A
generalised lymphadenopathy, 29–31
hints for,24
multiple abdominal scars,33–35
renal replacement therapy,39–42
Abducens nerve palsy,84
Abnormal blood, patient with, 48–50
Acoustic neuroma, 167
Adenocarcinoma, 15
ADPKD, see Autosomal dominant polycystic kidney disease (ADPKD)
Alport’ s syndrome (AS), 41
Amyotrophic lateral sclerosis, 94
Anaesthesia, 82
Ankylosing spondylitis, 158–160
Anti-CCP, see Anticyclic citrullinated peptide (Anti-CCP) antibodies
Anticipation, 82
Anticoagulants, 80
Anticyclic citrullinated peptide (Anti-CCP) anti-bodies, 183
Aortic regurgitation (AR), 105–107
Aortic valve replacement (AVR), 103
AR, see Aortic regurgitation (AR)
AS, see Alport’ s syndrome (AS); Aortic stenosis (AS) Ascites, 28
Austin Flint murmur, 107
Autoimmune disease human leucocyte antigen associations, 72
Autonomic neuropathy, 89
Autosomal dominant polycystic kidney disease (ADPKD), 37
AVR, see Aortic valve replacement (AVR)
B
Back pain, patient with, 51–53
causes of, in elderly patient, 52
red-flag signs, 52
symptoms, 52
tumours, 53
Bilateral LMN cranial nerve VII palsy, 166–167
Bilateral lower-zone crackles, 4
Bitemporal hemianopia, 100
B-symptoms, 30
C
Cancers, 67
Eisenmenger’ s syndrome, 107–109
hints for, 102
hypertrophic cardiomyopathy, 110–112
mitral valve prolapse, 117–118
mixed aortic valve disease, 119–120
mixed mitral valve disease, 120–122
prosthetic heart valves, 122–124
tricuspid regurgitation, 124–126
ventricular septal defect, 127–129
Carpal tunnel syndrome, 90, 182–184
CHADSVASC, 163
Charcot- Marie- Tooth disease, 89
Cholestasis, 62
Chronic lymphocytic leukaemia (CLL), 30
Chronic myeloid leukaemia (CML), 32
Chronic obstructive pulmonary disease (COPD), 4–7
Chronic primary MR, 116
CLL, see Chronic lymphocytic leukaemia (CLL)
CML, see Chronic myeloid leukaemia (CML)
Coeliac disease
conditions associated with, 59
diagnosis and management of, 60
differential diagnosis of, 55
features of uncomplicated vasovagal syncope, 55
Community-acquired pneumonia, 8
Complex ophthalmoplegia, 84
COPD, see Chronic obstructive pulmonary disease (COPD)
Cor pulmonale, 6
management of gastro-oesophageal reflux disease, 58
red-flag symptoms, 57
upper GI endoscopy, 57
CREST syndrome, see Limited systemic sclerosis (SSc)
D
Deteriorating patient, care in, 135–137
Diabetes Mellitus, 72
Diabetic maculopathy, 164
Diarrhoea, patient with, 58–60
Diffuse systemic sclerosis, 185
Dopamine agonists, 87
Driver and Vehicle Licensing Agency (DVLA), 67, 138, 139
DVLA, see Driver and Vehicle Licensing Agency (DVLA)
E
Eisenmenger’ s syndrome, 107–109
Electromyography (EMG), 82
Empyema, 8
Endocarditis, 126
Ethics, and communication skills, 131–154
care in deteriorating patient, 135–137
hints for, 132
initiating new therapy, 140–142
organ transplantation, 152–154
Exudative effusion, 19
F
Foot drop, 91
Friedreich’ s ataxia, 78
G
Gastrointestinal (GI) endoscopy, 57
Gastro-oesophageal reflux disease, 58
Generalised lymphadenopathy, 29–31
GI, see Gastrointestinal (GI) endoscopy
Goitre, 173
Graves’ disease, 173
H
HASBLED, 163
HCM, see Hypertrophic cardiomyopathy (HCM)
Hepatic encephalopathy, 27
Hereditary haemorrhagic telangiectasia, 25
Hereditary spastic paraparesis, 98
abnormal blood, patient with, 48–50
back pain, patient with, 51–53
diarrhoea, patient with, 58–60
hints for, 48
joint pains, patient with, 63–65
left arm weakness, patient with, 65–67
visual disturbance, patient with, 67–70
weight loss, patient with, 70–72
Hodgkin’ s lymphoma, 30
Homonymous hemianopia, 99
Hypercalcaemia, 50
Hyperthyroid emergencies, 173
Hypertrophic cardiomyopathy (HCM), 110- 112
I
IBD, see Inflammatory bowel disease (IBD)
Idiopathic intracranial hypertension (IIH), 170–171
Inflammatory bowel disease (IBD), 34
Internuclear ophthalmoplegia, 84
J
Joint pains, patient with, 63–65
L
Lateral medullary syndrome, 80
