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Index
Cover
Frontmatter
1. Etiology and Pathogenesis
1. Genetics of Inflammatory Bowel Diseases
2. The Intestinal Immune System During Homeostasis and Inflammatory Bowel Disease
3. Cytokines and Inflammatory Bowel Disease
4. The Gut Microbiota and Inflammatory Bowel Disease
5. Immune Dysregulation Associated with Very Early-Onset Inflammatory Bowel Disease
2. Epidemiology and Clinical Features
6. Epidemiology of Pediatric Inflammatory Bowel Disease
7. The Natural History of Crohn Disease in Children
8. Natural History of Ulcerative Colitis in Children
9. Natural History of Pediatric Indeterminate Colitis
10. Extraintestinal Manifestations of Pediatric Inflammatory Bowel Disease
11. Liver Disease in Pediatric Inflammatory Bowel Disease
12. Growth Impairment in Pediatric Inflammatory Bowel Disease
13. Inflammatory Bowel Diseases and Skeletal Health
14. Puberty and Pediatric-Onset Inflammatory Bowel Disease
15. Classification of Inflammatory Bowel Disease in Children
3. Diagnosis
16. The History and Physical Exam
17. Differential Diagnosis of Inflammatory Bowel Disease
18. Laboratory Evaluation of Inflammatory Bowel Disease
19. Fecal Biomarkers in Inflammatory Bowel Disease
20. Radiologic Evaluation of Pediatric Inflammatory Bowel Disease
21. Endoscopy and Inflammatory Bowel Disease
22. The Pathology of Chronic Inflammatory Bowel Disease
23. Video Capsule Endoscopy in Inflammatory Bowel Disease
24. Bone Health in Pediatric Inflammatory Bowel Disease
4. Medical Therapy
25. 5-Aminosalicylate Therapy
26. Antibiotic Therapy
27. Nutritional Management of Inflammatory Bowel Disease
28. Probiotic Therapy
29. Corticosteroids
30. 6-Mercaptopurine Therapy
31. Methotrexate
32. Infliximab Therapy for Pediatric Crohn Disease and Ulcerative Colitis
33. Anti-TNF Biologic Therapies Other than Infliximab
34. Therapeutic Drug Monitoring in Pediatric Inflammatory Bowel Disease
35. New Non-anti-TNF-α Biological Therapies for the Treatment of Inflammatory Bowel Disease
36. Medical Treatment of Perianal Crohn’s Disease Fistulae
37. Treatment of Acute Severe Ulcerative Colitis
38. Dietary Therapies for Inflammatory Bowel Disease
39. Complementary and Alternative Therapies
5. Surgical Considerations
40. Management of Intra-abdominal Complications of Inflammatory Bowel Disease
41. Surgical Management of Crohn Disease in Children
42. Surgical Treatment of Ulcerative Colitis
43. Postoperative Surveillance and Management of Crohn’s Disease
44. Pouchitis After Ileal Pouch-Anal Anastomosis
45. Enteral Feeding Devices and Ostomies
6. Research
46. Clinical Indices for Pediatric Inflammatory Bowel Disease Research
47. Clinical Trials (Clinical Perspective)
48. Clinical Trials (Industry/Regulatory Perspective)
7. Special Considerations
49. Infectious Complications of Pediatric Inflammatory Bowel Disease
50. Psychological Aspects of Inflammatory Bowel Disease in Children and Adolescents
51. Measurement of Quality of Life in Pediatric Inflammatory Bowel Disease
52. Irritable Bowel Syndrome and Functional GI Disorders in Inflammatory Bowel Disease
53. Inflammatory Bowel Disease in Pregnancy
54. Immunizations in the Child with Inflammatory Bowel Disease
55. Malignant Tumors Arising in Inflammatory Bowel Disease
56. Quality Improvement in Inflammatory Bowel Disease
57. Fostering Self-Management and Patient Activation
58. Advocacy for Pediatric Patients with IBD
59. Legislative Advocacy
60. Transition from Pediatric to Adult Care
Backmatter
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