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Index
Preface
1 Biochemistry & Medicine Robert K. Murray, MD, PhD 2 Water & pH Peter J. Kennelly, PhD & Victor W. Rodwell, PhD
SECTION I Structures & Functions of Proteins & Enzymes
3 Amino Acids & Peptides Peter J. Kennelly, PhD & Victor W. Rodwell, PhD 4 Proteins: Determination of Primary Structure Peter J. Kennelly, PhD & Victor W. Rodwell, PhD 5 Proteins: Higher Orders of Structure Peter J. Kennelly, PhD & Victor W. Rodwell, PhD 6 Proteins: Myoglobin & Hemoglobin Peter J. Kennelly, PhD & Victor W. Rodwell, PhD 7 Enzymes: Mechanism of Action Peter J. Kennelly, PhD & Victor W. Rodwell, PhD 8 Enzymes: Kinetics Peter J. Kennelly, PhD & Victor W. Rodwell, PhD 9 Enzymes: Regulation of Activities Peter J. Kennelly, PhD & Victor W. Rodwell, PhD Peter J. Kennelly, PhD & Victor W. Rodwell, PhD
10 Bioinformatics & Computational Biology
SECTION II Bioenergetics & the Metabolism of Carbohydrates & Lipids
Kathleen M. Botham, PhD, DSc & Peter A. Mayes, PhD, DSc Kathleen M. Botham, PhD, DSc & Peter A. Mayes, PhD, DSc Kathleen M. Botham, PhD, DSc & Peter A. Mayes, PhD, DSc David A. Bender, PhD & Peter A. Mayes, PhD, DSc Kathleen M. Botham, PhD, DSc & Peter A. Mayes, PhD, DSc David A. Bender, PhD & Peter A. Mayes, PhD, DSc David A. Bender, PhD & Peter A. Mayes, PhD, DSc David A. Bender, PhD & Peter A. Mayes, PhD, DSc David A. Bender, PhD & Peter A. Mayes, PhD, DSc David A. Bender, PhD & Peter A. Mayes, PhD, DSc David A. Bender, PhD & Peter A. Mayes, PhD, DSc Kathleen M. Botham, PhD, DSc & Peter A. Mayes, PhD, DSc Kathleen M. Botham, PhD, DSc & Peter A. Mayes, PhD, DSc Kathleen M. Botham, PhD, DSc & Peter A. Mayes, PhD, DSc Kathleen M. Botham, PhD, DSc & Peter A. Mayes, PhD, DSc Kathleen M. Botham, PhD, DSc & Peter A. Mayes, PhD, DSc
11 Bioenergetics: The Role of ATP 12 Biologic Oxidation 13 The Respiratory Chain & Oxidative Phosphorylation 14 Carbohydrates of Physiologic Significance 15 Lipids of Physiologic Significance 16 Overview of Metabolism & the Provision of Metabolic Fuels 17 The Citric Acid Cycle: The Catabolism of Acetyl-CoA 18 Glycolysis & the Oxidation of Pyruvate 19 Metabolism of Glycogen 20 Gluconeogenesis & the Control of Blood Glucose 21 The Pentose Phosphate Pathway & Other Pathways of Hexose Metabolism 22 Oxidation of Fatty Acids: Ketogenesis 23 Biosynthesis of Fatty Acids & Eicosanoids 24 Metabolism of Acylglycerols & Sphingolipids 25 Lipid Transport & Storage 26 Cholesterol Synthesis, Transport, & Excretion
SECTION III Metabolism of Proteins & Amino Acids
Victor W. Rodwell, PhD Victor W. Rodwell, PhD Victor W. Rodwell, PhD Victor W. Rodwell, PhD Robert K. Murray, MD, PhD
27 Biosynthesis of the Nutritionally Nonessential Amino Acids 28 Catabolism of Proteins & of Amino Acid Nitrogen 29 Catabolism of the Carbon Skeletons of Amino Acids 30 Conversion of Amino Acids to Specialized Products 31 Porphyrins & Bile Pigments
SECTION IV Structure, Function, & Replication of Informational Macromolecules
Victor W. Rodwell, PhD Victor W. Rodwell, PhD P. Anthony Weil, PhD P. Anthony Weil, PhD P. Anthony Weil, PhD P. Anthony Weil, PhD P. Anthony Weil, PhD P. Anthony Weil, PhD
32 Nucleotides 33 Metabolism of Purine & Pyrimidine Nucleotides 34 Nucleic Acid Structure & Function 35 DNA Organization, Replication, & Repair 36 RNA Synthesis, Processing, & Modification 37 Protein Synthesis & the Genetic Code 38 Regulation of Gene Expression 39 Molecular Genetics, Recombinant DNA, & Genomic Technology
SECTION V Biochemistry of Extracellular & Intracellular Communication
Robert K. Murray, MD, PhD & Daryl K. Granner, MD P. Anthony Weil, PhD P. Anthony Weil, PhD
40 Membranes: Structure & Function 41 The Diversity of the Endocrine System 42 Hormone Action & Signal Transduction
SECTION VI Special Topics
David A. Bender, PhD & Peter A. Mayes, PhD, DSc David A. Bender, PhD David A. Bender, PhD Robert K. Murray, MD, PhD Robert K. Murray, MD, PhD Robert K. Murray, MD, PhD & Frederick W. Keeley, PhD Robert K. Murray, MD, PhD Robert K. Murray, MD, PhD, Molly Jacob, MB BS, MD, PhD, & Joe Varghese, MB BS, MD Peter L. Gross, MD, MSc, FRCP(C), Robert K. Murray, MD, PhD, & Margaret L. Rand, PhD Robert K. Murray, MD, PhD Robert K. Murray, MD, PhD Peter J. Kennelly, PhD Robert K. Murray, MD, PhD, Molly Jacob, MB BS, MD, PhD, & Joe Varghese, MB BS, MD Joe Varghese, MB BS, MD, Molly Jacob, MB BS, MD, PhD, & Robert K. Murray, MD, PhD Robert K. Murray, MD, PhD & Peter L. Gross, MD, MSc, FRCP(C)
43 Nutrition, Digestion, & Absorption 44 Micronutrients: Vitamins & Minerals 45 Free Radicals and Antioxidant Nutrients 46 Intracellular Traffic & Sorting of Proteins 47 Glycoproteins 48 The Extracellular Matrix 49 Muscle & the Cytoskeleton 50 Plasma Proteins & Immunoglobulins 51 Hemostasis & Thrombosis 52 Red & White Blood Cells 53 Metabolism of Xenobiotics 54 The Biochemistry of Aging 55 Cancer: An Overview 56 Clinical Biochemistry 57 Biochemical Case Histories
Appendix The Answer Bank Index
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