CHAPTER 23 AROMATHERAPY
The versatile nature of essential oils leads to a wide range of potential uses, and their therapeutic value is being harnessed, evaluated, and appreciated in a number of health care settings worldwide. This chapter explores the use of essential oils and aromatherapy with particular reference to clinical practice. By the end of the chapter, the reader will have a global overview of the potential of essential oils as therapeutic agents as well as an appreciation of the particular benefits and challenges of using these powerful substances in clinical environments.
Modern-day aromatherapy has origins spanning sacred and ritual use, perfumery, aesthetics, and medical applications, and these aspects continue to be relevant today when we consider the psychophysiological benefits that essential oils bring to the therapeutic encounter. For a historical overview of the therapy the reader can refer to specialist aromatherapy texts and articles that include accounts of the history and development of modern British aromatherapy by Bensouilah (2005) and Harris (2003) and the development of aromatherapy in the United States by Buckle (2003a, 2003b). This chapter focuses on the current situation and future potential of this versatile therapy.
Aromatherapy may be defined as the selected use of essential oils and related products of plant origin with the general goal of improving health and well-being. The word aromatherapie was first used in 1937 by the French perfumer and chemist René Maurice Gattefossé (1881-1950), who, along with pioneers Jean Valnet (1920-1995) and Marguerite Maury (1895-1968), is largely credited with the modern revival of interest in the use of essential oils for therapeutic purposes.
In modern-day aromatherapy, the therapist uses these fragrant and active substances to affect the body-mind via a number of administration methods (external, inhalational, internal), usually in dilution and with a focus on a holistic approach to health in cooperation with the patient or client. The concept of the “individual prescription” as stressed by Maury in her seminal work Secret of Life and Youth: Regeneration Through Essential Oils—A Modern Alchemy (1964) (originally published in 1961 in French as La capitale jeunesse) remains key in contemporary aromatherapy practice.
Essential oils are the main active tools of aromatherapy. These highly concentrated and fragrant substances of plant origin have a complex chemical composition, the totality of which determines the essential oil’s aroma and therapeutic potential. The concept of the “whole oil” as opposed to one that has been rectified, concentrated by deterpenation, or otherwise chemically altered is fundamental to most aromatherapists, who believe that there is an inherent synergy between the chemical components that needs to be preserved as much as possible. This concept does have some weight behind it, at least in terms of antimicrobial and antiinflammatory effects, because a number of studies have demonstrated synergy between main active components and minor, less active components in an individual essential oil (Harris, 2002), similar to the observed synergic effects of herbal remedies taken internally.
Essential oils themselves are clearly defined by the industry that uses them. The International Organization for Standardization (ISO) defines them as follows:
Products obtained from natural raw materials by distillation with water or steam or from the epicarp of citrus fruits by a mechanical process or by dry distillation. The essential oil is subsequently separated from the aqueous phase by physical means.
This criterion sets essential oils apart from other plant extracts, such as those produced with solvents (e.g., hexane or supercritical fluid extraction), which can have quite different chemical compositions and organoleptic properties (Kotnik et al, 2007; Pourmortazavi et al, 2007). These differences mean that the therapeutic effects of these two types of extracts cannot always be compared. Newer advanced technology, however, such as microwave hydrodiffusion with gravity, offers the potential for new extraction methods that yield products of composition similar to that obtained with distillation (Vian et al, 2008), while economizing on time and energy for extraction.
While aromatherapists use predominantly essential oils as defined earlier, they may also use aromatic extracts (e.g., absolutes, resinoids, carbon dioxide extracts), because these products often have a fragrance that is very close to that of the original plant. These extracts are thus frequently used more to confer fragrance benefits than to produce specific physiological or pharmacological benefits.
Other related natural products at the aromatherapist’s disposal include the following:
Over the past 20 years as the use of essential oils has grown in popularity and potential, their versatility has led to different styles of aromatherapy, the main ones of which are shown in Figure 23-1. As can be seen, the aromatic medicine style is usually considered to be a branch of herbal medicine rather than purely associated with aromatherapy as it is most commonly perceived.
