57 Anesthesiology ethics

Gail A. Van Norman

Mrs. C is an 86-year-old woman with metastatic colon cancer, scheduled for surgery for bowel obstruction. She is hypotensive and tachycardic. She agrees to invasive monitoring but does not want to be resuscitated if her heart stops in the operating room. Her surgeon argues not to place invasive monitors because she is a “no code.”

Mr. D is scheduled to be executed for the rape and murder of a child in the state of Missouri. He appeals his sentence on the grounds that lethal injection subjects the prisoner to potential prolonged suffering during the execution process. A court rules that an anesthesiologist must be present to assure unconsciousness before administration of the paralytic agent and potassium. The ruling states that the anesthesiologist must personally mix the drugs and administer them, or directly supervise their administration.

What is anesthesiology ethics?

Conflicts concerning patient choices and autonomy are particularly challenging in anesthesiology, in part because anesthesia care routinely alters patient consciousness, interferes with patient competence, and restricts or abolishes physical autonomy. Anesthesiologists are at times expected to use their knowledge and skills for the very purpose of abolishing patient resistance. Such expectations present conflicts with core values in the ethical practice of anesthesiology, and of medicine itself. Navigating the complicated course among ethical principles governing patient choice, fulfillment of beneficent intentions, and preservation of professional integrity requires understanding of ethical values and principles such as respect for patient autonomy, beneficence, non-maleficence, preservation of human dignity, promotion of patient safety, and safeguarding of professional integrity. When patients refuse resuscitation in the operating room (OR), anesthesiologists may experience conflicts between the ethical principle of respect for patient autonomy and choice, and professional imperatives to act beneficently. In the matter of executions, anesthesiologists must answer the question of whether they should engage in acts that superficially resemble medical care but require a personal moral transformation embodying the very antithesis of the medical profession’s philosophies of valuing human life, respecting individuals, and taking moral responsibility for their actions.

Why is anesthesiology ethics important?

Ethics
The competent patient with intact autonomy

Requesting a patient’s permission for a medical procedure implies that the patient can and will sometimes deny that permission. Physicians are obliged to honor informed and competent refusals, lest the “consent” process be devoid of actual choice or autonomy. The tension between “informed consent” and “informed refusal” is especially great when one course of action would likely sustain life, and another would likely lead to death.

Physicians often argue that “benefits” outweigh “harms” of cardiopulmonary resuscitation (CPR) in the OR. In-hospital CPR is associated with low overall survival rates of 10–15% (Brindley et al., 2002; Myrianthefs et al., 2003; Abella et al., 2005) and devastating neurological injuries (Zandbergen et al., 2003). In contrast, survival rates for CPR in the operating room approach 90% (Reis et al., 2002). The difference reflects underlying causes of cardiac arrest; in-hospital arrests are often caused by severe underlying disease. When an arrest occurs in an unmonitored situation, resuscitation may be delayed, contributing to poor outcomes. In the OR, underlying causes of cardiac arrest are often identifiable and reversible, and intervention occurs immediately (Olsson and Hallen, 1988; Sprung et al., 2003).

Allowing a patient to die in the OR from a cardiac arrest that is highly treatable does not appear to many OR physicians to uphold the principle of beneficence. But patients may not believe that resuscitation from cardiac arrest is “beneficial” if they are left with significant physical impairments or are merely revived to die in a short time of a preexisting terminal illness. In weighing the beliefs of the patient and their physicians, physicians are ethically obliged to give priority to patients’ perception of benefits and harms over their own (Clemency and Thompson, 1993, 1994; SUPPORT Principle Investigators, 1995; Wenger et al., 1997).

Some anesthesiologists claim that anesthesia is “ongoing resuscitation,” and that the two cannot be separated from one another. This unfortunate statement implies that anesthesia is riskier than it actually is, and that cardiac arrest is more likely to occur in the OR than other hospital settings, when in fact the opposite is true. Although anesthetic care and CPR share some common techniques, they are almost always easily distinguishable from one another. Would any anesthesiologist seriously argue that a patient undergoing mechanical ventilation during an elective laparoscopy is being “resuscitated?” Or that CPR is a routine part of anesthesia care? Although some life-sustaining procedures, such as assisted ventilation, are necessary during some surgeries, CPR is not integral to surgery, is rarely needed in the OR, and only then to treat rare complications which OR physicians strive to avoid.

