current Cannabis-Based Pharmaceuticals in Pain Medicine.” Pain and Therapy 8(1), 41–51. https://doi.org/10.1007/s40122-019-0114-4.
LET’S TALK ABOUT CANNABIS
Andre, C. M., Hausman, J. F., & Guerriero, G. (2016). “Cannabis Sativa: The Plant of the Thousand and One Molecules.” Frontiers in Plant Science 7, 19. https://doi.org/10.3389/fpls.2016.00019.
Barcott, Bruce, Chant, Ian, & Downs, David. “Are You Getting the CBD You Paid for? We Put 47 Products to the Test.” Leafly, January 22, 2020. https://www.leafly.com/news/strains-products/cbd-oil-test-results.
Bonn-Miller, M. O., Loflin, M., Thomas, B. F., Marcu, J. P., Hyke, T., & Vandrey, R. (2017). “Labeling Accuracy of Cannabidiol Extracts Sold Online.” JAMA 318(17), 1708–1709. https://doi.org/10.1001/jama.2017.11909.
Bruni, N., Della Pepa, C., Oliaro-Bosso, S., Pessione, E., Gastaldi, D., & Dosio, F. (2018). “Cannabinoid Delivery Systems for Pain and Inflammation Treatment.” Molecules (Basel, Switzerland) 23(10), 2478. https://doi.org/10.3390/molecules23102478.
Centers for Disease Control and Prevention (February 14, 2020). “Outbreak of Lung Injury Associated with the Use of E-Cigarette, or Vaping, Products. Centers for Disease Control and Prevention.” https://www.cdc.gov/tobacco/basic_information/e-cigarettes/severe-lung-disease.html.
Colbin, Annemarie. Food and Healing. New York: Ballantine Books, 1996.
Corroon, J., & Kight, R. (2018). “Regulatory Status of Cannabidiol in the United States: A Perspective.” Cannabis and Cannabinoid Research 3(1), 190–194. https://doi.org/10.1089/can.2018.0030.
D’Souza, D. C., Sewell, R. A., & Ranganathan, M. (2009). “Cannabis and Psychosis/Schizophrenia: Human Studies. European Archives of Psychiatry and Clinical Neuroscience 259(7), 413–431. https://doi.org/10.1007/s00406-009-0024-2.
Fuss, J., Bindila, L., Wiedemann, K., Auer, M. K., Briken, P., & Biedermann, S. V. (2017). “Masturbation to Orgasm Stimulates the Release of the Endocannabinoid 2-Arachidonoylglycerol in Humans.” The Journal of Sexual Medicine 14(11), 1372–1379. doi: 10.1016/j.jsxm.2017.09.016.
Gamble, L. J., Boesch, J. M., Frye, C. W., Schwark, W. S., Mann, S., Wolfe, L., Brown, H., Berthelsen, E. S., & Wakshlag, J. J. (2018). “Pharmacokinetics, Safety, and Clinical Efficacy of Cannabidiol Treatment in Osteoarthritic Dogs.” Frontiers in Veterinary Science 5, 165. https://doi.org/10.3389/fvets.2018.00165.
Gaoni, Y., & Mechoulam, R. (1964). “Isolation, Structure, and Partial Synthesis of an Active Constituent of Hashish.” Journal of the American Chemical Society 86(8), 1646–1647. doi: 10.1021/ja01062a046.
Grant, K. S., Petroff, R., Isoherranen, N., Stella, N., & Burbacher, T. M. (2018). “Cannabis Use During Pregnancy: Pharmacokinetics and Effects on Child Development.” Pharmacology & Therapeutics 182, 133–151. https://doi.org/10.1016/j.pharmthera.2017.08.014.
Huestis, M. A. (2007). “Human Cannabinoid Pharmacokinetics.” Chemistry & Biodiversity 4(8), 1770–1804. https://doi.org/10.1002/cbdv.200790152.