Holistic aromatherapy usually combines essential oils with body massage (see Chapters 16 and 17), and this application remains the main form of aromatherapy as taught and practiced worldwide, with at least 6000 aromatherapists practicing in the United Kingdom alone (Walker et al, 2002). Characteristics of this form of aromatherapy include the following:
A profile of the average aromatherapist was compiled from a U.K.-based survey conducted in 2001 (Osborn et al). Obviously these trends are not necessarily representative of all countries where aromatherapy is practiced, but in the author’s opinion they do reflect an international profile of holistic-style aromatherapists. Key profile points include the following:
As can be seen in Figure 23-1, aromatic medicine, or medical aromatherapy, has its origins in phytotherapy and largely arises, is taught, and is practiced in European countries such as Germany and France where only those who are licensed medical professionals are legally permitted to practice. This more intensive and often internal use of essential oils is now being increasingly taught and practiced in other countries such as the United Kingdom where there may be greater freedom to practice by nonlicensed medical professionals such as herbalists, traditional Chinese medicine practitioners, and practitioners of aromatic medicine (these are usually qualified aromatherapists who have pursued supplementary training in this discipline). This style of aromatherapy is characterized by the following:
A profile of the medical aromatherapist has not yet been determined, but because of the more allopathic approach, it is hardly surprising that trends resemble those among orthodox practitioners, especially in terms of gender. Having worked closely with medical aromatherapists over a number of years, the author has the following observations.
When essential oils are integrated into medical environments to address particular patient challenges alongside mainstream care, the practice is often termed clinical aromatherapy. It effectively represents a merging of both holistic and medical styles that are adapted to individual needs. While most interventions in medical environments still tend toward use of the lower-dose and external and inhalational methods, as in holistic aromatherapy, there is an increasing trend toward and acceptance of using more intensive interventions where necessary for particular clinical challenges, such as pain management, malodor control, wound care, oral care, and treatment of infection. This style of aromatherapy is characterized by the following:
The development of essential oil use in the clinical environment was and remains largely nurse driven, although in many settings it is not a prerequisite that the practitioner be medically qualified (e.g., nurse, midwife); indeed, many aromatherapists working in hospitals and hospice settings are not nurses. They are often qualified therapists who have a good understanding of pathology and experience in their specialist area. For example, before working in the cancer care or hospice setting, aromatherapists often pursue supplementary training to prepare them specifically for this field. A range of specialist texts and articles exist for clinical aromatherapy integration (Buckle, 2003a, 2000b; Dunning, 2007; Price et al, 2007; Smith et al, 2008; Tiran, 2000).
As yet there has been no survey of clinical aromatherapists, but based on the author’s experience in working and training in this style, a typical profile becomes apparent:
Aesthetic aromatherapy has its origins in the Anglo-Saxon holistic style of aromatherapy in which pioneers of the art and science of aromatherapy such as Marguerite Maury explored the cosmetic benefits of essential oils combined with the whole aromatherapy experience, including massage. Today, work in the research and development departments of many leading cosmetic companies has led to the inclusion of essential oils in cosmetic products as active agents, and research exists to confirm the role of essential oils in skin care. Because of financial rivalry, results of cosmetic research conducted by leading companies are not widely diffused in the professional literature. What has been published confirms the valuable role of essential oils in dermatology (Denda et al, 2000; Hosoi et al, 2000; Monges et al, 1994; Mori et al, 2002), and one specialist aromatherapy text now exists for this field (Bensouilah et al, 2006).
The surge in popularity of the spa movement has also led to aromatherapy’s being offered for well-being and cosmetic benefit. Many therapists training for the spa setting receive rudimentary instruction in aromatherapy along with other spa techniques and often use preblended commercial products rather than providing individualized care. It is also now common for basic aromatherapy training to be included in aesthetician’s training programs.
Although the main styles of aromatherapy have been detailed earlier, there can be significant variations and, depending on the country in which each method has evolved, differences in technique and application. For example, while in the United Kingdom aromatherapy training and practice almost invariably include massage, in the United States (due to massage licensing laws, which can vary among states) often holistic aromatherapists are not massage practitioners, working instead with custom blends of essential oils that are then promoted for use in self-care. In addition, the various aromatherapy styles show significant interdependence, with holistic care usually at the core of all the styles (Figure 23-2).
It is also apparent from the earlier discussion that the main styles of aromatherapy may have different training requirements; however, the reality is that, although training provision is well structured for holistic aromatherapy, with minimum standards already established in a number of countries, training in clinical and medical styles is less well recognized and standards are not consistent internationally. For example, in France, training in the medical aromatherapy style that is aimed at medical professionals is extremely variable in duration and content. A recent bold move in Australia is the establishment of national training standards and competencies for aromatic medicine as separate from aromatherapy (available through http://www.NTIS.gov.au); it is the first such move in the world, and it is anticipated that other countries will respond in a similar fashion in the future.
