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Index
Cover Frontmatter 1. Introduction 1. Brief Historical Note
2. A Brief History of the Cerebellum 3. Pivotal Insights: The Contributions of Gordon Holmes (1876–1965) and Olof Larsell (1886–1964) to Our Understanding of Cerebellar Function and Structure
2. Anatomy and Histology of the Cerebellum
4. Gross Anatomy of the Cerebellum 5. Vascular Supply and Territories of the Cerebellum 6. The Olivocerebellar Tract 7. Precerebellar Nuclei 8. Vestibular Nuclei and Their Cerebellar Connections 9. Spinocerebellar and Cerebellospinal Pathways 10. Visual Circuits 11. The Cerebrocerebellar System 12. Cerebello-Cerebral Feedback Projections
3. Embryology and Development of the Cerebellum
13. Cerebellar Neurogenesis 14. Zones and Stripes 15. Specification of Cerebellar Neurons 16. Cerebellar Nucleus Development 17. Development of Glutamatergic and GABAergic Synapses 18. Synaptogenesis and Synapse Elimination in Developing Cerebellum 19. Cerebellar Epigenetics: Transcription of MicroRNAs in Purkinje Cells
4. Cerebellar Circuits: Biochemistry, Neurotransmitters and Neuromodulation
20. Granule Cells and Parallel Fibers 21. The Purkinje Cell: As an Integrative Machine 22. Stellate Cells 23. Basket Cells 24. Golgi Neurons 25. Lugaro Cells 26. Unipolar Brush Cells 27. Glial Cells 28. GABA Pathways and Receptors 29. Glutamatergic Pathways and Receptors 30. Norepinephrine and Synaptic Transmission in the Cerebellum 31. Serotonin in the Cerebellum 32. Nitric Oxide 33. Cerebellar Circuits: Biochemistry, Neurotransmitters and Neuromodulators 34. Purinergic Signalling in the Cerebellum 35. Neuropeptides in the Cerebellum 36. Neurosteroids 37. Cerebellar Modules and Networks Involved in Locomotion Control 38. Distributed Plasticity in the Cerebellar Circuit
5. Basic Physiology
39. Oscillation in the Inferior Olive Neurons: Functional Implication 40. Simple Spikes and Complex Spikes 41. Rebound Depolarization and Potentiation 42. Cerebellar Nuclei 43. Plasticity of the Cerebellum 44. Physiology of Olivo-Cerebellar Loops 45. Long-Term Depression at Parallel Fiber-Purkinje Cell Synapses 46. Regulation of Calcium in the Cerebellum
6. Neuroimaging of the Cerebellum
47. Cerebellar Closed-Loops 48. MRI Aspects: Conventional, SWI, DTI 49. SPECT and PET 50. MR Spectroscopy 51. Functional Topography of the Human Cerebellum
7. Functional Properties of the Cerebellum
52. Cerebro-Cerebellar Networks 53. Clinical Functional Topography in Cognition 54. Sequencing 55. Speech and Language
8. Cellular and Animal Models of Cerebellar Disorders
56. The Zebrafish Cerebellum 57. The Teleost Fish 58. Lurcher Mouse 59. The Tottering Mouse 60. The Rolling Nagoya Mouse 61. Ataxic Syrian Hamster 62. Lesions of the Cerebellum 63. Cellular and Animal Models of Cerebellar Disorders: Staggerer Mouse
9. Human Cerebellar Symptoms: From Movement to Cognition
64. Cerebellum and Oculomotor Deficits 65. Speech Deficits 66. Deficits of Limbs Movements 67. Lesion-Symptom Mapping 68. The Cerebellar Cognitive Affective Syndrome and the Neuropsychiatry of the Cerebellum 69. Ataxia Scales for the Clinical Evaluation
10. Human Cerebellar Disorders: From Prenatal Period to Elderly
70. Differential Diagnosis of Cerebellar Ataxias on the Basis of the Age at Onset 71. Overview of Ataxias in Children 72. Cerebellar Pathology in Autism 73. Autosomal Recessive Ataxias 74. X-Linked Ataxias 75. Imaging of Malformations of the Hindbrain and Craniocervical Junction 76. Cerebellar Stroke 77. Immune Diseases 78. Paraneoplastic Cerebellar Degeneration 79. Essential Tremor 80. Toxic Agents 81. Endocrine Disorders
11. Therapies of Cerebellar Ataxias
82. Drugs in Selected Ataxias 83. Cerebellar Stimulation 84. Motor Rehabilitation of Cerebellar Disorders
Backmatter
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