Lemberger, L., Martz, R., Rodda, B., Forney, R., & Rowe, H. (1973). “Comparative Pharmacology of Δ9-Tetrahydrocannabinol and its Metabolite, 11-OH-Δ9-Tetrahydrocannabinol.” Journal of Clinical Investigation 52(10), 2411–2417. doi: 10.1172/jci107431.
Lu, H. C., & Mackie, K. (2016). “An Introduction to the Endogenous Cannabinoid System.” Biological Psychiatry 79(7), 516–525. https://doi.org/10.1016/j.biopsych.2015.07.028.
Maccallum, C. A., & Russo, E. B. (2018). “Practical Considerations in Medical Cannabis Administration and Dosing.” European Journal of Internal Medicine 49, 12–19. doi: 10.1016/j.ejim.2018.01.004.
Mcgrath, S., Bartner, L. R., Rao, S., Packer, R. A., & Gustafson, D. L. (2019). “Randomized Blinded Controlled Clinical Trial to Assess the Effect of Oral Cannabidiol Administration in Addition to Conventional Antiepileptic Treatment on Seizure Frequency in Dogs with Intractable Idiopathic Epilepsy.” Journal of the American Veterinary Medical Association 254(11), 1301–1308. doi: 10.2460/javma.254.11.1301.
Mcguire, P., Robson, P., Cubala, W. J., Vasile, D., Morrison, P. D., Barron, R., Taylor, A., & Wright, S. (2018). “Cannabidiol (CBD) as an Adjunctive Therapy in Schizophrenia: A Multicenter Randomized Controlled Trial.” American Journal of Psychiatry 175(3), 225–231. doi: 10.1176/appi.ajp.2017.17030325.
Mechoulam, R., Fride, E., & Marzo, V. D. (1998). “Endocannabinoids.” European Journal of Pharmacology 359(1), 1–18. doi: 10.1016/s0014-2999(98)00649-9.
Mechoulam, R., & Parker, L. A. (2013). “The Endocannabinoid System and the Brain.” Annual Review of Psychology 64(1), 21–47. doi: 10.1146/annurev-psych-113011-143739.
Moreau, M., Ibeh, U., Decosmo, K., Bih, N., Yasmin-Karim, S., Toyang, N., Lowe, H., & Ngwa, W. (2019). “Flavonoid Derivative of Cannabis Demonstrates Therapeutic Potential in Preclinical Models of Metastatic Pancreatic Cancer.” Frontiers in Oncology 9, 660. https://doi.org/10.3389/fonc.2019.00660.
Muller, C., Morales, P., & Reggio, P. H. (2019). “Cannabinoid Ligands Targeting TRP Channels.” Frontiers in Molecular Neuroscience 11, 487. https://doi.org/10.3389/fnmol.2018.00487.
National Institute on Drug Abuse. (2019, January 29). “Overdose Death Rates.” https://www.drugabuse.gov/related-topics/trends-statistics/overdose-death-rates.
Project CBD. “Cannabis Oil Extraction Methods: How CBD Oil Is Made.” https://www.projectcbd.org/cbd-101/how-is-cbd-oil-made.
Russo, E. B. (2011). “Taming THC: Potential Cannabis Synergy and Phytocannabinoid-Terpenoid Entourage Effects.” British Journal of Pharmacology 163(7), 1344–1364. https://doi.org/10.1111/j.1476-5381.2011.01238.x.
Russo, E. B. (2016). “Clinical Endocannabinoid Deficiency Reconsidered: Current Research Supports the Theory in Migraine, Fibromyalgia, Irritable Bowel, and Other Treatment-Resistant Syndromes.” Cannabis and Cannabinoid Research 1(1), 154–165. doi: 10.1089/can.2016.0009.
Russo, E. B. (2019). “The Case for the Entourage Effect and Conventional Breeding of Clinical Cannabis: No ‘Strain,’ No Gain.” Frontiers in Plant Science 9, 1969. https://doi.org/10.3389/fpls.2018.01969.
Russo, E. B., Burnett, A., Hall, B., & Parker, K. K. (2005). “Agonistic Properties of Cannabidiol at 5-HT1a Receptors.” Neurochemical Research 30(8), 1037–1043. doi: 10.1007/s11064-005-6978-1.