There is a wealth of research to support the therapeutic value of essential oils, and in recent years this evidence has become increasingly disseminated and accessible in professional publications. The immense psychophysiological potential of essential oils is due to two or three factors.
1. Essential oils are fragrant substances. Thus they are able to impact the body-mind via the olfactory sense, with all its deep-seated limbic and higher brain connections that influence, among other things, emotions, memory, desire, basic drive, and hormonal response. The olfactory neurons travel directly to the frontal portions of the brain. For these reasons, inhalation of essential oil fragrance is considered a key aspect of an aromatherapy treatment.
The capacity of fragrant substances to influence emotions and behavior has led to the field of Aroma-Chology as defined by the Sense of Smell Institute (formerly the Olfactory Research Fund; http://www.senseofsmell.org) in 1989. This field is dedicated to the study of measurable effects of the interrelationships between psychology and fragrance technology and is not restricted to essential oils and naturally derived aromatics. However, there is a significant overlap between Aroma-Chology and aromatherapy, with aromatherapists going a step further to seek physiological benefits of essential oils, either indirectly via the olfactory sense or more directly through their absorption and pharmacological activity. A recent systematic review addressing the psychophysiological effects (on mood, cognition, behavior, performance, physiology) of fragrant substances (Herz, 2009) confirms that they can significantly impact the body-mind via inhalation.
Aromatherapists use these confirmed mood-enhancing benefits of fragrance to reduce stress and thereby improve general health and well-being. However, these effects are largely influenced by context, expectation, prior experience of the aroma, its concentration when presented, and perception of the fragrance as pleasant or unpleasant. Indeed, it may be possible that psychological effects can override the potential physiological properties of an essential oil (Moss et al, 2006; Robbins et al, 2007). This may explain the inconsistencies that are sometimes found when attempts are made to measure the effects of individual essential oils on the body-mind (Neale et al, 2008). There is nevertheless supportive evidence for the positive and measurable effects of aromatherapy in relieving stress and anxiety and promoting well-being over a range of administration methods and evaluation tools (Atsumi et al, 2007; Cooke et al, 2000; Morris, 2008; Saeki, 2000).
2. Essential oils are pharmacologically active. Their chemical components are secondary metabolites produced by the plant predominantly for defensive purposes, and they are thus biologically active substances. Because of their lipophilic nature and small molecular size, many components of essential oils are able to penetrate the body irrespective of their route of administration and exert a pharmacological impact either locally (in the tissues surrounding their application site) or systemically (via the bloodstream). For these reasons, essential oils are often administered via different routes according to the needs of the individual. The capacity of essential oil components to enter the bloodstream via different routes has been studied, at least for inhalation (Buchbauer et al, 1991; Jager et al, 1996; Stimpfl et al, 1995) and topical administration (Fewell et al, 2007; Fuchs et al, 1997; Jager et al, 1992), and pharmacological effects are confirmed via ingestion for a range of pathologies (Goerg et al, 2003; Juergens et al, 2003; Kerhl et al, 2004). Because of the increased physical and metabolic barriers at the skin interface (stratum corneum, especially) compared with other routes of administration, this route is likely to result in extremely low (but nonnegligible) amounts of active components’ reaching the bloodstream.
Assuming therefore that some essential oil components are able to enter the tissues locally and/or enter the bloodstream, there are a number of pharmacological possibilities. The main actions are listed in Table 23-1.
Action | Research studies (not exhaustive) |
---|---|
Analgesic | Yip et al, 2008 (ginger and orange) Le Faou et al, 2005 Greenway et al, 2003 (geranium) |
Antibacterial | Cermelli et al, 2008 Enshaieh et al, 2007 Dryden et al, 2004 |
Antifungal | Sokovi´c et al, 2008 Khosravi et al, 2008 Jirovetz et al, 2007 |
Antiinflammatory | Chao et al, 2008 (cinnamaldehyde) Lee et al, 2007 Ghazanfari et al, 2006 |
Antioxidant | Singh et al, 2008 Chung et al, 2007 Zhang et al, 2006 |
Antiparasitic | Navarro et al, 2008 Scanni et al, 2006 Oladimeji et al, 2005 |
Antispasmodic | Goornemann et al, 2008 Grigoleit et al, 2005 Jahromi et al, 2003 |
Antiviral | Schnitzler et al, 2008 Schnitzler et al, 2007 Giraud-Robert, 2005 |
Carminative | Alexandrovich et al, 2003 Goerg et al, 2003 |
Cicatrisant | Amanlou et al, 2007 Orafidiya et al, 2005 Orafidiya et al, 2003 |
Deodorizing | Warnke et al, 2006 Mercier et al, 2005 Sherry et al, 2003 |
Immune stimulating | Nam et al, 2008 Serafino et al, 2008 Mikhaeil et al, 2003 |
Mucolytic and expectorant | Fenu et al, 2008 Kehrl et al, 2004 Mattys et al, 2000 |
Rubefacient | Xu et al, 2006 Hong et al, 1991 Green et al, 1989 |
Sedative | Moss et al, 2006 Lim et al, 2005 Koo et al, 2003 |
In addition to the aforementioned fragrance and pharmacological factors, many aromatherapists would add the following third dimension to essential oil therapeutics.