Many physicians feel that it may be appropriate to allow a patient with a do-not-resuscitate (DNR) order to die from a terminal disease, but that they are ethically obliged to “rescue” a patient whose cardiac arrest is a consequence of the physician’s actions (Casarett and Ross, 1997; Casarett et al., 1999). Examples include arrests caused by drug reactions, hemorrhage, or arrhythmia provoked by surgical manipulation. Often, however, complications are not attributable to only one action or cause, nor are they usually the result of negligent care. Primary therapies and treatments for the complications of primary therapies both have their origins in the problem for which the patient sought medical care, and it is difficult to reason that the patient may refuse one but not the other (Ross, 2003).

Finally, withholding surgery that a patient desires, such as surgery to relieve a bowel obstruction, unless the patient also agrees to submit to unwanted procedures that are not integral to the surgery, such as CPR, is coercive and, therefore, unethical. As Walker (1991) stated: “Surgery may provide palliative treatment for otherwise untreatable disease. Suspension of DNR orders in the perioperative period places the patients in the unfair position of having to weigh the benefits of palliative treatment against the risks of unwanted resuscitation.”

The competent “patient” with compromised autonomy

Founding principles of the medical profession prohibited killing, but those principles must now be reconciled in modern cultures that accept physician participation in pregnancy terminations, physician-assisted suicide, and euthanasia. Arguments favoring physician involvement in executions often cite the principle of respect for “autonomy” by helping a prisoner to have their “desired” mode of death (Baum, 2001; Clark, 2006). Prisoners, however, are among the most vulnerable of society’s constituents. This is reflected in efforts to regulate how the state or medical researchers can treat prisoners. The Nuremburg Code (1949) restricting the use of human subjects in medical experimentation arose out of experiments on prisoners during the second, World War. The United Nations (UN) Third Geneva Convention mandated humane treatment of prisoners of war, and protections against violence, intimidation, public curiosity or insults, torture, or coercion (UN, 1949).

A state of imprisonment is one of severely restricted autonomy. But execution represents the ultimate destruction of autonomy. Prisoners do not usually seek capital punishment of their own free will, and when they do, mental incapacity is cited as a defense against their execution (Blume, 2005). With regard to autonomy and rights, a prisoner’s situation is less like that of an autonomous adult than that of a vulnerable older child, who possesses intellectual capacity, without many legal rights. Arguments seeking to justify physician participation in execution could theoretically cite the ethical value of preserving a prisoner’s dignity, but not respect for non-existent autonomy.

Beneficence-based arguments that physician executioners are needed and best qualified to relieve suffering are based on flawed concepts of “suffering,” as those physical sensations experienced by the prisoner during execution, and a limited concept of beneficence as being measured by only one aspect of the execution process. Capital punishment causes suffering in many persons, including victims’ families, convicts’ families, and prison staff (Osofsky and Osofsky, 2002), none of which is resolvable by medical means. There are also no data to support contentions that competent technicians are less capable of efficient, painless, or “humane” executions than physicians. Forensic examination reveals that all execution methods are fraught with complications, even when physicians are involved. The most frequent problems associated with lethal injection are difficulties obtaining vascular access, and painful subcutaneous infiltration of medications, delaying onset of unconsciousness (Khan and Leventhal, 2002). A recent study suggests that blood levels of hypnotics administered during lethal injections are inadequate to assure unconsciousness in almost half of cases (Koniaris et al., 2005). There is no evidence that these problems would be significantly lessened in the hands of physician–executioners, when complications with intravenous access and awareness during anesthesia also occur during the course of routine medical care.

Arguments invoking the principle of beneficence to justify physician involvement in criminal executions have historically been associated with subsequent “slippery slope” justifications for physician involvement in the killing of persons who have never faced an accuser or had a fair hearing, including those with physically or mentally handicaps or other social “flaws” (Hinman, 1944; Jonsen, 1993; Pelligrino and Thomasma, 2000). If physicians accept a role in executions based on beneficence arguments, it becomes harder to draw the line at participation in other state-sponsored activities, such as torture, coercion, and “medical incarceration,” because they too are often defended as being “beneficial” to society (Silver, 1986; van Es, 1992; Pelligrino, 1993; Pelligrino and Thomasma, 2000).

