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Index
Cover
Title Page
Front Matter
Dedication
Copyright
Preface
Drug dosage and nomenclature
Table of Contents
1: General principles
Principles of pharmacology and mechanisms of drug action
Pharmacokinetics
Drug discovery, safety and efficacy
The nervous system, neurotransmission and the peripheral autonomic nervous system
2: The cardiovascular system
Ischaemic heart disease
Systemic and pulmonary hypertension
Heart failure
Cardiac arrhythmias
Cerebrovascular disease and dementia
Peripheral vascular disease
Haemostasis
3: The respiratory system
Asthma and chronic obstructive pulmonary disease
Respiratory disorders: Cough, respiratory stimulants, cystic fibrosis and neonatal respiratory distress syndrome
4: The renal system
Diuretics
Disorders of micturition
Erectile dysfunction
5: The nervous system
General anaesthetics
Local anaesthetics
Opioid analgesics and the management of pain
Anxiolytics, sedatives and hypnotics
The major psychotic disorders: Schizophrenia and mania
Depression, attention deficit hyperactivity disorder and narcolepsy
Epilepsy
Extrapyramidal movement disorders and spasticity
Other neurological disorders: Multiple sclerosis, motor neuron disease and Guillain–Barré syndrome
Migraine
6: The musculoskeletal system
The neuromuscular junction and neuromuscular blockade
Myasthenia gravis
Non-steroidal anti-inflammatory drugs
Rheumatoid arthritis, other inflammatory arthritides and osteoarthritis
Hyperuricaemia and gout
7: The gastrointestinal system
Nausea and vomiting
Dyspepsia and peptic ulcer disease
Inflammatory bowel disease
Constipation, diarrhoea and irritable bowel syndrome
Liver disease
Obesity
8: The immune system
The immune response and immunosuppressant drugs
Antihistamines and allergic disease
9: The endocrine system and metabolism
Diabetes mellitus
The thyroid and control of metabolic rate
Calcium metabolism and metabolic bone disease
Pituitary and hypothalamic hormones
Corticosteroids (glucocorticoids and mineralocorticoids)
Female reproduction
Androgens and anabolic steroids
Anaemia and haematopoietic colony-stimulating factors
Lipid disorders
10: The skin and eyes
Skin disorders
The eye
11: Chemotherapy
Chemotherapy of infections
Chemotherapy of malignancy
12: General features: toxicity and prescribing
Drug toxicity and overdose
Substance abuse and dependence
Prescribing, adherence and information about medicines
Drug therapy in special situations
Index
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