3. Essential oils are able to impact the individual at a subtle or vibrational level. Many therapists refer to essential oils as the “life force” of the plant and believe that their vibrational energetic qualities are able to influence the individual on a subtle level. Thus practitioners of different forms of energy medicine such as traditional Chinese and Ayurvedic medicines may use essential oils as part of their therapy and select these remedies according to energetic principles. A number of aromatherapy texts support these energetic approaches (Holmes, 2007, 2008; Miller et al, 1995; Mojay, 1996). While it is as yet hard to find credible and reproducible evidence for the energetic-vibrational impact of essential oils, as has been previously seen, the impact of fragrance on the body-mind as well as the pharmacological activity of essential oils has been well studied. The vibrational energies of different flowering plants have been developed to offer their own forms of therapy, as with the Bach flower remedies, for example.
How the effectiveness of aromatherapy is assessed and reported in the literature is highly variable, ranging from single case study reports and evidence-based articles in professional publications to surveys of service provision, audits, and full-scale clinical trials. A review of the literature demonstrates that the last 10 years have witnessed an increase in both the number and quality of documented benefits of aromatherapy integration into the clinical environment. The challenge always remains of how to evaluate successfully the benefits of what is in fact a multifaceted therapy that typically combines fragrance (aroma) with touch (typically with massage), potential pharmacological activity (chemical components), individualized care, and positive client-therapist interaction. For these reasons it is not surprising that some still question the validity of many aromatherapy interventions (e.g., Cooke et al, 2000). Wherever possible, this chapter reports on recent work and research and focuses mainly on human studies.
Aromatherapy is increasingly integrated into a wide range of health care settings. These are summarized (not in order of prevalence) in Box 23-1.
BOX 23-1 Examples of Health Care Areas into Which Aromatherapy Is Being Integrated
AIDS, Acquired immunodeficiency syndrome; HIV, human immunodeficiency virus.
To provide concrete examples of where and how aromatherapy is increasingly integrated, the following sections outline five of these clinical areas in more detail:
The holistic and clinical styles of aromatherapy have been used in pregnancy care and midwifery for many years, assisting the mother-to-be predominantly in stress and anxiety management but also providing relief with common pregnancy-associated symptoms such as nausea, skin changes, altered sleep patterns, pain, and fatigue. In the labor environment, essential oils are most often administered by midwife-aromatherapists, whereas preconception, antenatal, and postnatal aromatherapy care is often provided by nonmidwife aromatherapists and doulas.
The accidental or deliberate misuse of essential oils can pose a risk to the unborn child (Anderson et al, 1996; Weiss, 1973); however, so far no reports have been published of pregnancy-related risk when the holistic style of aromatherapy is used, although some have labelled aromatherapy provision by nonmidwives as “an accident waiting to happen” (Tiran, 1996). This issue of safety is a hotly debated topic in the midwifery field, and opinions differ as to what dosages should be employed and which essential oils are safe or hazardous in pregnancy. These discrepancies are due to lack of reporting of adverse effects, and thus risk assessment is based on prediction, speculation, and each practitioner’s individual experience in this field. A few essential oil components such as sabinyl acetate have been confirmed as potentially hazardous to fetal development in animal studies (Pages et al, 1996); however, these components are not found in the essential oils commonly used in holistic aromatherapy.
Providing stress reduction during labor has multiple benefits for both mother and baby. These include less need for mechanical intervention and opioid analgesia, reduced use of epidural anesthesia, improved mobility during labor, and generally increased control over the labor process, all of which may contribute to a safer birthing process and a more alert baby (Bastard et al, 2006; Burns, 2005; Burns et al, 2000, 2007; Fanner, 2005; Simkin et al, 2007).
