Log In
Or create an account -> 
Imperial Library
  • Home
  • About
  • News
  • Upload
  • Forum
  • Help
  • Login/SignUp

Index
Cover Table of Contents Dedication Title page Copyright page About the Authors Contributors Preface and Acknowledgments How to Use Your Textbook
Features Contained within Your Textbook The Anytime, Anywhere Textbook
About the Companion Website 1: Overview of the Immune System
Introduction Innate and Adaptive Immunity Clonal Selection Theory Active, Passive, and Adoptive Immunization Humoral and Cellular Immunity Cell-Mediated Immunity Generation of Diversity in the Immune Response Benefits of Immunology Damaging Effects of the Immune Response The Future of Immunology The Short Course Begins Here References and Bibliography
2: Innate Immunity
Introduction Physical and Chemical Barriers of Innate Immunity Pattern Recognition: The Hallmark of Innate Immune Responses Complement Inflammation References and Bibliography Review Questions Answers to Review Questions
3: Adaptive Immunity
Cells and Organs Involved in Adaptive Immunity The Fate of Antigen after Penetration Interrelationship between Innate and Adaptive Immunity Review Questions Answers to Review Questions
4: Immunogens and Antigens
Introduction Requirements for Immunogenicity Primary and Secondary Responses Antigenicity and Antigen-Binding Site Epitopes Recognized by B Cells and T Cells Major Classes of Antigens Binding of Antigen with Antigen-Specific Antibodies or T Cells Cross-Reactivity Adjuvants References and Bibliography Review Questions Answers to Review Questions
5: Antibody Structure and Function
Introduction Isolation and Characterization of Immunoglobulins Structure of Light and Heavy Chains Domains Hinge Region Variable Region Immunoglobulin Variants Structural Features of IgG Structural Features of IgM Biologic Properties of IgM Structural and Biologic Properties of IgA Structural and Biologic Properties of IgD Structural and Biologic Properties of IgE Kinetics of the Antibody Response Following Immunization The Immunoglobulin Superfamily References and Bibliography Review Questions Answers to Review Questions
6: Antigen–Antibody Interactions, Immune Assays, and Experimental Systems
Introduction Antigen–Antibody Interactions Primary Interactions Between Antibody and Antigen Secondary Interactions between Antibody and Antigen Immunoassays Immunofluorescence Flow Cytometry Immunoabsorption and Immunoadsorption Cellular Assays Cell Culture Experimental Animal Models Transgenic Mice and Gene Targeting Analysis of Gene Expression References and Bibliography Review Questions Answers to Review Questions
7: The Genetic Basis of Antibody Structure
Introduction A Brief Review of Nonimmunoglobulin Gene Structure and Gene Expression Genetic Events in Synthesis of Ig Chains Class or Isotype Switching Generation of Antibody Diversity Role of Activation-Induced Cytidine Deaminase in Generating Antibody Diversity References and Bibliography Review Questions Answers to Review Questions
8: Biology of the B Lymphocyte
Introduction Development of B Lymphocytes Sites of Antibody Synthesis B-Cell Membrane Proteins References and Bibliography Review Questions Answers to Review Questions
9: How T Cells Recognize Antigen: The Role of the Major Histocompatibility Complex
Introduction How The MHC Got Its Name MHC Role in Antigen Presentation Different MHC Molecules Are Expressed by Distinct Host Cells and Interact with Different Sets of T Cells Variability of MHC Class I and MHC Class II Molecules Structure of MHC Class I and Class II Molecules Antigen Processing and Presentation: How MHC Molecules Bind Peptides and Create Ligands That Interact with T Cells Other Types of Antigen That Activate T-Cell Responses Genes of the HLA Region Nomenclature of Polymorphic MHC Molecules Regulation of Expression of MHC Genes MHC in Other Species Diversity of MHC Molecules: MHC Association with Resistance and Susceptibility to Disease References and Bibliography Review Questions Answers to Review Questions
10: Biology of the T Lymphocyte