SC Labs. “Explore Cannabinoids.” (2017, April 24). https://www.sclabs.com/cannabinoids/.
SC Labs. “Learn About Terpenes.” (2017, April 24). https://www.sclabs.com/terpenes/.
Sharafi, G., He, H., & Nikfarjam, M. (2019). “Potential Use of Cannabinoids for the Treatment of Pancreatic Cancer.” Journal of Pancreatic Cancer 5(1), 1–7. https://doi.org/10.1089/pancan.2018.0019.
Taha, T., Meiri, D., Talhamy, S., Wollner, M., Peer, A., & Bar-Sela, G. (2019). “Cannabis Impacts Tumor Response Rate to Nivolumab in Patients with Advanced Malignancies.” The Oncologist 24(4), 549–554. doi: 10.1634/theoncologist.2018-0383.
Wang, M., Wang, Y. H., Avula, B., Radwan, M. M., Wanas, A. S., van Antwerp, J., Parcher, J. F., ElSohly, M. A., & Khan, I. A. (2016). “Decarboxylation Study of Acidic Cannabinoids: A Novel Approach Using Ultra-High-Performance Supercritical Fluid Chromatography/Photodiode Array-Mass Spectrometry.” Cannabis and Cannabinoid Research 1(1), 262–271. https://doi.org/10.1089/can.2016.0020.
MEET THE MEDICINAL MUSHROOMS
Akramienė, D., Kondrotas, A., Didžiapetrienė, J., & Kėvelaitis, E. (November 2007). “Effects of ß-Glucans on the Immune System.” Medicina 43(8), 597. https://doi.org/10.3390/medicina43080076.
Baldauf, S. L., & Palmer, J. D. (1993). “Animals and Fungi Are Each Other’s Closest Relatives: Congruent Rvidence from Multiple Proteins.” Proceedings of the National Academy of Sciences of the United States of America 90(24), 11558–11562. https://doi.org/10.1073/pnas.90.24.11558.
Bashir, K., & Choi, J. S. (2017). “Clinical and Physiological Perspectives of β-Glucans: The Past, Present, and Future.” International Journal of Molecular Sciences 18(9), 1906. https://doi.org/10.3390/ijms18091906.
Bastyr University (November 30, 2012). “FDA Approves Bastyr Turkey Tail Trial for Cancer Patients.” https://bastyr.edu/news/general-news/2012/11/fda-approves-bastyr-turkey-tail-trial-cancer-patients.
Chan, G. C., Chan, W. K., & Sze, D. M. (2009). “The Effects of Beta-Glucan on Human Immune and Cancer Cells.” Journal of Hematology & Oncology 2, 25. https://doi.org/10.1186/1756-8722-2-25.
Chang, S.-T., & Wasser, S. P. (2012). “The Role of Culinary-Medicinal Mushrooms on Human Welfare with a Pyramid Model for Human Health.” International Journal of Medicinal Mushrooms 14(2), 95–134. doi: 10.1615/intjmedmushr.v14.i2.10.
Four Sigmatic. “FAQ: Four Sigmatic Mushrooms.” https://us.foursigmatic.com/faq.
Guggenheim, A. G., Wright, K. M., & Zwickey, H. L. (2014). “Immune Modulation from Five Major Mushrooms: Application to Integrative Oncology.” Integrative Medicine (Encinitas, CA), 13(1), 32–44.
Host Defense. “FAQ: Host Defense Mushrooms.” https://hostdefense.com/pages/faqs.
Kubo, K., Aoki, H., & Nanba, H. (1994). “Anti-diabetic Activity Present in the Fruit Body of Grifola frondosa (Maitake). I.” Biological & Pharmaceutical Bulletin 17(8), 1106–1110. doi: 10.1248/bpb.17.1106.
Kulshreshtha, S., Mathur, N., & Bhatnagar, P. (2014). “Mushroom as a Product and Their Role in Mycoremediation.” AMB Express 4, 29. https://doi.org/10.1186/s13568-014-0029-8.