In the postnatal period, benefits can also be seen, including improved psychological status, improved bonding, and increased coping skills (Antoniak, 2008; Imura et al, 2006; Meyer, 2005).
Along with the favorable effects of aromatherapy in midwifery, its benefits in oncology and palliative care environments are increasingly well surveyed, documented, and researched. Aromatherapy is the most popular complementary therapy for persons with cancer in the United Kingdom. The predominant style used in this setting is holistic aromatherapy coupled with massage or light touch techniques, and the focus is mostly on anxiety reduction and promotion of well-being (Abel, 2000; Cawthorne et al, 2000; De Valois et al, 2001; Dyer, 2004; Imanishi et al, 2009; Peace et al, 2002; Stringer, 2000; Wilkinson et al, 1999). With regard to improvement in well-being and reduction of anxiety and fatigue, research shows that aromatherapy can offer significant benefit, at least in the short term, to persons with cancer and to their families and/or caregivers (Curry et al, 2008; Wilkinson et al, 2007). In some countries such as the United Kingdom clear guidelines have been established for the use of complementary therapies like aromatherapy in palliative care (Tavares, 2003).
A more recent development in oncology and palliative care is the increasing use of non–massage-associated clinical aromatherapy interventions with positive results for challenges such as nausea, fatigue, malodor, breathlessness, pain relief, wound management, skin care, and oral care (Dyer et al, 2008; Knevitt, 2004; Kohara et al, 2004; Louis et al, 2002; Mercier et al, 2005; Schwan, 2004; Warnke et al, 2006). These clinical interventions include the use of essential oils in the following:
Aromatherapy is a well-established treatment in elder care in various countries, particularly in residential care environments. Nursing home physicians are generally in favor of using nonpharmacological interventions for management of behavioral disturbances associated with dementia, but their level of knowledge is variable; this may restrict patient access to therapies such as aromatherapy (Cohen-Mansfield et al, 2008).
Benefits have been reported in working with individuals who have dementia/Alzheimer disease, including help in reducing agitation, modifying behavior, providing stimulation and social interaction, and assisting in orientation (Ballard et al, 2002; Holmes et al, 2002; MacMahon et al, 1998; Smallwood et al, 2001), although a recent Cochrane systematic review confirms that more sound research evidence is required in this area (Thorgrimsen et al, 2003). In some cases of severe dementia, aromatherapy massage interventions might actually lead to an increase in agitation (Brooker et al, 1997). Lavandula angustifolia (lavender) essential oil is one of the most commonly used essential oils for elderly populations (Bowles et al, 2005); the benefit of its inhalation in reducing dementia-related agitation in one Chinese crossover randomized trial has been confirmed (Lin et al, 2007). Another element of importance in this field is providing aromatherapy support for caregivers of persons with dementia, who themselves are subject to significant stress and decline in health (Henry, 2008).
Other benefits of aromatherapy in these settings include malodor control and potential reduction in need for medication (Berlie, 2008) as well as improvement in sleep patterns in the older patient (Cannard, 1996). A recent study demonstrates that odor stimuli such as those provided by essential oils—in this case Piper nigrum (black pepper) and Lavandula angustifolia (lavender)—may improve posture and balance in older persons (Freeman et al, 2009), who are more prone to falling, whereas odor stimuli such as black pepper and menthol can assist in improving the swallowing reflex (Ebihara, Ebihara, and Maruyama, 2006; Ebihara, Ebihara, and Watando, 2006).
Another aspect of aromatherapy care for this age group is the management of pain (especially chronic pain). Here there is evidence that aromatherapy can offer at least short-term assistance with pain management (Bensouilah, 2004; Bowles et al, 2005; Yip et al, 2008).
In the field of special needs, a number of aromatherapists work independently, and to the author’s knowledge, few clinical trials have been conducted in this domain. Therapists work with a range of patients with special needs, such as deaf and deaf-blind individuals (Armstrong et al, 2000), individuals with autism (Ellwood, 2008), and those with other mental health and special needs (Durell, 2002; Greenwood, 2008). One specialist text exists on aromatherapy for people with learning difficulties (Sanderson et al, 1991). Case reports, articles, and therapists’ experience in the special needs environment demonstrate real benefits of using essential oils, some of which are the following:
In most cases, therapy is given coupled with massage or other touch techniques and incorporates the use of other sensory stimuli. However, one crossover study examining four interventions (Snoezelen therapy, relaxation therapy, aromatherapy hand massage, and physical activity) did not find that the aromatherapy intervention was beneficial for improving alertness in individuals with profound learning disabilities (Lindsay et al, 1997).
