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Index
Cover
A Fresh Look at Anxiety Disorders
Copyright ©
Contents
Preface
Chapter 1 Risk Factors of Anxiety Disorders in Children
1. Introduction
2. Environmental risk factors
2.1. Gender
2.2. Age
2.3. Temperament
2.4. Parental factors
2.5. Culture factors
2.6. Toxic environment
2.7. A unique environmental factor and common shared environmental factor
2.8. Life experience/childhood adversities
2.9. Parental loss
2.10. Sexual abuse
2.11. Peer violence
2.12. Economical factors
3. Genetic factors
3.1. Twin studies
4. Summary
Author details
References
Chapter 2 Examining Sex and Gender Differences in Anxiety Disorders
1. Introduction
1.1. Overview of relevant studies on sex differences in anxiety disorders since 2010
2. Sex and gender differences in anxiety research
2.1. Sex differences in anxiety
2.2. Gender differences in anxiety
2.2.1. Summary and discussion of sex and gender influences in anxiety
2.3. Accounting for sex differences in anxiety severity
2.3.1. Summary and discussion of mediation studies
2.4. Sex as a moderator in anxiety research
2.4.1. Summary and discussion of moderation effects
2.5. Sex differences in clinical characteristics of anxiety disorders
2.5.1. Summary and discussion of sex differences in clinical characteristics
2.6. Sex differences in treatments of anxiety disorders
2.6.1. Pharmacotherapy
2.6.2. Psychotherapy
2.6.3. Summary and discussion of sex differences in treatment
3. Conclusion
Nomenclature
Author details
References
Chapter 3 Psychobiological Aspects of Panic Disorder
1. Introduction
2. Panic disorder diagnosis
3. Neural circuitry associated with panic disorder
4. Psychological and pharmacological interventions
5. Concluding remarks
Author details
References
Chapter 4 Genetics of Posttraumatic Stress Disorder — Candidate Genes and Their Implication in the Disease-Associated Molecular Pathomechanisms
1. Introduction
2. Genetic Studies of PTSD
2.1. Neuroendocrine system candidate genes
2.1.1. Dopaminergic system
2.1.2. Serotonergic system candidate genes
2.1.3. GABAergic system
2.1.4. HPA axis candidate genes
2.1.5. Neurotrophic factor candidate genes
2.1.6. Other candidate genes
2.2. Complement system candidate genes
2.3. Candidate genes of apoptosis
2.4. Candidate genes of synaptic plasticity
3. Conclusion
Author details
References
Chapter 5 Posttraumatic Stress Disorder Biomarker — p11
1. Introduction
2. Biomarker concept
3. Biomarker classification and application
4. Potential PTSD biomarkers
4.1. A strategy to identify a PTSD biomarker
4.2. Screening biomarker(s) for PTSD
4.3. Analytical validation of the PTSD biomarker assay
4.4. Clinical validation of the PTSD biomarker assay
5. P11 as a potential PTSD biomarker
6. Biorepository or biobank in biomarker study
7. Our biorepository and biomarker study, including p11 research
Author details
References
Chapter 6 Anxiety Disorders and Suicide: Psychiatric Interventions
1. Introduction
2. Anxiety disorders
3. Suicidal behaviors
4. Anxiety disorders and suicidal behaviors
4.1. Anxiety disorders and completed suicide: Associated factors
4.2. Anxiety disorders and attempted suicide: Associated factors
5. Specific anxiety disorders and suicidal behaviors
5.1. Panic disorder and suicide
5.2. Posttraumatic stress disorder and suicide
5.3. Obsessive-compulsive disorder and suicide
5.4. Generalized anxiety disorder and suicide
5.5. Social anxiety disorder (social phobia) and suicide
6. The comorbidity of anxiety disorders in other illnesses and suicide
6.1. The comorbidity of anxiety disorders in mood disorders and suicide
6.2. The comorbidity of anxiety disorders in bipolar disorder and suicide
6.3. The comorbidity of anxiety disorders in substance abuse and suicide
6.4. The comorbidity of anxiety disorders in schizophrenia and suicide
6.5. The comorbidity of anxiety disorders in major depression and suicide
6.6. The comorbidity of anxiety disorders in physical illness and suicide
6.7. The comorbidity of anxiety disorders in personality disorders and suicide
7. Treatment studies
8. Conclusion
Author details
References
Chapter 7 Comorbid Anxiety in Schizophrenia and Schizoaffective Disorder
1. Introduction
2. Methodology
2.1. Objectives
2.2. Sample
2.3. Measures
2.4. Procedure and design
3. Results
3.1. Correlations
3.2. Comparing treatments
3.3. Comparing IQ
4. Discussions and conclusions
Author details
References
Chapter 8 Joint Hypermobility, Anxiety, and Psychosomatics — The New Neuroconnective Phenotype
1. Introduction
2. Historical background of the relationship between joint laxity and anxiety
