Mitochondria and the Future of Medicine · the Key to Understanding Disease, Chronic Illness, Aging, and Life Itself by Know, Lee -- Read -- Imperial Library of Trantor

Index

CONTENTS CHAPTER ONE: The Force: The Origins and Evolution of Mitochondria in Human Physiology

Let’s Review Some Cell Biology The Evolution of the Eukaryotic Cell Mitochondria: They Are the Force The Basics of Mitochondria The Basics of Cellular Respiration and Oxidative Phosphorylation A Game of Hot Potato: The Electron Transport Chain (ETC) ATP Synthase: Coupling the ETC with Oxidative Phosphorylation Mitochondrial DNA: A Curious Relic of Ancient History A Radical Signal: The Positive Side of Free Radicals Mitochondrial Mutations: The Beginning of the End Discarded Theories of Aging The Mitochondrial Theory of Aging Extending Maximum Life Span in Mammals Degenerative Diseases and the Eventual End It’s Getting Hot in Here: Uncoupling the Proton Gradient

A Review of Bioenergetics Food and Oxygen: The Ingredients for Producing Energy ATP Production and Turnover The Role of Mitochondria in Cardiovascular Disease The Role of Mitochondria in the Nervous System, Brain, and Cognitive Health Mitochondrial Involvement in Neurodegeneration Depression Attention-Deficit/Hyperactivity Disorder: Pay Attention to the Mitochondria Chronic Fatigue Syndrome, Myalgic Encephalomyelitis, and Fibromyalgia Type 2 Diabetes Mitochondrial Diabetes Medication-Induced Mitochondrial Damage and Disease Mitochondrial Disease When Mitochondrial Disease Is the Primary Disease Treating Mitochondrial Disease Age-Related Hearing Loss Mitochondria, Aging Skin, and Wrinkles Infertility and Mitochondria Eye-Related Diseases Stem Cells Require Healthy Mitochondria Cancers: Understanding the Causes Brings Us One Step Closer to Cures Aging as a Disease

How Do the Birds Do It? D-Ribose Pyrroloquinoline Quinone (PQQ) Coenzyme Q10 L-Carnitine Magnesium Alpha-Lipoic Acid Creatine B Vitamins Iron Resveratrol and Pterostilbene Ketogenic Diets and Calorie Restriction Massage and Hydrotherapy Cannabis and Phytocannabinoids Exercise and Physical Activity Pulling It All Together

ACKNOWLEDGMENTS GLOSSARY BIBLIOGRAPHY FIGURE CREDITS ABOUT THE AUTHOR