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Index
Cover image Title Page Dedication Copyright Contents of EBM Toolbox Index of Teaching Moments Preface
Acknowledgements
Introduction
What is evidence-based medicine? Why the need for a new edition of this book? How do we practise EBM? Can clinicians practise EBM? What's the “E” in EBM? - - What are the limitations of EBM? How is this resource organized? References
1 Asking answerable clinical questions
Background and foreground questions Our reactions to knowing and to not knowing Where and how clinical questions arise Practising evidence-based medicine in real time Why bother formulating questions clearly? Teaching questions for EBM in real time References
2 Acquiring the evidence
Orientation to evidence-based information resources: where to find the best evidence How to deal with the evidence that finds US (“push” evidence): keeping up to date efficiently Walking the walk: searching for evidence to solve patient problems References
3 Appraising the evidence
Further reading
4 Therapy
Further reading about individual randomized trials Further reading about systematic reviews Further reading about individual randomized trials and qualitative studies Further reading about clinical decision analysis Further reading about economic analysis Further reading about n-of-1 trials References
5 Diagnosis and screening
What is normal or abnormal? Is this evidence about the accuracy of a diagnostic test valid? Does this (valid) evidence demonstrate an important ability of this test to accurately distinguish patients who do and don't have a specific disorder? Sensitivity, specificity, and likelihood ratios Practising evidence-based medicine in real time Screening and case finding—proceed with caution! References Further reading
6 Prognosis
Types of reports on prognosis Are the results of this prognosis study valid? Is this valid evidence about prognosis important? (Box 6.2) Can we apply this valid, important evidence about prognosis to our patient? (Box 6.3) Practising evidence-based medicine in real time References Further reading
7 Harm
Types of reports on harm/etiology References Further reading
8 Evaluation
How am I doing? Is our practice improving? How much of our practice is evidence based? Evaluating our performance as teachers References Further reading
9 Teaching evidence-based medicine
Three modes of teaching EBM Teaching EBM—top 10 successes Teaching EBM—top 10 failures Teaching and learning EBM on an inpatient service Teaching and learning EBM in the outpatient clinic Writing structured summaries of evidence-based learning episodes Incorporating EBM into existing educational sessions Integrating EBM into a curriculum Integrating EBM into 4-year medical school curriculum—a worked example , , Learning more about how to teach EBM Tips for teaching EBM in clinical teams and other small groups References
Appendix 1 Glossary
Terms you are likely to encounter in your clinical reading Terms specific to treatment effects How to calculate likelihood ratios (LRs) Sample calculation Calculation of odds ratio/relative risk
Appendix 2 Confidence intervals
Statistical inference Calculating confidence intervals Multiple estimates of treatment effect Confidence intervals in meta-analysis Clinical significance section Comment References
Index
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