Left arm weakness, patient with, 65–67
Lhermitte’ s sign, 96
Limited systemic sclerosis (SSc), 185
Liver transplantation, 28
LMN, see Lower motor neurone (LMN) lesion
Lobectomy, 20
Localised scleroderma, 185
Long-term oxygen therapy (LTOT), 6
Lower motor neurone (LMN) lesion, 166
LTOT, see Long-term oxygen therapy (LTOT)
Lung transplantation, 21
M
Malabsorption, 60
Mitral regurgitation (MR), 114–117
Mitral valve prolapse (MVP), 117–118
Mixed aortic valve disease, 119–120
Mixed mitral valve disease, 120–122
MND, see Motor neurone disease (MND)
Mononeuritis multiplex, 92
Motor neurone disease (MND), 92–95
MR, see Mitral regurgitation (MR)
Multiple abdominal scars, 33–35
MVP, see Mitral valve prolapse (MVP)
Myeloproliferative disorders, 32
N
National Institute for Health and Care Excellence (NICE), 6, 162
Nephrectomy, 38
hints for, 76
NICE, see National Institute for Health and Care Excellence (NICE)
NOACs, see Novel oral anticoagulants (NOACs)
Non-Hodgkin’ s lymphoma, 30
Nonproliferative diabetic retinopathy, 164
Non-small-cell lung cancer (NSCLC), 15
Novel oral anticoagulants (NOACs), 162
NSCLC, see Non-small-cell lung cancer (NSCLC)
O
Optic atrophy, 171
Optic nerve lesion, 100
Organ transplantation, 152–154
P
PACES, see Practical Assessment of Clinical Examination Skills (PACES)
Pancoast’ s syndrome, 15
Papilloedema, 170
Paraneoplastic syndromes, 15
Parapneumonic effusion, 8
Peroneal nerve palsy, 91
Peutz- Jeghers syndrome, 25
Pneumonectomy, 20
Pneumonia, 8
Polycystic kidney disease, 37
Polycythaemia rubra vera (PRV), 44
Polymyalgia rheumatica, 70
Practical Assessment of Clinical Examination Skills (PACES), xxiii, xxv-xxvii, 189
Primary biliary cirrhosis (PBC)
autoimmune associations of, 62
control of disease, 62
investigation of suspected, 62
management of itch in cholestasis, 62
Primary hyperparathyroidism, 50
Primary lateral sclerosis, 93
Primary MR, 116
Progressive bulbar palsy, 94
Progressive muscular atrophy, 94
Proliferative diabetic retinopathy, 164
Prosthetic heart valves, 122–124
PRV, see Polycythaemia rubra vera (PRV)
Psoriatic arthritis, 181
R
Radial nerve palsy, 91
Renal cystic disorders, 38
Renal replacement therapy, 39–42
chronic obstructive pulmonary disease (COPD), 4–7
hints for, 2
patient with previous lung surgery, 20–21
Rheumatoid arthritis, 13
with carpal tunnel syndrome, 182–184
diagnostic criteria for, 64
pharmacological management of, 65
S
Sarcoidosis, 50
SCD, see Sudden cardiac death (SCD)
SCLC, see Small-cell lung cancer (SCLC)
Scleroderma, 185
Secondary MR, 116
Small-cell lung cancer (SCLC), 15
Space-occupying lesions, 67
Spinal cord compression, 98
Spleen, 43
Splenectomy, 43
Squamous cell carcinoma, 15
SSc, see Limited systemic sclerosis (SSc)
Structural valve deterioration (SVD), 123
Sudden cardiac death (SCD), 111
Superior vena caval obstruction (SVCO), 16
SVD, see Structural valve deterioration (SVD)
T
Tabes dorsalis, 90
TAVI, see Transcatheter aortic valve implantation (TAVI)
TB, see Old tuberculosis (TB)
Thoracoscopy, 19
Thyroid cancer, 174
Thyroid mass, 175
Transcatheter aortic valve implantation (TAVI), 103–104
Transudative effusion, 19
Transverse myelitis, 98
Tricuspid regurgitation, 124–126
U
UC, see Ulcerative colitis (UC)
Uhthoff’ s phenomenon, 96
UIP, see Usual interstitial pneumonia (UIP) pattern
Ulcerative colitis (UC), 34
Ulnar nerve palsy, 90
UMN, see Upper motor neurone (UMN) lesion
Unilateral CN VII palsy, 166
Upper motor neurone (UMN) lesion, 166
Usual interstitial pneumonia (UIP) pattern, 13
V
Vasovagal syncope, 55
Ventricular septal defect (VSD), 127–129
Visual disturbance, patient with, 67–70
Von Hippel- Lindau syndrome, 38
VSD, see Ventricular septal defect (VSD)
W
Wallenberg’ s syndrome, see Lateral medullary syndrome
Warfarin, 80
Weight loss, patient with, 70–72
World Health Organization (WHO), 72