As has already been shown, the benefits of fragrance on mood, cognition, and behavior are well established, and thus it is not surprising to find that aromatherapy is used widely in the care of persons with affective disorders and mental health issues. Indeed, olfactory impairment is associated with depressive behavior and occurs in the early stages of several central nervous system and neuropsychiatric diseases, such as depression, Parkinson disease, schizophrenia, Alzheimer disease, and multiple sclerosis (Atanasova et al, 2008; Moscavitch et al, 2009).
Self-care with essential oils to improve mood and well-being is common in the general population, and persons with mild to moderate depression and anxiety disorders are more likely to seek complementary therapies such as aromatherapy than are those with severe depression (Hsu et al, 2008). In addition to benefiting from simple self-care measures such as lavender baths for reducing anxiety (Morris, 2008), residents in short-term psychiatric care facilities may also profit from aromatherapy under the guidance of a qualified therapist, as reported by Kyle (2008).
Aromatherapy offers many benefits to the individual with psychiatric illness, including the following:
In psychiatry, the main benefits of essential oils come through their inhalation via diffusion or the use of scented products applied to the skin or added to baths, with massage conferring added psychophysiological benefit. Inhalation of a pleasantly perceived fragrance has confirmed benefits in humans in reducing symptoms of depression and improving general immune function (Komori et al, 1995).When coupled with other mind-oriented therapies such as counselling, relaxation therapy, or hypnotherapy, a form of “odor conditioning” can be used successfully to assist the person, particularly in the realm of stress and anxiety management. This application is well illustrated in the work of Spector et al (1993) on the use of odor cues to promote relaxation in the treatment of speech anxiety and in the work of Betts (2003) on reducing the incidence of epileptiform convulsions through association of fragrance with hypnosis.
In addition to the aforementioned benefits, which are largely due to the effects of a pleasant fragrance, there may also be pharmacological activity, which further increases sedative, anxiolytic, and mood-enhancing effects (Buchbauer et al, 1993). The degree of sedation achieved may be on a par with that produced by benzodiazepines or other hypnotic medications and indeed may assist with withdrawal from or reduction in dependence on these drugs (Hardy et al, 1995; Komori et al, 2006). Both traditional and scientific evidence exists supporting the use of Lavandula angustifolia (lavender) and Melissa officinalis (lemon balm) essential oils to benefit individuals with anxiety, depression, and psychotic disorders (Abuhamdah et al, 2008; Huang et al, 2008).
It can be seen from the foregoing discussion that aromatherapy is increasingly accepted and implemented alongside mainstream medical care for patients in a diverse range of settings. Many essential oils are used in therapy worldwide. The most common ones are listed in Box 23-2.
BOX 23-2 Twenty-Seven Essential Oils Commonly Used in Clinical Environments (Latin Name and Common Name)
Boswellia carterii, frankincense
Chamaemelum nobile, Roman chamomile
Citrus aurantium var. amara flos., neroli
Citrus aurantium var. amara fol., petitgrain
Cupressus sempervirens, cypress
Cymbopogon citratus, lemongrass
Cymbopogon martinii, palmarosa
Eucalyptus radiata, eucalyptus
Lavandula angustifolia, lavender
Lavandula latifolia, spike lavender
Matricaria recutita, German chamomile
Melaleuca alternifolia, tea tree
Origanum majorana, sweet marjoram
Pelargonium x asperum, geranium
Rosmarinus officinalis, rosemary
Potential benefits such as lowered perception of stress by staff and caregivers comprise another important area of aromatherapy provision (Curry et al, 2008; Pemberton et al, 2008; Tysoe, 2000). Because of the multifaceted nature of the therapy, it can be challenging to measure outcomes effectively, but there is now increasingly sound qualitative and quantitative evidence to encourage its continued use in specialty areas such as elder care and cancer and palliative care. It is always essential, however, to link efficacy with safety, and issues of safe practice are of paramount importance.
Essential oils, as concentrated active agents, have the capacity to cause harm if not used appropriately. Because of their widespread inclusion in foods, flavorings, fragrances, and cosmetics, many have been rigorously assessed for their potential hazards, and guidelines exist for safe levels of their inclusion in these products, such as the code of practice and guidelines established by the International Fragrance Association (http://www.ifraorg.org) and the “generally recognized as safe” (GRAS) status conferred by the Flavor and Extracts Manufacturers Association (http://www.femaflavor.org). However, these limits and guidelines are not always applicable or relevant to the way that essential oils are employed in aromatherapy, and thus further safety advice for this discipline is of utmost importance.