Physician participation in executions produces many harms and is, therefore, not “non-maleficent.” It causes harm through the “medicalization” of a non-medical and distasteful act in order to defuse moral objections and render it more acceptable to an increasingly skeptical public. In this regard, it parallels historical misuse of psychiatric diagnoses and mental illness-based incarcerations to manage non-medical social or political problems (Rood, 1979; Gluzman, 1991; Adler et al., 1992). Agreeing to participate in executions transforms the physician into a deceptive “double agent,” who is acting on behalf of the state while appearing to act on behalf of the “patient” (Silver, 1986; van Es, 1992; Pelligrino, 1993). It erodes public respect and trust (Sikora and Fleischman, 1999). It also sometimes undoubtedly engages the physician in the killing of innocent persons (Hinman, 1944; Dieter, 2004; Gross et al., 2005).

Physicians have typically tried to divorce the issue of physician participation in executions from the question of whether capital punishment itself is moral. But the morality of engaging in an activity simply cannot be completely separated from moral aspects of the activity itself (Thorburn, 1987; Hastings Center, 1996). The practice of medicine involves consideration of the principle of justice, and the extent to which capital punishment intrinsically fulfills that principle is relevant to whether physician participation in executions is consistent with professional integrity.

DNA technology has proven that innocent people are wrongly convicted of capital crimes and sentenced to die, and that innocent people almost certainly have actually been executed (Langer, 2001; Dieter, 2004; Gross et al., 2005). Capital punishment for comparable crimes is applied unequally across racial and socioeconomic groups (Baldus and Woodworth, 1997). Studies consistently demonstrate that it does not deter violent crime (Sorensen et al., 1999; US Department of Justice, 2003; Rosenfeld, 2004; Berk, 2005). It unfairly consumes economic resources, because it is much more expensive than lifelong incarceration (Cook et al., 1992; Dieter, 1992; Forsberg, 2005). It fuels ethically objectionable proposals to curtail existing “safeguards” – the appeals process – in order to cut costs (US Senate, 2005). It does not appear to provide the closure that victims’ families seek (Lithwick, 2006; Schieber, 2006).

There is disturbing evidence that executioners undergo a process of “moral disengagement,” or a kind of moral degradation (Osofsky et al., 2005). Executioners avoid self-condemnation by dehumanizing the convict, devaluing his or her life, and deflecting personal moral responsibility away from themselves by blaming juries, judges, governors, and “the law” for the prisoner’s execution, and not themselves.

Law
Do-not-resuscitate in the operating room

The courts unambiguously support the rights of competent patients to refuse life-sustaining interventions and to have treatment refusals honored while they are unconscious (In the Matter of Quinlan, 1976; Barber v. Superior Court, 1983; Cruzan v. Director MDH, 1990). Because anesthetic care usually interferes with a patient’s ability to make and express decisions, courts have found that anesthesiologists have legal obligations to protect the patient in the OR from unwanted intrusions (Schloendorff v. Society of New York Hospital, 1914; Kroll, 1992). Recently, physicians have been found liable when an unwanted resuscitation resulted in survival but significant morbidity (Anderson v. St. Francis–St. George Hospital, Inc., 1996; Osgood v. Genesys Regional Medical Center, 1997).

Physician participation in executions

In the USA, persons who participate in legally sanctioned executions are protected from criminal charges or civil penalties. In almost all cases, anonymity is promised to participants, making it difficult to know exactly how many executions are carried out with the help of physicians. Although lethal injection was developed as a “humane” method of execution, reports of complications and undue suffering of prisoners has called the constitutionality of lethal injection into question. Several state courts have recently ruled that lethal injection must be carried out under the supervision of a physician. In the state of Missouri, a court has ruled that an anesthesiologist must mix and personally administer the drugs, or supervise their administration (Michael Anthony Taylor v. Larry Crawford et al., 2006). Physicians are not legally compelled, however, to participate in the execution of prisoners.

