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Index
Cover Title Page Copyright A Note from the Publisher Authors Contents PART 1.4 – UNDERSTANDING THE VALUE OF MOLECULAR CELL BIOLOGY AND GENE ANALYSIS FOR THE NEXT GENERATION OF COSMETIC PRODUCTS
1.4.1 Introduction 1.4.2 Principles of Molecular Biology 1.4.3 Proteomics, genomics and epigenetics 1.4.4 Application for Skin Care 1.4.5 (Future perspectives) Conclusion References Glossary
PART_4.3.3 MICRORNAS IN SKIN PHYSIOLOGY
4.3.3.1 RNA interference and microRNAs—timeline of the discoveries
a. Discovery of microRNAs b. The concept of RNA interference
4.3.3.2 MicroRNAs - nomenclature, structure, function, mechanism of action 4.3.3.3 MicroRNAs regulate various aspects of human physiology and epigenetics 4.3.3.4 MicroRNAs and skin physiology
a. Introduction on skin b. MicroRNAs and cutaneous biology c. Epidermal renewal and skin barrier d. MiR-203 is a master regulator of epidermal differentiation e. P63, SOCS3, Zfp281, JUN, and ABL1 are the major mir-203 targets in the epidermis f. Other microRNAs important in epidermal renewal g. Skin pigmentation h. Dermal physiology i. MicroRNAs and the hypodermal adipocytes j. Hair follicle morphogenesis
4.3.3.5 Interest of microRNAs in the evaluation in vitro of anti-aging dermo-cosmetic ingredients
a. Skin aging b. MicroRNAs and cellular senescence c. Tissue-engineering and microRNA studies
Conclusion References Glossary
PART_5.6 – EPIGENETICS OF SKIN AGING
5.6.1  The Human Genome Project Gives Birth To The Epigenetic ­Revolution 5.6.2  Epigenetics Defined 5.6.3  Two Primary Epigenetic Mechanisms
1.  DNA methylation 2.  Chromatin remodeling and histone modification
5.6.4  Epigenetic Links To Aging 5.6.5  Epigenetics And Aging Skin 5.6.6  Epigenetics Mechanisms In DNA Damage and Repair 5.6.7  Cosmetic Ingredients As Epigenetic Modifiers 5.6.8  Nutriepigenetics: How Diet Alters the Epigenome 5.6.9  Epigenetics: The Unifying Theory Of Aging? 5.6.10  What the Future Holds References Glossary List of Figures
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