Given the main routes of administration of essential oils, the predominant potential hazards are dermatitic reactions (allergic, irritant, and photocontact) and mucous membrane irritation. The risk of toxicity is very low unless the essential oil is consumed or used in inappropriate concentrations on the skin.
There have been very few documented cases of client harm as a result of essential oil use when the oils are administered or recommended by aromatherapists. However, reporting of adverse effects is not well coordinated. Some aromatherapy member associations are considering implementing a yellow card vigilance scheme such as the Adverse Reactions to Aromatherapy (ARIA) system recently adopted by the International Federation of Professional Aromatherapists (http://www.ifparoma.org) for its members, whereby practitioners and patients can report adverse reactions should they arise (Kayne, 2006). Thus far, reporting has been extremely low.
Accidental or deliberate misuse of essential oils in the home environment is more widely reported and often involves children, who are generally more vulnerable to adverse effects (Beccara, 1995; Darben et al, 1998; Tibballs, 1995). Consistent abuse of airborne aromatics in the home environment can also lead to airborne contact dermatitis (Schaller et al, 1995) as well as skin allergy (Weiss et al, 1997). Occupational exposure can also lead to contact dermatitis reactions (Ackerman et al, 2009; Wakelin et al, 1998).
Anecdotal negative reporting regarding the use of professional aromatherapy in clinical environments includes instances in which clients or care staff find some aromas too harsh or strong, provoking headaches, malaise, nausea, or coughing, although such cases are extremely rare.
Because it is exceptionally difficult to control for adverse incidents in the use of essential oils by the general public, who have easy access to these potent substances without the necessary safety information, support, and guidance, the role of the aromatherapist as educator is of paramount importance.
Considering the increased exposure that aromatherapists have to essential oils and related products, in terms of both dose and frequency of exposure, it is not surprising that there is more reporting of risk to the therapist than of risk to the client, especially with regard to skin reactions such as allergic contact dermatitis, although these, too, remain sparsely documented. There are a number of case reports of aromatherapists (usually those who have been in practice for a number of years) becoming sensitized or allergic to the products that they consistently use over time (Bleasel et al, 2002; Selvaag et al, 1995). Because many of these products have similar chemical composition, once sensitization is established the therapist often reacts to not just one but several essential oils, which in some cases necessitates a change in career.
It has been known for a number of years that the presence of oxidized essential oil components increases the risk of contact allergy and skin irritation (Chang et al, 1997; Christensson et al, 2008, 2009; Wakelin et al, 1998). These include the oxidation products of very common and unstable components such as d-limonene and linalool. This fact makes the issue of quality control of utmost importance to the aromatherapist in terms of sourcing and storage of essential oils. An additional challenge for the therapist is to obtain fresh and high-quality essential oils that are fully identified with regard to their species, plant part origin, and precise chemical composition.
Few documented drug–essential oil interactions have been reported in the literature, and most pertain to the internal consumption of essential oils rather than exposure via dermal application or inhalation. This situation is in contrast to the well-documented drug-herb interactions such as those involving Hypericum perforatum, Panax ginseng, Gingko biloba, and other herbs. As a result of lack of reporting, much of the information on risk of interactions between drugs and essential oils is speculative, with most research evidence coming from animal studies rather than actual reporting of interactions in humans.
Most potential for interaction lies in the fact that many essential oil components have been found to be inducers or inhibitors of enzyme systems such as members of the cytochrome P-450 family and glutathione S-transferase (Ganzera et al, 2006; Jori et al, 1969; Lam et al, 1991; Parke et al, 1974). However, because of pharmacokinetic differences as well as the relatively low concentrations of doses of essential oils when they are inhaled or topically applied, the likelihood of drug–essential oil interaction is greatly reduced if traditional holistic aromatherapy interventions are used (unless the drug is also administered topically or inhaled).
When essential oils are taken orally on a regular basis, however, given their concentrated nature, the risk of interaction is possibly equal to or greater than that with ingested herbal medicines. The fact that as yet there is little reporting of this risk may relate to the relatively recent upsurge in interest and use of ingestion as a means of administering essential oils. The aromatherapy profession needs to remain vigilant in this regard, because in some countries, ingestion of essential oils by the general public without support or professional supervision is increasingly promoted by companies, and the assumption is that natural products are without risk and are safe alternatives to medical care.