3. Empirical studies of the link between anxiety and collagen tissue
3.1. General diagnostic criteria of Joint Hypermobility Syndrome
3.2. Comorbidity data between anxiety and JHS
4. The role of psychosomatic mechanisms involved
5. The Neuroconnective Phenotype as a new psychosomatic phenotype
6. Anxiety disorders do relate to some somatic illnesses: measuring medical conditions in anxiety patients
7. Conclusions
Author details
References
Chapter 9 Anxiety in Natural and Surgical Menopause — Physiologic and Therapeutic Bases
1. Introduction
2. Natural and surgical menopause
3. Anxiety disorders and mood swings associated with natural or surgical menopause in women
4. Pharmacological treatment of anxiety disorders in menopausal women: Benefits versus side-effects
5. Hormonal replacement therapy
6. Antidepressants
7. Alternative therapies
8. Ovariectomized rats as an animal model for surgical menopause
References
9. Conclusion
Author details
References
Chapter 10 A Systematic Review of Anxiety Disorders following Mild, Moderate and Severe TBI in Children and Adolescents
1. Introduction
2. Defining traumatic brain injury
2.1. Research findings
2.2. Rationale and aims
2.3. Comparison of merit of studies with criteria from Satz (2001)
3. Method
4. Results
4.1. Anxiety disorders following TBI in children and adolescents
4.2. Neural substrates and brain regions associated with anxiety following TBI
5. Discussion
5.1. Methodological concerns
5.2. Other concerns
5.3. Practical implications
5.4. Limitations
5.5. Future directions and conclusions
Author details
References
Chapter 11 Impact of Anxiety and Depression Symptoms on Scholar Performance in High School and University Students
1. Introduction
2. Anxiety and depression
2.1. Concept
3. Anxiety and depression in adolescents
3.1. Anxiety
3.2. Depression
4. Diagnosis
5. Treatment
6. Social problems associated with anxiety and depression
7. Academic achievement
8. Conclusion
Author details
References
Chapter 12 The Role of Expectations in Treatment Outcome and Symptom Development in Anxiety Disorders
1. Introduction
2. Expectations in mental health
2.1. Prognostic expectations
2.1.1. Shifts in prognostic expectations
2.2. Process expectations
2.2.1. Participants' role in therapy
2.2.2. Therapeutic process and procedures
3. Expectations and anxiety disorders
3.1. Expectancy of a fearful response
3.2. Anxiety sensitivity
4. Conclusion
Author details
References
Chapter 13 Practical Applications of Complementary and Alternative Therapies in Adults and Youth with Anxiety Disorders
1. Introduction
2. What Is CAM?
3. Prevalence of CAM use
4. Safety
5. Effectiveness
6. Practical applications
6.1. Case study 1
6.2. Case study 2
6.3. Case study 3
6.4. Case study 4
Author details
References
Chapter 14 Yoga for Anxiety Management in the Workplace
1. Introduction
2. Work, a question of balance and psychosocial aspects
3. Workplace and anxiety
3.1. Burn out, source of stress in workplaces
3.2. The importance of stress prevention in working organization
3.3. Mental disorders in the EU, the importance of an early intervention
3.4. Yoga: A biopsychosocial approach to health
3.5. Yoga and work organization
4. Two studies focused on yoga and health — The Milan “Fatebenefratelli e Oftalmico” Hospital experience
4.1. SKY for anxiety disorders
4.2. Yoga, meditation, and mantras to deal with work-related stress for employees of a hospital
5. Conclusion
Author details
References
Chapter 15 Mindfulness — New Research and Treatment Directions in Post-traumatic Stress Disorder
1. Introduction
2. Mindfulness — The ”Third Wave” in cognitive behavior therapies
3. The neuroscience of mindfulness and its implications in PTSD
4. The mechanism of mindfulness
4.1. Measuring and operationalization mindfulness
4.2. The Influence of Mindfulness on PTSD Cognitive Processes
4.2.1. Mindfulness, memory, and attention
4.2.2. Mindfulness and acceptance
4.3. Mindfulness versus hypnosis, traditional meditation, and relaxation
4.3.1. Mindfulness and hypnosis
4.3.2. Mindfulness and traditional meditation
4.3.3. Mindfulness and relaxation training
5. Conclusions and discussions
Author details
References
Chapter 16 Anxiety — Is There an App for That? Considering Technology, Psychiatry, and Internet-Assisted Cognitive Behavioral Therapy
1. Introduction
2. Evidence for ICBT
3. Clinical Implementation: Australia
4. Advantages of ICBT
5. Disadvantages of ICBT
6. ICBT resources available
7. Challenges and future directions
8. Conclusions
Author details
References
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