The Inflamed Mind by Bullmore, Edward -- Read -- Imperial Library of Trantor

Index

Cover Dedication Preface Chapter 1: Daring to think differently

Root canal blues Neuro-immunology and immuno-psychiatry What does an inflamed mind look like? The revolution will not be televised

Chapter 2: The workings of the immune system

Inflammation and infection

Fig 1. Immune cells Fig 2. Inflammation

Location, location, location Communication: the medium is the message

Fig 3. The immune system

Rapid rebuttal and learning Auto-immunity: the flip side

Chapter 3: Hiding in plain sight

It’s depressing being ill The cogito, God, and the machine

A long shadow Mrs P is not alone A bona fide blockbuster The Cartesian blind spot

Chapter 4: Melancholia after Descartes

From black bile to MDD A cross to bear Super-shrink

Fig 5. Freud’s first draft of the ego

Dancing in the sanatorium

Fig 6. First prophet of pharmaceuticals

The golden age

Fig 7. Scenes of joy at the dawn of anti-depressants Fig 8. The seer and the synapse

Farcical serotonin Bereft of biomarkers

Chapter 5: How?

Extraordinary claims demand extraordinary evidence A stubborn fact Causes must come first The Berlin Wall in the brain

Inflamed brains

Chapter 6: Why?

What could make you inflamed (and depressed)? Flaming stressed Causal chains and cycles Ultimately, the answer must always be Darwin

Fig 11. Emotional faces and emotional brains

A savannah survival story

Chapter 7: So what?

Medical apartheid

Could it be different already? Market failure Beyond blockbusters: better but not bigger than Prozac Alzheimer’s disease and the yin and yang of microglia Schizophrenia and auto-intoxication

Acknowledgements Disclaimers About the Author References Index Copyright