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Index
Cover
Frontmatter
1. General Aspects of Aging
Protein Redox-Regulation Mechanisms in Aging
Nitrosative Stress in Aging – Its Importance and Biological Implications in NF-κB Signaling
Intervention with Multiple Micronutrients Including Dietary and Endogenous Antioxidants for Healthy Aging
Advanced Glycation End Products, RAGE, and Aging
Sirtuins and Mammalian Aging
Estrogenic Modulation of Longevity by Induction of Antioxidant Enzymes
Mitochondrial Respiratory Function Decline in Aging and Life-Span Extension by Caloric Restriction
Methylglyoxal, Oxidative Stress, and Aging
2. The Cardiovascular System
Novel Strategies for Neurovascular Longevity During Aging
Oxidative Stress in Vascular Disease
The Role of Mitochondrial Reactive Oxygen Species Formation for Age-Induced Vascular Dysfunction
Aging, Oxidative Stress, and Cardiovascular Disorders
Oxidative Stress, Aging, and Cardiovascular Disease
Antioxidation in Prevention of Cardiovascular Diseases – An Effect of Polyphenols
Vascular Aging and Oxidative Stress: Hormesis and Adaptive Cellular Pathways
Role of Oxidative Stress in Mediating Elevated Blood Pressure with Aging
3. The Nervous System
Melatonin, Oxidative Stress, and the Aging Brain
The SAM Strain of Mice, a Higher Oxidative Stress, Age-Dependent Degenerative Disease, and Senescence Acceleration Model
Antioxidants Combined with Behavioral Enrichment Can Slow Brain Aging
Role of Nitric Oxide in Neurodegeneration and Vulnerability of Neuronal Cells to Nitric Oxide Metabolites and Reactive Oxygen Species
Free Radical–Mediated Damage to Brain in Alzheimer’s Disease: Role of Acrolein and Preclinical Promise of Antioxidant Polyphenols
An Epigenetic Model for Susceptibility to Oxidative DNA Damage in the Aging Brain and Alzheimer’s Disease
Backmatter
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