Even when essential oils are administered via inhalation, the therapist needs to be aware of possible conflicts, such as between essential oils that contain 1,8-cineole (e.g., niaouli, eucalyptus) and certain drugs like barbiturates (Jori et al, 1970). This component has been shown to induce enzyme systems and thus drug detoxification.
As with all potential drug interactions, the risk is raised when the patient is prescribed drugs that have a low therapeutic index, such as warfarin, barbiturates, and digoxin. With these medications, any small shift in serum levels can have profound consequences, and thus typically aromatherapists use lower doses of oils and work only with topical and inhaled formulations for patients taking these medications. They also need to be aware of the increased risk associated with certain essential oils containing potent components such as methyl salicylate (e.g., wintergreen) and eugenol (e.g., cloves), even when applied externally, because of the higher risk of bleeding if the patient is taking anticoagulant therapy or has a clotting disorder (Joss et al, 2000; Srivastava et al, 1990).
When essential oils are administered via the skin, the therapist needs to beware of potential conflict with topical drug preparations such as corticosteroids and transdermal drug delivery systems such as nicotine patches, hormone patches, and nausea medication patches.
As can be seen, the risk of harm from essential oils when used appropriately is extremely low. Certain individuals may be more at risk than others from essential oil hazards; these groups are listed in Box 23-3. Although aromatherapy is not contraindicated for these individuals, it is common for the aromatherapist to use extra caution with essential oil selection, dose, and route of administration to minimize risk.
BOX 23-3 Individuals Most at Risk for Essential Oil Hazard
As can be seen, with the increase in research and publication of studies in professional journals that demonstrate the therapeutic benefits of essential oils in clinical settings, the future looks bright for continued integration into a range of medical settings, especially as training standards improve and specialist courses are developed for certain areas such as elder care, psychiatry, oncology, palliative care, and midwifery.
A significant, as yet relatively unimplemented aspect of essential oil therapeutics is the role of essential oils in the realm of infection control (prevention and treatment). There is ever-increasing evidence that essential oils can exert significant antimicrobial effects via both direct contact (Jirovetz et al, 2007; Sherry et al, 2003) and airborne contact (Inouye, 2003; Inoue et al, 2001, 2003; Krist et al, 2006; Pibiri et al, 2006, Sato et al, 2007) and that they may offer antimicrobial solutions for multidrug-resistant organisms such as methicillin-resistant Staphylococcus aureus (Caelli et al, 2000; Dryden et al, 2004; Opalchenova et al, 2003). The natural presence of essential oils protects their host plants from microbial predation, and these oils may exert these same influences in clinical settings. This activity raises real possibilities for essential oils to offer direct solutions in clinical environments that typically have a high microbial load, in which patients are more likely to be prone to nosocomial infections that are resistant to antibiotic or antifungal therapy.
With the increasing acceptance and efficacy of aromatherapy in the clinical setting, this discipline is also increasingly subject to scrutiny to ensure safety and cost effectiveness. Although ultimately these measures are beneficial in the long term, we may well see a reduction in aromatherapy service provision in the current health care climate until its efficacy, cost effectiveness, and safety can be further demonstrated. In a cost-driven society with the financial constraints that exist in medical settings, where departments of finance hold the purse strings and choose essential oil suppliers by cost alone, the result can be the sourcing of cheaper essential oils of poorer quality for therapy. This practice can ultimately be detrimental in terms of both reduced efficacy and increased risk to the client.
In addition, with the increase in the risk of litigation, certain constraints are put on the therapy that also can limit its potential use. One example is the use of airborne diffusion for effective disinfection in clinical environments. Despite clear evidence demonstrating the potential of these active agents to provide airborne disinfection, significantly reducing microbial load, including that of multiresistant strains, the diffusion of essential oils in public areas such as waiting rooms or hospital wards is not widely practiced for fear of complaint or adverse reactions that may result in legal claims.
One other limiting factor is the perceived rise in multiple chemical sensitivity syndrome and the development of “fragrance-free” environments. Because essential oils are viewed more as fragrances than as therapeutically active substances with potential benefit, their use in some hospitals has been withdrawn.
What is also needed is a clearer distinction between the main aromatherapy practice styles and greater public awareness of these styles. Currently public opinion of aromatherapy remains quite general, with little expectation as to its benefits other than providing a “feel good” therapy. Although the psychological benefits of aromatherapy can be readily appreciated through the well-being aspect of this pleasurable therapy, essential oils also offer demonstrated benefit in many other ways.
Chapter References can be found on the Evolve website at http://evolve.elsevier.com/Micozzi/complementary/