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Index
Cover
Overview
Title
Copyright
Dedication
Preface
Contents
1. Fundamentals
Microscopic Anatomy of the Nervous System
Elements of Neurophysiology
Elements of Neurogenetics
General Genetics
Neurogenetics
Genetic Counseling
2. The Clinical Interview in Neurology
General Principles of History Taking
Special Aspects of History Taking
3. The Neurological Examination
Basic Principles of the Neurological Examination
Stance and Gait
Examination of the Head and Cranial Nerves
Head and Cervical Spine
Cranial Nerves
Examination of the Upper Limbs
Motor Function and Coordination
Muscle Tone and Strength
Reflexes
Sensation
Examination of the Trunk
Examination of the Lower Limbs
Coordination and Strength
Reflexes
Sensation
Examination of the Autonomic Nervous System
Neurologically Relevant Aspects of the General Physical Examination
Neuropsychological and Psychiatric Examination
Psychopathological Findings
Neuropsychological Examination
Special Considerations in the Neurological Examination of Infants and Younq Children
Reflexes
4. Ancillary Tests in Neurology
Fundamentals
Imaging Studies
Conventional Skeletal Radiographs
Computed Tomography (CT)
Magnetic Resonance Imaging (MRI)
Angiography with Radiological Contrast Media
Myelography and Radiculography
Diagnostic Techniques of Nuclear Medicine
Electrophysiological Studies
Fundamentals
Electroencephalography (EEC)
Evoked potentials
Electromyography
Electroneurography
Other Electrophysiological Studies
Ultrasonography
Other Ancillary Studies
Cerebrospinal Fluid Studies
Tissue Biopsies
Perimetry
5. Topical Diagnosis and Differential Diagnosis of Neurological Syndromes
Fundamentals
Muscle Weakness and Other Motor Disturbances
Anatomical Substrate of Motor Function
Sensory Disturbances
Anatomical Substrate of Sensation
Disturbances of Consciousness
Dysfunction of Specific Areas of the Brain
Syndromes of the Individual Lobes of the Cerebral Hemispheres
Syndromes of the Extrapyramidal Motor System
Thalamic Syndromes
Brainstem Syndromes
Cerebellar Syndromes
6. Diseases of the Brain and Meninges
Congenital and Perinatally Acquired Diseases of the Brain
Fundamentals
Special Clinical Forms
Traumatic Brain injury
Fundamentals
Relevant Aspects of the Clinical History and Neurological Examination
Grades of Severity of Traumatic Brain Injury
Traumatic Hematomas
Complications of Traumatic Brain Injury
Intracranial Pressure and Brain Tumors
Intracranial Pressure
Brain Tumors
Circulatory Disorders of the Brain and Nontraumatic Intracranial Hemorrhage
Cerebral Ischemia
Nontraumatic Intracranial Hemorrhage
Infectious Diseases of the Brain and Meninges
Infections Mainly Involving the Meninges
Infections Mainly Involving the Brain
Intracranial Abscesses
Metabolic Disorders and Systemic Illnesses Affecting the Nervous System
Congenital Metabolic Disorders
Acquired Metabolic Disorders
Diseases of the Basal Ganglia
Fundamentals
Diseases Causing Hypertonia and Hypokinesia
Degenerative Systemic Diseases Causing Hypertonia and Hypokinesia
Diseases Causing Hyperkinesia
Other Types of Involuntary Movement
Cerebellar Diseases
The More Common Diseases of the Cerebellum
Dementing Diseases
The Dementia Syndrome
Degenerative Brain Diseases Causing Dementia as Their Most Prominent Manifestation
Vascular Dementia
7. Diseases of the Spinal Cord
Anatomical Fundamentals
The Main Spinal Cord Syndromes and Their Anatomical Localization
Spinal Cord Trauma
Spinal Cord Compression
Spinal Cord Tumors
Myelopathy Due to Cervical Spondylosis
Circulatory Disorders of the Spinal Cord
Blood Supply of the Spinal Cord
Arterial Hypoperfusion
Impaired Venous Drainage
Hemorrhage in or Adjacent to the Spinal Cord
Infectious and Inflammatory Diseases of the Spinal Cord
Syringomyelia and Syringobulbia
Diseases Mainly Affecting the Long Tracts of the Spinal Cord
Hereditary Diseases of the Long Tracts of the Spinal Cord
Diseases of the Anterior Horns