Introduction The Antigen-Specific T-Cell Receptor Genes Coding for T-Cell Receptors Generation of T-Cell Receptor Diversity T-Cell Differentiation in the Thymus References and Bibliography Review Questions Answers to Review Questions
11: Activation and Function of T Cells
Introduction A Two-Signal Model for the Activation of T Cells Dendritic Cells Are the Key APC for Naïve T Cells Activation of CD4+ T Cells CD4+ T-Cell Function Activation and Function of CD8+ T Cells CD8+ T-Cell Killing of Target Cells Memory T Cells Function of Other Subsets of T Cells References and Bibliography Review Questions Answers to Review Questions
12: Cytokines
Introduction The History of Cytokines General Properties of Cytokines Functional Categories of Cytokines Cytokine Receptors Cytokine Receptor-Mediated Signal Transduction Role of Cytokines and Cytokine Receptors in Disease Therapeutic Exploitation of Cytokines and Cytokine Receptors References and Bibliography Review Questions Answers to Review Questions
13: Tolerance and Autoimmunity
Introduction Central Tolerance Peripheral Tolerance Oral Tolerance Immune Privilege Autoimmunity and Disease Autoimmune Diseases References and Bibliography Review Questions Answers to Review Questions
14: Complement
Introduction Overview of Complement Activation Regulation of Complement Activity Biologic Activities of Complement Complement Deficiencies References and Bibliography Review Questions Answers to Review Questions
15: Hypersensitivity: Type I
Introduction General Characteristics of Allergic Reactions Sensitization Phase Activation Phase Effector Phase Clinical Aspects of Allergic Reactions Clinical Tests for Allergies and Clinical Intervention Intervention The Protective Role of IgE References and Bibliography Review Questions Answers to Review Questions
16: Hypersensitivity: Types II and III
Introduction Type II Hypersensitivity Examples of Type II Hypersensitivity Reactions References and Bibliography Review Questions Answers to Review Questions
17: Hypersensitivity: Type IV
Introduction General Characteristics and Pathophysiology of DTH Examples of DTH Treatment of DTH References and Bibliography Review Questions Answers to Review Questions
18: Immunodeficiency Disorders and Neoplasias of the Lymphoid System
Introduction Immunodeficiency Syndromes Acquired Immunodeficiency Syndrome Neoplasms of Lymphoid System References and Bibliography Review Questions Answers to Review Questions
19: Transplantation
Introduction Relationship between Donor and Recipient Immune Mechanisms are Responsible for Allograft Rejection Categories of Allograft Rejection Role of MHC Molecules in Allograft Rejection Role of T Cell Lineages and Cytokines in Allograft Rejection Laboratory Tests Used in Tissue Typing Prolongation of Allograft Survival: Immunosuppresive Therapy Hematopoietic Stem Cell Transplantation Graft-Versus-Host Disease Xenogeneic Transplantation The Fetus: A Tolerated Allograft References and Bibliography Review Questions Answers to Review Questions
20: Tumor Immunology
Introduction Tumor Antigens Categories of Tumor Antigens Immunologic Factors Influencing the Incidence of Cancer Effector Mechanisms in Tumor Immunity Cell-Mediated Responses to Tumor Cells Cytokines Limitations of the Effectiveness of The Immune Response Against Tumors Immunodiagnosis Tumor Immunoprophylaxis Immunotherapy References And Bibliography Review Questions Answers To Review Questions
21: Resistance and Immunization to Infectious Diseases
Introduction Host Defense Against the Various Classes of Microbial Pathogens Mechanisms by Which Pathogens Evade the Immune Response Principles of Immunization Objectives of Immunization Active Immunizations Basic Mechanisms of Protection Vaccine Precautions Recent Approaches to Production of Vaccines Passive Immunization References and Bibliography Review Questions Answers to Review Questions
Glossary Appendix: Partial List of CD Antigens Index End User License Agreement
  • ← Prev
  • Back
  • Next →
  • ← Prev
  • Back
  • Next →

Chief Librarian: Las Zenow <zenow@riseup.net>
Fork the source code from gitlab
.

This is a mirror of the Tor onion service:
http://kx5thpx2olielkihfyo4jgjqfb7zx7wxr3sd4xzt26ochei4m6f7tayd.onion