Policy
Do-not-resuscitate in the operating room

Automatic suspension of DNR orders in the OR does not appropriately recognize patient rights to refuse medical therapies during the perioperative period. Guidelines established by the American Society of Anesthesiologists (1993), the American College of Surgeons (1994), the Association of Operating Room Nurses (Murphy, 1993), and the Joint Commission on Accreditation of Health Care Organizations (1996) require that DNR orders be rediscussed in the setting of surgery and anesthesia and state that automatic suspension of DNR orders in the perioperative setting is unethical. Discussion of DNR orders in patients undergoing anesthesia and surgery should include an explanation of the risks and benefits, including the more favorable outcomes for CPR in the OR, and the medical staff should document either the patient’s goals for treatment or specific treatments the patient refuses or accepts.

Physician participation in executions

In the USA, physician organizations have consistently held that physician participation in executions is unethical (American Medical Association, 2000; American Psychiatric Association, 2003). However, there are no reported cases of disciplinary action against a physician or expulsion from a professional society for such involvement. In part, anonymity provided to executioners prevents many professional organizations from even being able to identify which, or how many, of their members aid in executions.

Physician involvement in euthanasia and executions concerns anesthesiologists in particular; to the uninformed, their skills appear to make them ideal candidates for duties that involve killing (Jonsen, 1993; Truog and Berde, 1993). The American Society of Anesthesiologists (ASA) has, therefore, addressed the issue in several ways. The ethical guidelines of the society specifically support those of the American Medical Association, which prohibit physician involvement in executions (American Medical Association, 2000; American Society of Anesthesiologists, 2003). A statement by the President of the American Society of Anesthesiologists in 2006 (Guidry, 2006) concluded that, “physicians should not participate in executions, either by direct action or by performing ancillary functions. This includes making recommendations about drugs to be used. Physicians are healers, not executioners. The doctor–patient relationship depends upon the inviolate principle that a doctor uses his or her medical expertise only for the benefit of patients.”

How should I approach anesthesiology ethics in practice?


Do-not-resuscitate in the operating room

The favorable prognosis for resuscitation in the OR obligates anesthesiologists to revisit DNR orders with patients in the perioperative period, because the patient may make a different decision in the specific setting of surgery. Presenting a patient with an exhaustive “consent check list” of possible invasive or resuscitation measures, however, can be intimidating, confusing, and coercive at a time of significant stress. Some authors have, therefore, suggested a “goals-directed” approach to DNR in the OR that focuses on patient desires regarding outcomes rather than on specific techniques to try to meet those desires (Jackson and Van Norman, 1999; Truog et al., 1999). The patient may agree to have obvious, reversible problems addressed in a medically appropriate fashion but wish withdrawal of life support after surgery if other complications arise.

There is probably no single “best” way of approaching the patients with DNR orders who are scheduled for surgery. The process of informed consent and refusal depends on individual patient–provider relationships and conversations (Jackson and Van Norman, 1999). By the same token, DNR orders do not constitute permission to stop “caring” for the patient in other ways. Invasive monitoring, for example, may help the anesthesiologist to prevent the cardiac arrest that cannot subsequently be treated.

Physician participation in executions

Current ethical standards of most medical professional organizations either explicitly prohibit or discourage the involvement of physicians in the execution process, although such standards are often vague as to what constitutes “participation.” Most organizations appear to define participation as being present during executions, directing medical procedures involved in the execution, and prescribing further measures when the prisoner does not immediately die. The appropriateness of physician participation in declaring death (which may indirectly lead the physician to “prescribe” further measures if death has not resulted), or formulating methods of execution or recipes for lethal injection, remains controversial. In recent statements from the American Society of Anesthesiologists, however, involvement in such “ancillary” aspects of lethal injection is also discouraged (Guidry, 2006).

Although it is tempting to believe that physician participation in executions is somehow “merciful” or “beneficial,” such activities nevertheless cause tremendous harms, both to persons involved and to the medical profession at large. Physicians should, therefore, not participate in executions.