Lai, P-L, et al (2013). “Neurotrophic Properties of the Lion’s Mane Medicinal Mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia.” International Journal of Medicinal Mushrooms 15, 539-554. doi: 10.1615/IntJMedMushr.v15.i6.30.
Lindequist, U., Niedermeyer, T. H., & Jülich, W. D. (2005). “The Pharmacological Potential of Mushrooms.” Evidence-Based Complementary and Alternative Medicine: eCAM 2(3), 285–299. https://doi.org/10.1093/ecam/neh107.
Phan, C.-W., David, P., Naidu, M., Wong, K.-H., & Sabaratnam, V. (2014). “Therapeutic Potential of Culinary-Medicinal Mushrooms for the Management of Neurodegenerative Diseases: Diversity, Metabolite, and Mechanism.” Critical Reviews in Biotechnology 35(3), 355–368. doi: 10.3109/07388551.2014.887649.
Rogers, Robert. The Fungal Pharmacy: the Complete Guide to Medicinal Mushrooms and Lichens of North America. Berkeley, CA: North Atlantic Books, 2011.
Stamets, Paul. Mycelium Running: How Mushrooms Can Help Save the World. Berkeley, CA: Ten Speed Press, 2005.
Terakawa, N., Matsui, Y., Satoi, S., Yanagimoto, H., Takahashi, K., Yamamoto, T., Yamao, J., Takai, S., Kwon, A. H., & Kamiyama, Y. (2008). “Immunological Effect of Active Hexose Correlated Compound (AHCC) in Healthy Volunteers: A Double-Blind, Placebo-Controlled Trial.” Nutrition and Cancer 60(5), 643–651. doi: 10.1080/01635580801993280.
Tuli, H. S., Sandhu, S. S., & Sharma, A. K. (2014). “Pharmacological and Therapeutic Potential of Cordyceps with Special Reference to Cordycepin.” 3 Biotech 4(1), 1–12. https://doi.org/10.1007/s13205-013-0121-9.
Wachtel-Galor, S., Yuen, J., Buswell, J. A., et al. “Ganoderma lucidum (Lingzhi or Reishi): A Medicinal Mushroom,” in Benzie, I. F. F., Wachtel-Galor, S., editors. Herbal Medicine: Biomolecular and Clinical Aspects, second edition. Boca Raton: CRC Press/Taylor & Francis; 2011. Available from: https://www.ncbi.nlm.nih.gov/books/NBK92757/.
Wasser, S.P. (2002). “Medicinal Mushrooms as a Source of Antitumor and Immunomodulating Polysaccharides.” Applied Microbiology and Biotechnology 60(3), 258–274. doi: 10.1007/s00253-002-1076-7.
Wasser, S. P. (2017). “Medicinal Mushrooms in Human Clinical Studies. Part I. Anticancer, Oncoimmunological, and Immunomodulatory Activities: A Review.” International Journal of Medicinal Mushrooms 19(4), 279–317. doi: 10.1615/intjmedmushrooms.v19.i4.10.
Weil, A. (2019, June 10). “Ask Dr. Weil: Is It Safe to Eat Raw Mushrooms?” https://www.prevention.com/health/a20442817/ask-dr-weil-is-it-true-that-you-should-never-eat-mushrooms-raw/
Wolfe, D. (2012). Chaga: King of the Medicinal Mushrooms. Berkeley, CA: North Atlantic Books.
DEEPEN YOUR SLEEP
Babson, K. A., Sottile, J., & Morabito, D. (2017). “Cannabis, Cannabinoids, and Sleep: A Review of the Literature.” Current Psychiatry Reports 19(4). doi: 10.1007/s11920-017-0775-9.
Besedovsky, L., Lange, T., & Born, J. (2012). “Sleep and Immune Function.” Pflugers Archive: European Journal of Physiology 463(1), 121–137. https://doi.org/10.1007/s00424-011-1044-0.
