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Index
Preface
1 Biochemistry & Medicine
Robert K. Murray, MD, PhD
2 Water & pH
Peter J. Kennelly, PhD & Victor W. Rodwell, PhD
SECTION I
Structures & Functions of Proteins & Enzymes
3 Amino Acids & Peptides
Peter J. Kennelly, PhD & Victor W. Rodwell, PhD
4 Proteins: Determination of Primary Structure
Peter J. Kennelly, PhD & Victor W. Rodwell, PhD
5 Proteins: Higher Orders of Structure
Peter J. Kennelly, PhD & Victor W. Rodwell, PhD
6 Proteins: Myoglobin & Hemoglobin
Peter J. Kennelly, PhD & Victor W. Rodwell, PhD
7 Enzymes: Mechanism of Action
Peter J. Kennelly, PhD & Victor W. Rodwell, PhD
8 Enzymes: Kinetics
Peter J. Kennelly, PhD & Victor W. Rodwell, PhD
9 Enzymes: Regulation of Activities
Peter J. Kennelly, PhD & Victor W. Rodwell, PhD
Peter J. Kennelly, PhD & Victor W. Rodwell, PhD
10 Bioinformatics & Computational Biology
SECTION II
Bioenergetics & the Metabolism of Carbohydrates & Lipids
Kathleen M. Botham, PhD, DSc & Peter A. Mayes, PhD, DSc
Kathleen M. Botham, PhD, DSc & Peter A. Mayes, PhD, DSc
Kathleen M. Botham, PhD, DSc & Peter A. Mayes, PhD, DSc
David A. Bender, PhD & Peter A. Mayes, PhD, DSc
Kathleen M. Botham, PhD, DSc & Peter A. Mayes, PhD, DSc
David A. Bender, PhD & Peter A. Mayes, PhD, DSc
David A. Bender, PhD & Peter A. Mayes, PhD, DSc
David A. Bender, PhD & Peter A. Mayes, PhD, DSc
David A. Bender, PhD & Peter A. Mayes, PhD, DSc
David A. Bender, PhD & Peter A. Mayes, PhD, DSc
David A. Bender, PhD & Peter A. Mayes, PhD, DSc
Kathleen M. Botham, PhD, DSc & Peter A. Mayes, PhD, DSc
Kathleen M. Botham, PhD, DSc & Peter A. Mayes, PhD, DSc
Kathleen M. Botham, PhD, DSc & Peter A. Mayes, PhD, DSc
Kathleen M. Botham, PhD, DSc & Peter A. Mayes, PhD, DSc
Kathleen M. Botham, PhD, DSc & Peter A. Mayes, PhD, DSc
11 Bioenergetics: The Role of ATP
12 Biologic Oxidation
13 The Respiratory Chain & Oxidative Phosphorylation
14 Carbohydrates of Physiologic Significance
15 Lipids of Physiologic Significance
16 Overview of Metabolism & the Provision of Metabolic Fuels
17 The Citric Acid Cycle: The Catabolism of Acetyl-CoA
18 Glycolysis & the Oxidation of Pyruvate
19 Metabolism of Glycogen
20 Gluconeogenesis & the Control of Blood Glucose
21 The Pentose Phosphate Pathway & Other Pathways of Hexose Metabolism
22 Oxidation of Fatty Acids: Ketogenesis
23 Biosynthesis of Fatty Acids & Eicosanoids
24 Metabolism of Acylglycerols & Sphingolipids
25 Lipid Transport & Storage
26 Cholesterol Synthesis, Transport, & Excretion
SECTION III
Metabolism of Proteins & Amino Acids
Victor W. Rodwell, PhD
Victor W. Rodwell, PhD
Victor W. Rodwell, PhD
Victor W. Rodwell, PhD
Robert K. Murray, MD, PhD
27 Biosynthesis of the Nutritionally Nonessential Amino Acids
28 Catabolism of Proteins & of Amino Acid Nitrogen
29 Catabolism of the Carbon Skeletons of Amino Acids
30 Conversion of Amino Acids to Specialized Products
31 Porphyrins & Bile Pigments
SECTION IV
Structure, Function, & Replication of Informational Macromolecules
Victor W. Rodwell, PhD
Victor W. Rodwell, PhD
P. Anthony Weil, PhD
P. Anthony Weil, PhD
P. Anthony Weil, PhD
P. Anthony Weil, PhD
P. Anthony Weil, PhD
P. Anthony Weil, PhD
32 Nucleotides
33 Metabolism of Purine & Pyrimidine Nucleotides
34 Nucleic Acid Structure & Function
35 DNA Organization, Replication, & Repair
36 RNA Synthesis, Processing, & Modification
37 Protein Synthesis & the Genetic Code
38 Regulation of Gene Expression
39 Molecular Genetics, Recombinant DNA, & Genomic Technology
SECTION V
Biochemistry of Extracellular & Intracellular Communication
Robert K. Murray, MD, PhD & Daryl K. Granner, MD
P. Anthony Weil, PhD
P. Anthony Weil, PhD
40 Membranes: Structure & Function
41 The Diversity of the Endocrine System
42 Hormone Action & Signal Transduction
SECTION VI
Special Topics
David A. Bender, PhD & Peter A. Mayes, PhD, DSc
David A. Bender, PhD
David A. Bender, PhD
Robert K. Murray, MD, PhD
Robert K. Murray, MD, PhD
Robert K. Murray, MD, PhD & Frederick W. Keeley, PhD
Robert K. Murray, MD, PhD
Robert K. Murray, MD, PhD, Molly Jacob, MB BS, MD, PhD, & Joe Varghese, MB BS, MD
Peter L. Gross, MD, MSc, FRCP(C), Robert K. Murray, MD, PhD, & Margaret L. Rand, PhD
Robert K. Murray, MD, PhD
Robert K. Murray, MD, PhD
Peter J. Kennelly, PhD
Robert K. Murray, MD, PhD, Molly Jacob, MB BS, MD, PhD, & Joe Varghese, MB BS, MD
Joe Varghese, MB BS, MD, Molly Jacob, MB BS, MD, PhD, & Robert K. Murray, MD, PhD
Robert K. Murray, MD, PhD & Peter L. Gross, MD, MSc, FRCP(C)
43 Nutrition, Digestion, & Absorption
44 Micronutrients: Vitamins & Minerals
45 Free Radicals and Antioxidant Nutrients
46 Intracellular Traffic & Sorting of Proteins
47 Glycoproteins
48 The Extracellular Matrix
49 Muscle & the Cytoskeleton
50 Plasma Proteins & Immunoglobulins
51 Hemostasis & Thrombosis
52 Red & White Blood Cells
53 Metabolism of Xenobiotics
54 The Biochemistry of Aging
55 Cancer: An Overview
56 Clinical Biochemistry
57 Biochemical Case Histories
Appendix
The Answer Bank
Index
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