CONTENTS

1. Cover
2. Title Page
3. Copyright
4. Dedication
5. Preface
6. Chapter 1    Begley’s Bombshell
7. Chapter 2    It’s Hard Even on the Good Days
8. Chapter 3    A Bucket of Cold Water
9. Chapter 4    Misled by Mice
10. Chapter 5    Trusting the Untrustworthy
11. Chapter 6    Jumping to Conclusions
12. Chapter 7    Show Your Work
13. Chapter 8    A Broken Culture
14. Chapter 9    The Challenge of Precision Medicine
15. Chapter 10  Inventing a Discipline
16. Acknowledgments
17. About the Author
18. Notes
19. Index