The cases

The first case considers a do not resuscitate order in the operating room. Mrs. C was competent to refuse life-saving therapy. She was at moderate risk for cardiac arrest in the OR. It became obvious through discussion that she hoped to survive her surgery, obtain relief from pain caused by the bowel obstruction, and rejoin her family. She wished to avoid prolonged mechanical ventilation, particularly if things appeared “hopeless.” She did not see any purpose in resuscitation if her heart stopped beating during surgery, but expected medications to be administered to “prevent it from stopping,” if possible. Despite her surgeon’s objections, the anesthesiologist placed invasive monitoring lines to facilitate hemodynamic management and reduce the risks of cardiac arrest in the OR. He also planned placement of the patient in the intensive care unit postoperatively. During the surgery, dopamine was initiated to support blood pressure and cardiac output. She remained mechanically ventilated postoperatively. Dopamine was gradually weaned and she was extubated on the third postoperative day. After 10 days in the hospital, she was discharged to a nursing facility, and returned home to her family two weeks later. She died at home after four months from the effects of metastatic cancer.

The second case deals with an execution. Despite a court order that lethal injection could only be carried out if a physician was present to supervise the execution, no physician could be found who agreed to participate. In February of 2006, executions by lethal injection in the state of Missouri were placed on an indeterminate “stay” until the issues could be resolved. Mr. D remains on death row awaiting execution.

