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Index
Dedication
Title page
Copyright page
Preface
Acknowledgements
Chapter 1: Introduction
A brief history of food safety
Evolution of cellular protection mechanisms
Chapter 2: Food Risk
What is risk?
Measuring hazard
Determining risk
Acceptable risk
Risk versus benefit
Risk perception
The precautionary principle
Food risk assessment
Relative risk and risk ranking
Risk management
Risk communication
Quantitative risk assessment
Take home messages
Chapter 3: Bacteria
The discovery of bacteria
The biology of bacteria
The bacterial ecology of food
Human bacterial pathogens on food
Gastroenteritis
Food-borne pathogenic bacteria
Take home messages
Chapter 4: Viruses
The discovery of viruses
The biology of viruses
Diseases caused by viruses and mechanisms of viral transmission
Other food-borne viruses
Take home messages
Chapter 5: Parasites
What are parasites?
Flatworms – Platyhelminthes
Tapeworms – Cestodes
Flukes – Trematodes
Nematodes
Protozoa
Take home messages
Chapter 6: Bovine Spongiform Encephalopathy (BSE)
The history of BSE
The epidemiology of BSE in England
Spongiform encephalopathies
Prions
The symptoms of BSE
BSE cases in the UK
BSE transmission and the origins of PrPSC
The risk to human consumers of BSE beef – nvCJD
The politics of BSE and implications for food safety worldwide
BSE incidence around the world
Take home messages
Chapter 7: Chemical Contaminants
Pesticides
Insecticides
Herbicides
Fungicides
Veterinary medicines
Growth promoting chemicals
Fertilisers
Natural environmental chemicals
Non-agricultural environmental pollutants
Residues monitoring programmes
Dietary intake and risk to human consumers
Take home messages
Chapter 8: Natural Toxins
Why produce natural toxins?
Natural toxins in the human food chain
Plant toxins
Mycotoxins
Phytohaemagglutinins in beans
Bacterial toxins
Phytoestrogens
Take home messages
Chapter 9: Endocrine Disrupting Chemicals
The first observations of xenoestrogens’ effects
Estrogen receptors – ERs
Molecular requirements for estrogenicity
Estrogens are present in both males and females
Xenoestrogens
Population level effects of exposure to xenoestrogens
The positive health effects of xenoestrogens
Take home messages
Chapter 10: Genetically Modified Food
A brief introduction to nucleic acids, genetics and molecular biology
Nucleic acids
Converting the genetic code into a protein
The history of GM crops
The tools of the genetic engineer
Glyphosate-resistant crops
Insect-protected crops – BT toxin
GM crops with enhanced flavour or nutritional properties
What happens if humans eat GM crops or foods made from them?
Changed biochemistry in GM crops
What is the effect of eating DNA and RNA?
GM animals
Take home messages
Chapter 11: Colours, Flavours and Preservatives
Food colours
Flavours
Preservatives
Take home messages
Chapter 12: Food Irradiation
Different types of radioactivity
How irradiation kills cells
The history of food irradiation
The effect of radiation on microorganisms
How is food irradiated?
The effects of irradiation on food chemistry
The effects of irradiation on vitamins
Radiation dose
Does irradiation make food radioactive?
Health effects of food irradiation
The use of food irradiation around the world
Take home messages
Chapter 13: Food Safety and the Unborn Child
‘You are what your mother ate’
Growth and development of the embryo and fetus
Effects of food chemical contaminants
Effects of microbiological contaminants
Effects on ova and sperm
Take home messages
Chapter 14: Organic Food
What does ‘organic’ mean?
The history and philosophy of organic farming
Demand for organic food
Organic farming methods
Organic farming legislation
Organic fertilisers
Organic pest control
Organic weed control
Animal health remedies
Food processing
Is organic food better for you?
Myths and facts about organic food
Take home messages
Chapter 15: Food Allergy
What is an allergy?
The basics of immunology
Immunity and the immune response
Sensitisation
Food allergies
The genetics of allergy
Food allergens
Milk allergy
Peanut allergy
Soy allergy
Nut allergies
Seafood allergies
Gluten allergy (coeliac disease)
Allergy to eggs
Allergen cross-reactivity
Banana/latex allergy
Food additives allergy
Why is the incidence of food allergies increasing?
A cautionary note
Take home messages
Chapter 16: Food Legislation
Legal processes – how laws are made
A very brief history of food law
Food legislation around the world
Food legislation in the USA
Food legislation in the UK
Food legislation in New Zealand
Policing food legislation
Does food legislation reduce risks to consumers?
Case example – non-compliance follow-up
The relevance of national food legislation in a global food market
Take home messages
Index
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