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Index
Preface
Acknowledgments
CHAPTER 1 Exercise Testing and Interpretation
CHAPTER 2 Physiology of Exercise
CHAPTER 3 Changes in Blood Gases and pH during Exercise
CHAPTER 4 Measurements during Integrative Cardiopulmonary Exercise Testing
CHAPTER 5 Pathophysiology of Disorders Limiting Exercise
CHAPTER 6 Clinical Exercise Testing
CHAPTER 7 Normal Values
CHAPTER 8 Diagnostic Specificity of Exercise Intolerance: A Flowchart Approach
CHAPTER 9 Clinical Applications of Cardiopulmonary Exercise Testing
CHAPTER 10 Case Presentations
Case 1. Normal Man
Case 2. Normal Athletic Man
Case 3. Normal Woman: Air and Oxygen Breathing Studies
Case 4. Normal Man
Case 5. Exceptionally Fit Man with Mild Lung Disease
Case 6. Normal Subject: Cycle and Treadmill Studies
Case 7. Normal Subject: Before and After β-Adrenergic Blockade
Case 8. Normal Subject: Immediate Effects of Cigarette Smoking
Case 9. Active Normal Man with Suspected Cardiac Disease
Case 10. Normal Sedentary Woman
Case 11. Normal Aging Athletic Man
Case 12. Chronic Heart Failure: Nonischemic Cardiomyopathy
Case 13. Chronic Heart Failure: Before and after Therapy
Case 14. Chronic Heart Failure: Oscillatory Ventilation and Gas Exchange
Case 15. Chronic Heart Failure: Cardiomyopathy with Intraventricular Conduction Delay
Case 16. Myocardial Ischemia: Undiagnosed Angina and Hypertension
Case 17. Myocardial Ischemia: Atypical Chest Pain
Case 18. Myocardial Ischemia: Small Vessel Disease
Case 19. Myocardial Ischemia: Interim Development of Coronary Artery Disease over 3 Years
Case 20. Myocardial Ischemia: Coronary Artery Disease in a Previously Athletic Man
Case 21. Peripheral Arterial Disease
Case 22. Cardiovascular Impairment with Hypertension and Carboxyhemoglobinemia
Case 23. Rate Disturbance due to β-Adrenergic Blockade for Treatment of Systemic Hypertension
Case 24. Atrial Fibrillation with Rapid Ventricular Response during Exercise
Case 25. Chronotropic Insufficiency with Escape Rhythm
Case 26. Hypertrophic Cardiomyopathy with Postexercise Vasodepressor Syncope
Case 27. Mitral Insufficiency
Case 28. Congenital Heart Disease Surgically Corrected in Infancy
Case 29. Congenital Heart Disease: Surgically Corrected Transposition of the Great Arteries
Case 30. Patent Ductus Arteriosus with Left-to-Right Shunt
Case 31. Patent Ductus Arteriosus with Right-to-Left Shunt (Eisenmenger Ductus)
Case 32. Eisenmenger Complex (Ventricular Septal Defect with Pulmonary Hypertension)
Case 33. Early Onset of Exercise Lactic Acidosis: Differentiating Circulatory from Muscular Impairment
Case 34. Early Onset of Exercise Lactic Acidosis Suggesting Circulatory Impairment
Case 35. Pulmonary Hypertension with Patent Foramen Ovale
Case 36. Idiopathic Pulmonary Hypertension before and after Treatment
Case 37. Long-standing Idiopathic Pulmonary Hypertension: Serial Tests over 17 Years of Treatment
Case 38. Idiopathic Pulmonary Hypertension
Case 39. Mixed Connective Tissue Disease with Pulmonary Involvement
Case 40. Pulmonary and Systemic Vasculitis: Air and Oxygen Breathing Studies
Case 41. Scleroderma with Pulmonary and Pulmonary Vascular Involvement
Case 42. Severe Pulmonary Vascular Disease Secondary to Sarcoidosis: Air and Oxygen Breathing Studies
Case 43. Exercise-Induced Pulmonary Hypertension Secondary to Left Ventricular Diastolic Dysfunction
Case 44. Intrapulmonary Right-to-Left Shunt due to Pulmonary Arteriovenous Fistulae
Case 45. Mild Chronic Bronchitis with Normal Exercise Performance
Case 46. Emphysema with Mild Airway Obstruction
Case 47. Severe Emphysema
Case 48. Emphysema with Pulmonary Vascular Disease
Case 49. Severe Emphysema and Bronchitis: Air and Oxygen Breathing Studies
Case 50. Bullous Emphysema: Before and after Bullectomy
Case 51. Chronic Obstructive Lung Disease with a History of Heart Failure
Case 52. Mild Obstructive Airway Disease with Disproportionate Exertional Dyspnea
Case 53. Mild Pulmonary Asbestosis
Case 54. Severe Pulmonary Asbestosis
Case 55. Idiopathic Interstitial Lung Disease
Case 56. Interstitial Lung Disease
Case 57. Sarcoidosis
Case 58. Interstitial Pneumonitis: Before and after Corticosteroid Therapy
Case 59. Interstitial Pulmonary Fibrosis: Air and Oxygen Breathing Studies
Case 60. Obesity Contributing to Ventilatory Limitation
Case 61. Extrapulmonary Restriction: Ankylosing Spondylitis
Case 62. Extrapulmonary Restriction: Scoliosis
Case 63. McArdle Disease
Case 64. Myopathy with Exertional Rhabdomyolysis
Case 65. Congenital Mitochondrial Myopathy
Case 66. Mitochondrial Myopathy
Case 67. Mixed Disorder: Chronic Bronchitis and Obesity
Case 68. Mixed Disorder: Peripheral Arterial Disease, Anemia, Carboxyhemoglobinemia, and Cardiac Dysfunction
Case 69. Mixed Disorder: Mild Interstitial Lung Disease, Obstructive Airway Disease, and Myocardial Ischemia
Case 70. Mild Interstitial Lung Disease, Silent Myocardial Ischemia, and Uncontrolled Systemic Hypertension
Case 71. Mixed Disease: Aortic Stenosis, Mitral Stenosis, and Obstructive Airway Disease
Case 72. Mixed Disorder: Obstructive Airway Disease, Talc Pneumoconiosis, and Pulmonary Vascular Disease
Case 73. Mixed Disorder: Peripheral Arterial Disease and Obstructive Lung Disease
Case 74. Exercise Testing for Staging and Prognosis in Chronic Heart Failure
Case 75. Exercise Testing in Preoperative Evaluation for Lung Cancer Resection
Case 76. Exercise Testing for Evaluation of Work Fitness: Extreme Obesity
Case 77. Exercise Testing for Assessment before and after Pulmonary Rehabilitation for Chronic Obstructive Pulmonary Disease
Case 78. Evaluation of Unexplained Dyspnea: A Morbidly Obese Asthmatic
Case 79. Evaluation of Unexplained Dyspnea: Thromboembolic Pulmonary Vascular Disease
Case 80. Evaluation of Unexplained Dyspnea: An Obese Woman at Risk for Pulmonary Hypertension
Appendix A. Symbols and Abbreviations
Appendix B. Glossary
Appendix C. Calculations, Formulas, and Examples
Appendix D. Placement of a Brachial Artery Catheter
Appendix E. Tables and Nomogram
Index
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