Blessing, E. M., Steenkamp, M. M., Manzanares, J., & Marmar, C. R. (2015). “Cannabidiol as a Potential Treatment for Anxiety Disorders.” Neurotherapeutics: The Journal of the American Society for Experimental NeuroTherapeutics 12(4), 825–836. https://doi.org/10.1007/s13311-015-0387-1.
Cui, X.Y., Cui, S.-Y., Zhang, J., Wang, Z.-J., Yu, B., Sheng, Z.-F., Zhang, X.-Q., Zhang, Y.-H. (2012). “Extract of Ganoderma lucidum Prolongs Sleep Time in Rats.” Journal of Ethnopharmacology 139(3), 796–800. doi: 10.1016/j.jep.2011.12.020.
Liao, L. Y., He, Y. F., Li, L., Meng, H., Dong, Y. M., Yi, F., & Xiao, P. G. (2018). “A Preliminary Review of Studies on Adaptogens: Comparison of Their Bioactivity in TCM with that of Ginseng-like Herbs Used Worldwide. Chinese Medicine 13, 57. https://doi.org/10.1186/s13020-018-0214-9.
Papagianni, E. P., & Stevenson, C. W. (2019). “Cannabinoid Regulation of Fear and Anxiety: An Update.” Current Psychiatry Reports 21(6), 38. https://doi.org/10.1007/s11920-019-1026-z.
Project CBD: Medical Marijuana & Cannabinoid Science (October 29, 2017). “Cannabis & Sleep Disturbances.” https://www.projectcbd.org/medicine/cannabis-sleep-disturbances.
EASE YOUR PAIN
Bouaziz, J., Bar On, A., Seidman, D. S., & Soriano, D. (2017). “The Clinical Significance of Endocannabinoids in Endometriosis Pain Management.” Cannabis and Cannabinoid Research 2(1), 72–80. https://doi.org/10.1089/can.2016.0035.
Center for Drug Evaluation and Research. (n.d.). Ibuprofen Drug Facts Label. https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/ibuprofen-drug-facts-label.
Kaufman, D. W., Kelly, J. P., Battista, D. R., Malone, M. K., Weinstein, R. B., & Shiffman, S. (2018). “Exceeding the Daily Dosing Limit of Nonsteroidal Anti-inflammatory Drugs Among Ibuprofen Uusers. Pharmacoepidemiology and Drug Safety 27(3), 322–331. doi: 10.1002/pds.4391.
Miller, Sara G. (June 6, 2017). “Marijuana for Menstrual Cramps? New York Considers Medical Option.” Live Science. Retrieved from https://www.livescience.com/59370-marijuana-period-cramps-dysmenorrhea.html.
Pazzi, F., Fabero, R. F. (2017) “Effects of Ganoderma lucidum on Pain in Women with Fibromyalgia.” Fibromyalgia Open Access 2, 115.
Sanodiya, B., Thakur, G., Baghel, R., Prasad, G., & Bisen, P. (2009). “Ganoderma lucidum: A Potent Pharmacological Macrofungus.” Current Pharmaceutical Biotechnology 10(8), 717–742. doi: 10.2174/138920109789978757.
Vučković, S., Srebro, D., Vujović, K. S., Vučetić, Č., & Prostran, M. (2018). “Cannabinoids and Pain: New Insights from Old Molecules.” Frontiers in Pharmacology 9, 1259. https://doi.org/10.3389/fphar.2018.01259.
Wiese, B., & Wilson-Poe, A. R. (2018). “Emerging Evidence for Cannabis’ Role in Opioid Use Disorder.” Cannabis and Cannabinoid Research 3(1), 179–189. https://doi.org/10.1089/can.2018.0022.
CALM STRESS AND ANXIETY
Ryu, S., Kim, H. G., Kim, J. Y., Kim, S. Y., & Cho, K.-O. (2018). “Hericium erinaceus Extract Reduces Anxiety and Depressive Behaviors by Promoting Hippocampal Neurogenesis in the Adult Mouse Brain.” Journal of Medicinal Food 21(2), 174–180. doi: 10.1089/jmf.2017.4006.