REFERENCES

Abella, B. S., Alverado, J. P., Myklebust, H., et al. (2005). Quality of cardiopulmonary resuscitation during in-hospital cardiac arrest. JAMA 293: 305–10.
Adler, N. and Mueller, G. O. (1992). Psychiatry under tyranny: a report on the political abuse of Romanian psychiatry during the Ceausescu years. Curr Psychol 12: 3–17.
American College of Surgeons (1994). Statement of the American College of Surgeons on Advance Directives by Patients. “Do not resuscitate” in the operating room. Bull Am Coll Surg 79: 29.
American Medical Association (2000). AMA Opinion 2.06 Capital Punishment. Chicago, IL: American Medical Association.
American Psychiatric Association (2003). The Principles of Medical Ethics with Annotations Especially Applicable to Psychiatry, Section 1, No. 4. Arlington, VA: American Psychiatric Press.
American Society of Anesthesiologists (1993). Ethical Guidelines for the Anesthesia Care of Patients with Do-Not-Resuscitate Orders, Park Ridge, IL: American Society of Anesthesiologists [amended 2001].
American Society of Anesthesiologists (2003). Guidelines for the Ethical Practices of Anesthesiology. Park Ridge, IL: American Society of Anesthesiologists.
Anderson v. St. Francis–St. George Hospital, Inc. (1996) 617 N.E. 2nd 225 Ohio.
Baldus, D. and Woodworth, G. (1997). Race Discrimination in America’s Capital Punishment System since Furman v. Georgia (1972): The Evidence of Race Disparities and the Record of our Courts and Legislatures in Addressing this Issue. Chicago, IL: American Bar Association.
Barber v. Superior Court (1983) 147 Cal App 3d 1006, 195 Cal Rptr 484, 491.
Baum, K. (2001). “To comfort always”: physician participation in executions. J Legisl Pub Policy 5: 47–82.
Berk, R. (2005). New Claims about Executions and General Deterrence: Deja Vu All Over Again? Los Angeles, CA: University of California Press.
Blume, J. (2005). Killing the willing: “volunteers,” suicide and competency. Michigan Law Rev 103: 939–71.
Brindley, P. G., Markland, D. M., Mayers, F., and Kutsogiannis, D. J. (2002). Predictors of survival following in-hospital adult cardiopulmonary resuscitation. CMAJ 167: 343–8.
Casarett, D. and Ross, L. F. (1997). Overriding a patient’s refusal of treatment after an iatrogenic complication. N Engl J Med 336: 1908–10.
Casarett, D. J., Stocking, C. B., and Siegler, M. (1999). Would physicians override a do-not-resuscitate order when a cardiac arrest is iatrogenic? J Gen Intern Med 14: 35–8.
Clark, P. A. (2006). Physician participation in executions: care giver or executioner? J Law Med Ethics 34: 95–104.
Clemency, M. V. and Thompson, N. J. (1993). “Do not resuscitate” (DNR) orders and the anesthesiologist: a survey. Anesth Analg 76: 394–401.
Clemency, M. V. and Thompson, N. J. (1994). “Do not resuscitate” (DNR) orders in the perioperative period: a comparison of the perspectives of anesthesiologists, internists, and surgeons. Anesth Analg 78: 651–8.
Cook, P. J. and Slawson, D. B. (1992). The Costs of Processing Murder Cases in North Carolina. Durham, NC: Terry Sanford Institute of Public Policy, Duke University.
Cruzan v. Director, MDH (1990) 497 US 261 US Supreme Court.
Dieter, R. C. (1992). Millions Misspent: What Politicians Don’t Say About the High Costs of the Death Penalty, Washington, DC: Death Penalty Information Center.
Dieter, R. C. (2004). Innocence: A Death Penalty Information Center Report. Washington, DC: Death Penalty Information Center.
Forsberg, M. (2005). Money for Nothing? The Financial Cost of New Jersey’s Death Penalty, Trenton, NM: New Jersey Policy Perspective.
Gluzman, S. F. (1991). Abuse of psychiatry: analysis of the guilt of medical personnel. J Med Ethics 17: 19–20.
Gross, S., Jacoby, K., Matheson, D. J., Montgomery, N., and Patil, S. (2005). Exonerations in the United States 1989 through 2003. J Crim Law Criminol 95: 523–37.
Guidry, O. F. (2006). Message from the President; Observations Regarding Lethal Injection. Highland, Park, IL: American Society of Anesthesiologists.
Hastings Center (1996). The goals of medicine. Setting new priorities: mistaken medical goals and the misuse of medical knowledge. Hastings Cent Rep 26: S1–27.
Hinman, F. (1944). Euthanasia. J Nerv Ment Dis 99: 640.
In the Matter of Quinlan (1976) 70 NJ 10, 355 A.2d.647 Supreme Court of New Jersey.
Jackson, S. H. and Van Norman, G. A. (1999). Goals- and values-directed approach to informed consent in the “DNR” patient presenting for surgery: more demanding of the anesthesiologist? Anesthesiology 90: 3–6.
Joint Commission on Accreditation of Health Care Organizations (1996). Comprehensive Accreditation Manual for Hospitals: Advanced Directives. Oakbrook Terrace, IL: Joint Commission on Accreditation of Health Care Organizations.
Jonsen, A. R. (1993). To help the dying die: a new duty for anesthesiologists? Anesthesiology 78: 225–8.
Khan, A. and Leventhal, R. M. (2002). Medical aspects of capital punishment executions. J Forensic Sci 47: 847–51.
Koniaris, L. G., Zimmers, T. A., Lubarsky, D. A., and Sheldon, J. P. (2005). Inadequate anaesthesia in lethal injection for execution. Lancet 365: 1412–14.
