Lippincott® Illustrated Reviews: Biochemistry, 8e by Emine Ercikan Abali, PhD -- Read -- Imperial Library of Trantor

Index

Cover Title Page Copyright Dedication Acknowledgments Contributing Editor, Online Unit Review Questions Reviewers Preface Contents Unit I: Protein Structure and Function

Chapter 1: Amino Acids and the Role of pH

I. Overview II. Structure III. Acidic and Basic Properties IV. Chapter Summary Study Questions

Chapter 2: Protein Structure

I. Overview II. Primary Structure III. Secondary Structure IV. Tertiary Structure V. Quaternary Structure VI. Protein Misfolding VII. Chapter Summary Study Questions

Chapter 3: Globular Proteins

I. Overview II. Globular Hemeproteins III. Globin Gene Organization IV. Hemoglobinopathies V. Chapter Summary Study Questions

Chapter 4: Fibrous Proteins

I. Overview II. Collagen III. Elastin IV. Chapter Summary Study Questions

Chapter 5: Enzymes

I. Overview II. Nomenclature III. Properties IV. Mechanism of Enzyme Action V. Factors Affecting Reaction Velocity VI. Michaelis–Menten Kinetics VII. Enzyme Inhibition VIII. Enzyme Regulation IX. Enzymes in Human Blood X. Chapter Summary Study Questions

Unit II: Bioenergetics and Carbohydrate Metabolism

Chapter 6: Bioenergetics and Oxidative Phosphorylation

I. Overview II. Free Energy III. Free Energy Change IV. ATP: An Energy Carrier V. Electron Transport Chain VI. Phosphorylation of ADP to ATP VII. Chapter Summary Study Questions

Chapter 7: Introduction to Carbohydrates

I. Overview II. Classification and Structure III. Dietary Carbohydrate Digestion IV. Chapter Summary Study Questions

Chapter 8: Introduction to Metabolism and Glycolysis

I. Metabolism Overview II. Metabolism Regulation III. Glycolysis Overview IV. Glucose Transport into Cells V. Glycolysis Reactions VI. Hormonal Regulation VII. Alternate Fates of Pyruvate VIII. Chapter Summary Study Questions

Chapter 9: Tricarboxylic Acid Cycle and Pyruvate Dehydrogenase Complex

I. Cycle Overview II. Cycle Reactions III. Energy Produced by the Cycle IV. Cycle Regulation V. Chapter Summary Study Questions

Chapter 10: Gluconeogenesis

I. Overview II. Substrates III. Reactions IV. Regulation V. Chapter Summary Study Questions

Chapter 11: Glycogen Metabolism

I. Overview II. Structure and Function III. Synthesis (Glycogenesis) IV. Degradation (Glycogenolysis) V. Glycogenesis and Glycogenolysis Regulation VI. Glycogen Storage Diseases VII. Chapter Summary Study Questions

Chapter 12: Monosaccharide and Disaccharide Metabolism

I. Overview II. Fructose Metabolism III. Galactose Metabolism IV. Lactose Synthesis V. Chapter Summary Study Questions

Chapter 13: Pentose Phosphate Pathway and Nicotinamide Adenine Dinucleotide Phosphate

I. Overview II. Irreversible Oxidative Reactions III. Reversible Nonoxidative Reactions IV. Uses of NADPH V. G6PD Deficiency VI. Chapter Summary Study Questions

Chapter 14: Glycosaminoglycans, Proteoglycans, and Glycoproteins

I. Glycosaminoglycan Overview II. Structure III. Synthesis IV. Degradation V. Mucopolysaccharidoses VI. Glycoprotein Overview VII. Oligosaccharide Structure VIII. Glycoprotein Synthesis IX. Lysosomal Glycoprotein Degradation X. Chapter Summary Study Questions

Unit III: Lipid Metabolism

Chapter 15: Dietary Lipid Metabolism

I. Overview II. Digestion, Absorption, Secretion, and Utilization III. Chapter Summary Study Questions

Chapter 16: Fatty Acid, Triacylglycerol, and Ketone Body Metabolism

I. Overview II. Fatty Acid Structure III. Fatty Acid De Novo Synthesis IV. Fat Mobilization and Fatty Acid Oxidation V. Ketone Bodies: Alternative Fuel for Cells VI. Chapter Summary Study Questions

Chapter 17: Phospholipid, Glycosphingolipid, and Eicosanoid Metabolism

I. Phospholipid Overview II. Phospholipid Structure III. Phospholipid Synthesis IV. Phospholipid Degradation V. Glycolipid Overview VI. Glycosphingolipid Structure VII. Glycosphingolipid Synthesis and Degradation VIII. Eicosanoids: Prostaglandins, Thromboxanes, and Leukotrienes IX. Chapter Summary Study Questions

Chapter 18: Cholesterol, Lipoprotein, and Steroid Metabolism

I. Overview II. Cholesterol Structure III. Cholesterol Synthesis IV. Cholesterol Degradation V. Bile Acids and Bile Salts VI. Plasma Lipoproteins VII. Steroid Hormones VIII. Chapter Summary Study Questions

