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Index
Cover image
Title page
Table of Contents
Copyright
Contributors
Preface
Chapter One: Thiamin
Abstract
1 Introduction
2 Diet and Environmental Stress
3 Symptoms and Signs in Beriberi
4 The Discovery of Thiamin
5 Thiaminase
6 Thiamin Transporters
7 Guanylate Cyclase
8 Laboratory Studies for Thiamin Deficiency
9 Diseases Related to Thiamin Metabolism
10 Thiamin Deficiency Induces Genetic Changes
11 Nitric Oxide
12 Thiamin in Clinical Practice
13 Thiamin-Responsive Mutations
14 Thiamin Administered With Analgesics
15 Thiamin Deficiency After Surgery
16 Thiamin Deficiency Dysautonomia
17 Thiamin in Obstetrics
18 Autism
19 Thiamin Derivatives
20 Unusual Case Reports
21 Conclusion
22 A Question of Historical Significance
Chapter Two: Riboflavin in Human Health: A Review of Current Evidences
Abstract
1 Riboflavin at a Glance
2 Antioxidant Properties of Riboflavin
3 Riboflavin and Cancer
4 Riboflavin as a Neuroprotective Agent
Chapter Three: Niacin
Abstract
1 Introduction
2 Role of Dietary Niacin in Disease Origin and Progression
3 NAD Metabolism
4 NAD: Relevance to Health and Disease
5 Summary
Chapter Four: The Emerging Role of Vitamin B6 in Inflammation and Carcinogenesis
Abstract
1 Introduction
2 Role of B6 in Oxidative Stress and Inflammation
3 Indirect Role of B6, Acting as a Coenzyme and Production of Biologically Active H2S and Taurine
4 B6 and Carcinogenesis
5 Future Perspective
Acknowledgments
Chapter Five: Recent Developments in Folate Nutrition
Abstract
1 Introduction
2 Folate and Folic Acid
3 Summary
Chapter Six: Vitamin B12
Abstract
1 Introduction
2 Biochemistry of Vitamin B12
3 Poor B12 Status: Deficiency or Inadequacy?
4 Clinical Relevance of B12 Inadequacy/Insufficiency
5 B12 Status and Neurological and Cognitive Functioning in Adults
6 Poor B12 Status in Mother and Child: Health Outcomes
7 How Does the Brain Mediate the Effects of B12 on Cognition?
8 Conclusions
Chapter Seven: Dietary Vitamin C in Human Health
Abstract
1 Introduction
2 Vitamin C: Basic Physiology
3 Current Benchmarks of Vitamin C Status and Dietary Recommendations
4 Vitamin C Status in the General Population
5 Genetic Influences on Vitamin C Metabolism and Disease Pathology
Chapter Eight: Water-Soluble Vitamin E—Tocopheryl Phosphate
Abstract
1 Introduction
2 Water-Soluble Vitamin Analogues
3 Early Studies With α-Tocopheryl Phosphate
4 Induction of Apoptosis by α-Tocopheryl Phosphate
5 Methods of Isolation and Detection of α-Tocopheryl Phosphate
6 Bioavailability of α-Tocopheryl Phosphate
7 Modulation of Signal Transduction and Gene Expression by α-Tocopheryl Phosphate
8 Molecular Mechanisms of α-Tocopheryl Phosphate Action
9 Animal and Human Studies With α-Tocopheryl Phosphate
10 Possible Mechanisms of Disease Prevention by α-Tocopheryl Phosphate
11 Potential Uses of α-Tocopheryl Phosphate and of Its Analogs and Derivatives
12 Conclusions
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