Zhao, H., Zhang, Q., Zhao, L., Huang, X., Wang, J., & Kang, X. (2012). “Spore Powder of Ganoderma lucidum Improves Cancer-Related Fatigue in Breast Cancer Patients Undergoing Endocrine Therapy: A Pilot Clinical Trial.” Evidence-Based Complementary and Alternative Medicine 2012, 1–8. doi: 10.1155/2012/809614.
INCREASE YOUR ENERGY, ENHANCE YOUR FOCUS, UPLIFT YOUR MOOD
Huang, W. J., Chen, W. W., & Zhang, X. (2016). “Endocannabinoid System: Role in Depression, Reward and Pain Control (Review).” Molecular Medicine Reports 14(4), 2899–2903. https://doi.org/10.3892/mmr.2016.5585.
Le Foll, B., Gorelick, D. A., & Goldberg, S. R. (2009). “The Future of Endocannabinoid-Oriented Clinical Research After CB1 Antagonists. Psychopharmacology 205(1), 171–174. https://doi.org/10.1007/s00213-009-1506-7.
Pandey, R., Mousawy, K., Nagarkatti, M., & Nagarkatti, P. (2009). “Endocannabinoids and Immune Regulation.” Pharmacological Research 60(2), 85–92. https://doi.org/10.1016/j.phrs.2009.03.019
Prenderville, J. A., Kelly, Á. M., & Downer, E. J. (2015). “The Role of Cannabinoids in Adult Neurogenesis.” British Journal of Pharmacology 172(16), 3950–3963. https://doi.org/10.1111/bph.13186.
SUPERCHARGE YOUR SEX DRIVE
Androvicova, R., Horacek, J., Stark, T., Drago, F., & Micale, V. (2017). “Endocannabinoid System in Sexual Motivational Processes: Is It a Novel Therapeutic Horizon?” Pharmacological Research 115, 200–208. doi: 10.1016/j.phrs.2016.11.021.
Lin, B., & Li, S. “Cordyceps as an Herbal Drug,” in Benzie, I. F. F., Wachtel-Galor, S., editors, Herbal Medicine: Biomolecular and Clinical Aspects, second edition. Boca Raton: CRC Press/Taylor & Francis; 2011. Available from: https://www.ncbi.nlm.nih.gov/books/NBK92758/.
Lynn, B. K., López, J. D., Miller, C., Thompson, J., & Campian, E. C. (2019). “The Relationship between Marijuana Use Prior to Sex and Sexual Function in Women.” Sexual Medicine 7(2), 192–197. https://doi.org/10.1016/j.esxm.2019.01.003.
Panda, A. K., & Swain, K. C. (2011). “Traditional Uses and Medicinal Potential of Cordyceps Sinensis of Sikkim.” Journal of Ayurveda and Integrative Medicine 2(1), 9–13. https://doi.org/10.4103/0975-9476.78183.
NOURISH YOUR SKIN
Sheriff, T., Lin, M. J., Dubin, D., & Khorasani, H. (2019). “The Potential Role of Cannabinoids in Dermatology.” Journal of Dermatological Treatment, 1–7. doi: 10.1080/09546634.2019.1675854.
Yun, J. S., Pahk, J. W., Lee, J. S., Shin, W. C., Lee, S. Y., & Hong, E. K. (2011). “Inonotus obliquus Protects Against Oxidative Stress-induced Apoptosis and Premature Senescence.” Molecules and Cells 31(5), 423–429. https://doi.org/10.1007/s10059-011-0256-7.
Wang, J., Cao, B., Zhao, H., & Feng, J. (2017). “Emerging Roles of Ganoderma Lucidum in Anti-Aging.” Aging and Disease 8(6), 691–707. https://doi.org/10.14336/AD.2017.0410.
CANNABIS AND CANCER
Abrams, D. I. (2016). “Integrating Cannabis into Clinical Cancer Care.” Current Oncology (Toronto) 23(2), S8—S14. https://doi.org/10.3747/co.23.3099
Bienenstock, D. (February 6, 2019). “A Patient’s Guide to Using Cannabis for Cancer.” https://www.leafly.com/news/health/how-to-use-medical-marijuana-for-cancer.
