The Beta-Site APP-Cleaving Enzyme (BACE) is a therapeutic target for Alzheimer's disease. It produces Alzheimer's disease peptides.
The BACE dataset is a collection of small molecule inhibitors across a three order of magnitude (nM to μM) range of IC50s along with crystallographic structures that were previously unknown.
You can take a look at https://drugdesigndata.org/about/grand-challenge-4/bace for more details.