8. Multiple Sclerosis and Other Myelinopathies
Fundamentals
Myelin
Multiple Sclerosis
Other Demyelinating Diseases of Unknown Pathogenesis
9. Epilepsy and Its Differential Diagnosis
Types of Epilepsy
Classification of the Epilepsies
Practical Clinical Management of a Suspected Epileptic Seizure
Generalized Seizures
Partial (Focal) Seizures
Status Epilepticus
Episodic Neurological Disturbances of Nonepileptic Origin
Episodic Disturbances with Transient Loss of Consciousness and Falling
Episodic Falling without Loss of Consciousness
Episodic Loss of Consciousness without Falling
Episodic Movement Disorders without Loss of Consciousness
10. Polyradiculopathy and Polyneuropathy
Fundamentals
Polyradiculitis
Classic Polyradiculitis (Landry–Guillain–Barré–Strohl Syndrome)
Chronic Inflammatory Demyelinating (Recurrent) Polyneuropathy (CIDP)
Cranial Polyradiculitis
Polyradiculitis of the Cauda Equina
Polyneuropathy
Fundamentals
Particular Etiologic Types of Polyneuropathy
11. Diseases of the Cranial Nerves
Fundamentals
Disturbances of Smell (Olfactory Nerve)
Neurological Disturbances of Vision (Optic Nerve)
Visual Field Defects
Impairment of Visual Acuity
Pathological Findings of the Optic Disc
Disturbances of Ocular and Pupillary Motility
Fundamentals of Eye Movements
Oculomotor Disturbances
Supranuclear Oculomotor Disturbances
Lesions of the Nerves to the Eye Muscles and Their Brainstem Nuclei
Ptosis
Pupillary Disturbances
Lesions of the Trigeminal Nerve
Lesions of the Facial Nerve
Disturbances of Hearing and Balance; Vertigo
Neurological Disturbances of Hearing
Disequilibrium and Vertigo
The Lower Cranial Nerves
Lesions of the Glossopharyngeal and Vagus Nerves
Accessory Nerve Palsy
Hypoglossal Nerve Palsy
Multiple Cranial Nerve Deficits
12. Diseases of the Spinal Nerve Roots and Peripheral Nerves
Fundamentals
Spinal Radicular Syndromes
Radicular Syndromes Due to Intervertebral Disk Herniation
Radicular Syndromes Due to Spinal Stenosis
Radicular Syndromes Due to Space-Occupying Lesions
Peripheral Nerve Lesions
Fundamentals
Diseases of the Brachial Plexus
Diseases of the Peripheral Nerves of the Upper Limbs
Diseases of the Nerves of the Trunk
Diseases of the Lumbosacral Plexus
Diseases of the Peripheral Nerves of the Lower Limbs
13. Painful Syndromes
Fundamentals
Painful Syndromes of the Head And Neck
IHS Classification of Headache
Approach to the Patient with Headache
Migraine
Cluster Headache
Tension-type Headache
Rare Varieties of Primary headache
Symptomatic Headache
Painful Syndromes of the Face
Dangerous Types of Headache
“Genuine” Neuralgias in the Face
Other Diseases Causing Facial Pain
General Differential Diagnosis of Headache and Facial Pain
Painful Shoulder–Arm Syndromes (SAS)
Spondylogenic (Cervicogenic) Shoulder and Arm Pain
Degenerative and Rheumatic Shoulder and Arm Pain
Neurogenic Arm Pain
Vasogenic Arm Pain
Pain in the Trunk and Back
“Arm Pain of Overuse”
Other Types of Arm Pain
Thoracic and Abdominal Wall Pain
Back Pain
Leg Pain
Groin Pain
Pseudoradicular Pain
14. Diseases of Muscle (Myopathies)
Structure and Function of Muscle
General Symptomatology, Evaluation, and Classification of Muscle Diseases
Muscular Dystrophies
Hereditary Muscular Dystrophies of X-chromosomal Inheritance-Dystrophinopathies
Autosomal Muscular Dystrophies
Myotonic Syndromes and Periodic Paralysis Syndromes
Rarer Types of Muscular Dystrophy
Diseases Mainly Causing Myotonia
Diseases Causing Periodic Paralysis
Metabolic Myopathies
Acute Rhabdomyolysis
Mitochondrial Encephalomyopathies
Myositis
Other Diseases Affecting Muscle
Myopathies Due to Systemic Disease
Congenital Myopathies
Disturbances of Neuromuscular Transmission-Myasthenic Syndromes
15. Diseases of the Autonomic Nervous System
Anatomy
Normal and Pathological Function of the Autonomic Nervous System
Sweating
Bladder, Bowel, and Sexual Function
The Cervical Sympathetic Pathway and Horner Syndrome
Generalized Autonomic Dysfunction
Index
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