Kroll, D. A. (1992). Professional Liability and the Anesthesiologist. Park Ridge, IL: American Society of Anesthesiologists.
Langer, G. (2001). Death Penalty Ambivalence; Polls Point to Support for Execution Moratorium in US. Philadelphia, PA: International Communications Research, Media.
Lithwick, D. (2006). Does killing really give closure? Washington Post. 24 March, Bo3.
Michael Anthony Taylor v. Larry Crawford et al. (2006). United States District Court Western District of Missouri, Central Division 2:05–cv–04173–FJG, June 26.
Murphy, E. K. (1993). Do-not-resuscitate orders in the OR. AORN J 58: 399–401.
Myrianthefs, P., Kalafati, M., Lemonidou, C., et al., (2003). Efficacy of CPR in a general, adult ICU. Resuscitation 57: 43–8.
Nuremberg Code (1949). Trials of War Criminals before the Nuremberg Military Tribunals under Control Council Law No. 10, Vol. 2, Washington, DC: US Government Printing Office, pp. 181–2 (http://www.hhs.gov/ohrp/references/nurcode.htm).
Olsson, G. and Hallen, B. (1988). Cardiac arrest during anaesthesia. A computer-aided study in 250 543 anesthetics. Acta Anaesthesiol Scand 32: 653.
Osgood v. Genesys Regional Medical Center (1997), No. 94–267331–NH Circuit Court for Genesee County.
Osofsky, M. J. and Osofsky, H. J. (2002). The psychological experience of security officers who work with executions. Psychiatry 65: 358–70.
Osofsky, M. J., Bandura, A., and Zimbardo, P. G. (2005). The role of moral disengagement in the execution process. Law Hum Behav 29: 371–93.
Pellegrino, E. D. (1993). Societal duty and moral complicity: the physician’s dilemma of divided loyalty. Int J Law Psychiatry 16: 371–91.
Pellegrino, E. D. and Thomasma, D. C. (2000). Dubious premises – evil conclusions: moral reasoning at the Nuremberg trials. Camb Q Healthc Ethics 9: 261–274.
Reis, A. G., Nadkarni, V., Perondi, M. B., Grist, S., and Berg, R. A. (2002). A prospective investigation into the epidemiology of in-hospital pediatric cardiopulmonary resuscitation using the international Utstein reporting style. Pediatrics 109: 200–9.
Rood V. (1979). Soviet abuse of psychiatric commitment: an international human rights issue. Calif West Int Law J 9: 629–53.
Rosenfeld, R. (2004). The case of the unsolved crime decline. Sci Am.
Ross, L. F. (2003). Do not resuscitate orders and iatrogenic arrest during dialysis: should “no” mean “no”? Semin Dial 16: 395–8.
Schieber, V. (2006). Testimony to the Subcommittee on the Constitution, Civil Rights and Property Rights. Washington, DC: US Senate Committee on the Judiciary.
Schloendorff v. Society of New York Hospital (1914) 211 NY 125; 105 N.E. 92 Court of Appeals of New York.
Sikora, A. and Fleischman, A. R. (1999). Physician participation in capital punishment: a question of professional integrity. J Urban Health 76: 400–8.
Silver, G. (1986). Whom do we serve? Lancet i: 315–16.
Sorensen, J., Wrinkle, R., Brewer, V., and Marquart, J. (1999). Capital punishment and deterrence: examining the effect of executions on murder in Texas. Crime Delinquency 45: 481–93.
Sprung, J., Warner, M. E., Contreras, M. G., et al., (2003). Predictors of survival following cardiac arrest in patients undergoing noncardiac surgery: a study of 518 294 patients at a tertiary referral center. Anesthesiology 99: 259–69.
SUPPORT Principle Investigators (1995). A controlled trial to improve care for seriously ill hospitalized patients. The Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments (SUPPORT). JAMA 274: 1591–8.
Thorburn, K. M. (1987). Physicians and the death penalty. W J Med 146: 638–40.
Truog, R. D. and Berde, C. B. (1993). Pain, euthanasia, and anesthesiologists. Anesthesiology 78: 353–60.
Truog, R. D., Waisel, D., and Burns, J. P. (1999). DNR in the OR: a goal–directed approach. Anesthesiology 90: 289–95.
UN (1949). Geneva Convention Relative to the Treatment of Prisoners of War. [Adopted on 12 August 1949 by the Diplomatic Conference for the Establishment of International Conventions for the Protection of Victims of War, held in Geneva from 21 April to 12 August, 1949. Entry into force 21 October 1950.] Geneva: Office of the United Nations High Commissioner for Human Rights, pp. 1997–2002.
US Department of Justice (2003). Uniform Crime Reports; January to December, 2002. Washington, US Department of Justice, Federal Bureau of Investigation.
US Senate (2005). The Streamlined Procedures Act of 2005, S.1088. United States Senate, 109th Cong., 1st Session.
van Es, A. (1992). Medicine and torture. BMJ 305: 380–1.
Walker, R. M. (1991). DNR in the OR. Resuscitation as an operative risk. JAMA 266: 2407–12.
Wenger, N. S., Greengold, N. L., Oye, R. K., (1997). Patients with DNR orders in the operating room: surgery, resuscitation, and outcomes. SUPPORT Investigators. J Clin Ethics 8: 250–7.
Zandbergen, E. G., de Haan, R. J., Reitsma, J. B., and Hijdra, A. (2003). Survival and recovery of consciousness in anoxic–ischemic coma after cardiopulmonary resuscitation. Intens Care Med 29: 1911–15.