Unit IV: Nitrogen Metabolism

Chapter 19: Amino Acids: Nitrogen Disposal

I. Overview II. Overall Nitrogen Metabolism III. Dietary Protein Digestion IV. Nitrogen Removal from Amino Acids V. Urea Cycle VI. Ammonia Metabolism VII. Chapter Summary Study Questions

Chapter 20: Amino Acids: Degradation and Synthesis

I. Overview II. Glucogenic and Ketogenic Amino Acids III. Amino Acid Carbon Skeleton Catabolism IV. Folic Acid and Amino Acid Metabolism V. Biosynthesis of Nonessential Amino Acids VI. Amino Acid Metabolism Disorders VII. Chapter Summary Study Questions

Chapter 21: Amino Acids: Conversion to Specialized Products

I. Overview II. Porphyrin Metabolism III. Other Nitrogen-Containing Compounds IV. Chapter Summary Study Questions

Chapter 22: Nucleotide Metabolism

I. Overview II. Structure III. Purine Nucleotide Synthesis IV. Deoxyribonucleotide Synthesis V. Purine Nucleotide Degradation VI. Pyrimidine Synthesis and Degradation VII. Chapter Summary Study Questions

Unit V: Integration of Metabolism

Chapter 23: Metabolic Effects of Insulin and Glucagon

I. Overview II. Insulin III. Glucagon IV. Hypoglycemia V. Chapter Summary Study Questions

Chapter 24: The Feed–Fast Cycle

I. Overview of the Absorptive State II. Regulatory Mechanisms III. Liver: Nutrient Distribution Center IV. Adipose Tissue: Energy Storage Depot V. Resting Skeletal Muscle VI. Brain VII. Overview of the Fasted State VIII. Liver in Fasting IX. Adipose Tissue in Fasting X. Resting Skeletal Muscle in Fasting XI. Brain in Fasting XII. Kidney in Long-Term Fasting XIII. Chapter Summary Study Questions

Chapter 25: Diabetes Mellitus

I. Overview II. Type 1 Diabetes III. Type 2 Diabetes IV. Chronic Effects and Prevention V. Chapter Summary Study Questions

Chapter 26: Obesity

I. Overview II. Assessment III. Body Weight Regulation IV. Molecular Influences V. Metabolic Effects VI. Obesity and Health VII. Weight Reduction VIII. Chapter Summary Study Questions

Unit VI: Medical Nutrition

Chapter 27: Nutrition: Overview and Macronutrients

I. Overview II. Dietary Reference Intakes III. Energy Requirement in Humans IV. Acceptable Macronutrient Distribution Ranges V. Dietary Fats VI. Dietary Carbohydrates VII. Dietary Protein VIII. Nutrition Tools IX. Nutrition and the Life Stages X. Chapter Summary Study Questions

Chapter 28: Micronutrients: Vitamins

I. Overview II. Folic Acid (Vitamin B9) III. Cobalamin (Vitamin B12) IV. Ascorbic Acid (Vitamin C) V. Pyridoxine (Vitamin B6) VI. Thiamine (Vitamin B1) VII. Niacin (Vitamin B3) VIII. Riboflavin (Vitamin B2) IX. Biotin (Vitamin B7) X. Pantothenic Acid (Vitamin B5) XI. Vitamin A XII. Vitamin D XIII. Vitamin K XIV. Vitamin E XV. Chapter Summary Study Questions

Chapter 29: Micronutrients: Minerals

I. Overview II. Macrominerals III. Trace Minerals (Microminerals) IV. Ultratrace Minerals V. Chapter Summary Study Questions

Unit VII: Storage and Expression of Genetic Information

Chapter 30: DNA Structure, Replication, and Repair

I. Overview II. DNA Structure III. Steps in Prokaryotic DNA Replication IV. Eukaryotic DNA Replication V. Eukaryotic DNA Organization VI. DNA Repair VII. Chapter Summary Study Questions

Chapter 31: RNA Structure, Synthesis, and Processing

I. Overview II. RNA Structure III. Prokaryotic Gene Transcription IV. Eukaryotic Gene Transcription V. Posttranscriptional Modification of RNA VI. Chapter Summary Study Questions

Chapter 32: Protein Synthesis

I. Overview II. The Genetic Code III. Components Required for Translation IV. Codon Recognition by Transfer RNA V. Steps in Translation VI. Co- and Posttranslational Modifications VII. Chapter Summary Study Questions

Chapter 33: Regulation of Gene Expression

I. Overview II. Regulatory Sequences and Molecules III. Regulation of Prokaryotic Gene Expression IV. Regulation of Eukaryotic Gene Expression V. Chapter Summary Study Questions

Chapter 34: Biotechnology and Human Disease

I. Overview II. Restriction Endonucleases III. DNA Cloning IV. Probes V. Southern Blotting VI. Restriction Fragment Length Polymorphism VII. Polymerase Chain Reaction VIII. Gene Expression Analysis IX. Gene Therapy X. Transgenic Animals XI. Chapter Summary Study Questions

Chapter 35: Blood Clotting

I. Overview II. Secondary Hemostasis—Fibrin Meshwork Formation III. Limiting Clotting IV. Primary Hemostasis—Platelet Plug Formation V. Chapter Summary Study Questions

Appendix Index Figure Sources

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