Dariš, B., Tancer Verboten, M., Knez, Ž., & Ferk, P. (2019). “Cannabinoids in Cancer Treatment: Therapeutic Potential and Legislation.” Bosnian Journal of Basic Medical Sciences 19(1), 14–23. https://doi.org/10.17305/bjbms.2018.3532.
National Cancer Institute. “Cannabis and Cannabinoids.” https://www.cancer.gov/about-cancer/treatment/cam/hp/cannabis-pdq.
National Institute on Drug Abuse. “Marijuana as Medicine.” https://www.drugabuse.gov/publications/drugfacts/marijuana-medicine.
The Realm of Caring. “Cancer Cannabis Dosing Guidelines.” http://www.theroc.us/images/CancerDosing.pdf.
Sharafi, G., He, H., & Nikfarjam, M. (2019). “Potential Use of Cannabinoids for the Treatment of Pancreatic Cancer.” Journal of Pancreatic Cancer 5(1), 1–7. https://doi.org/10.1089/pancan.2018.0019.
Yasmin-Karim, S., Moreau, M., Mueller, R., Sinha, N., Dabney, R., Herman, A., & Ngwa, W. (2018). “Enhancing the Therapeutic Efficacy of Cancer Treatment With Cannabinoids.” Frontiers in Oncology 8, 114. https://doi.org/10.3389/fonc.2018.00114.
MEDICINAL MUSHROOMS AND CANCER
Aleem, E. (2013). “β -Glucans and their Applications in Cancer Therapy: Focus on Human Studies.” Anti-Cancer Agents in Medicinal Chemistry 13(5), 709–719. doi: 10.2174/1871520611313050005
Blagodatski, A., Yatsunskaya, M., Mikhailova, V., Tiasto, V., Kagansky, A., & Katanaev, V. L. (2018). “Medicinal Mushrooms as an Attractive New Source of Natural Compounds for Future Cancer Therapy.” Oncotarget 9(49), 29259–29274. https://doi.org/10.18632/oncotarget.25660.
Konno, S. (2009). “Synergistic Potentiation of D-fraction with Vitamin C as Possible Alternative Approach for Cancer Therapy.” International Journal of General Medicine 2, 91–108. https://doi.org/10.2147/ijgm.s5498.
Król, S. K., Kiełbus, M., Rivero-Müller, A., & Stepulak, A. (2015). “Comprehensive Review on Betulin as a Potent Anticancer Agent.” BioMed Research International 2015, 584189. https://doi.org/10.1155/2015/584189.
Lee, H. S., Kim, E. J., & Kim, S. H. (2015). “Ethanol Extract of Innotus Obliquus (Chaga mushroom) Induces G1 Cell Cycle Arrest in HT-29 Human Colon Cancer Cells.” Nutrition Research and Practice 9(2), 111–116. https://doi.org/10.4162/nrp.2015.9.2.111.
PDQ Integrative, Alternative, and Complementary Therapies Editorial Board (January 17, 2019). “Medicinal Mushrooms (PDQ®): Patient Version,” in PDQ Cancer Information Summaries. Bethesda (MD): National Cancer Institute. https://www.ncbi.nlm.nih.gov/books/NBK424937/.
Torkelson, C. J., Sweet, E., Martzen, M. R., Sasagawa, M., Wenner, C. A., Gay, J., Putiri, A., & Standish, L. J. (2012). “Phase 1 Clinical Trial of Trametes Versicolor in Women with Breast Cancer.” ISRN Oncology 2012, 251632. https://doi.org/10.5402/2012/251632.
Wasser, S. (2014). “Medicinal Mushroom Science: Current Perspectives, Advances, Evidences, and Challenges.” Biomedical Journal 37(6), 345. doi: 10.4103/2319-4170.138318.
Zhang, M., Zhang, Y., Zhang, L., & Tian, Q. (2019). “Mushroom Polysaccharide Lentinan for Treating Different Types of Cancers: A Review of 12 Years Clinical Studies in China.” Progress in Molecular Biology and Translational Science Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics—Part B, 297–328. doi: 10.1016/bs.pmbts.2019.02.013.
OTHER ADVANCED CASES
Elms, L., Shannon, S., Hughes, S., & Lewis, N. (2019). “Cannabidiol in the Treatment of Post-Traumatic Stress Disorder: A Case Series.” Journal of Alternative and Complementary Medicine 25(4), 392–397. https://doi.org/10.1089/acm.2018.0437.
Mithoefer, M. C., Feduccia, A. A., Jerome, L., Mithoefer, A., Wagner, M., Walsh, Z., Hamilton, S., Yazar-Klosinski, B., Emerson, A., & Doblin, R. (2019). “MDMA-Assisted Psychotherapy for Treatment of PTSD: Study Design and Rationale for Phase 3 Trials Based on Pooled Analysis of Six Phase 2 Randomized Controlled Trials.” Psychopharmacology 236(9), 2735–2745. https://doi.org/10.1007/s00213-019-05249-5.
Neumeister, A., Normandin, M. D., Pietrzak, R. H., Piomelli, D., Zheng, M. Q., Gujarro-Anton, A., Potenza, M. N., Bailey, C. R., Lin, S. F., Najafzadeh, S., Ropchan, J., Henry, S., Corsi-Travali, S., Carson, R. E., & Huang, Y. (2013). “Elevated Brain Cannabinoid CB1 Receptor Availability in Post-traumatic Stress Disorder: A Positron Emission Tomography Study.” Molecular Psychiatry 18(9), 1034–1040. https://doi.org/10.1038/mp.2013.61.
Perucca, E. (2017). “Cannabinoids in the Treatment of Epilepsy: Hard Evidence at Last?” Journal of Epilepsy Research 7(2), 61–76. https://doi.org/10.14581/jer.17012.
MAGIC MUSHROOMS: THE CASE FOR PSILOCYBIN
Carhart-Harris, R. L., Bolstridge, M., Day, C., Rucker, J., Watts, R., Erritzoe, D. E., Kaelen, M., Giribaldi, B., Bloomfield, M., Pilling, S., Rickard, J. A., Forbes, B., Feilding, A., Taylor, D., Curran, H. V., & Nutt, D. J. (2018). “Psilocybin with Psychological Support for Treatment-Resistant Depression: Six-Month Follow-Up.” Psychopharmacology 235(2), 399–408. https://doi.org/10.1007/s00213-017-4771-x.
Carhart-Harris, R. L., & Goodwin, G. M. (2017). “The Therapeutic Potential of Psychedelic Drugs: Past, Present, and Future.” Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology 42(11), 2105–2113. https://doi.org/10.1038/npp.2017.84.
Griffiths, R. R., Johnson, M. W., Carducci, M. A., Umbricht, A., Richards, W. A., Richards, B. D., Cosimano, M. P., & Klinedinst, M. A. (2016). “Psilocybin Produces Substantial and Sustained Decreases in Depression and Anxiety in Patients with Life-threatening Cancer: A Randomized Double-blind Trial.” Journal of Psychopharmacology 30(12), 1181–1197. https://doi.org/10.1177/0269881116675513.
Haze, V., & Mandrake, K. (2016). The Psilocybin Mushroom Bible. Toronto, Canada: Green Candy Press.
Prochazkova, L., Lippelt, D. P., Colzato, L. S., Kuchar, M., Sjoerds, Z., & Hommel, B. (2018). “Exploring the Effect of Microdosing Psychedelics on Creativity in an Open-Label Natural Setting.” Psychopharmacology 235(12), 3401–3413. https://doi.org/10.1007/s00213-018-5049-7.
“The Safety and Efficacy of Psilocybin in Participants With Treatment Resistant Depression—Full Text View.” (n.d.). Retrieved from https://clinicaltrials.gov/ct2/show/NCT03775200.
The Third Wave. “The Ultimate Guide to Psilocybin Mushrooms.” https://thethirdwave.co/psychedelics/shrooms/