Introductory Bioelectronics by Pethig, Ronald R. -- Read -- Imperial Library of Trantor

Index

Cover Title Page Copyright About the Authors Foreword Preface Acknowledgements Chapter 1: Basic Chemical and Biochemical Concepts

1.1 Chapter Overview 1.2 Energy and Chemical Reactions 1.3 Water and Hydrogen Bonds 1.4 Acids, Bases and pH 1.5 Summary of Key Concepts Problems References Further Readings

Chapter 2: Cells and their Basic Building Blocks

2.1 Chapter Overview 2.2 Lipids and Biomembranes 2.3 Carbohydrates and Sugars 2.4 Amino Acids, Polypeptides and Proteins 2.5 Nucleotides, Nucleic Acids, DNA, RNA and Genes 2.6 Cells and Pathogenic Bioparticles 2.7 Summary of Key Concepts References Further Readings

Chapter 3: Basic Biophysical Concepts and Methods

3.1 Chapter Overview 3.2 Electrostatic Interactions 3.3 Hydrophobic and Hydration Forces 3.4 Osmolarity, Tonicity and Osmotic Pressure 3.5 Transport of Ions and Molecules across Cell Membranes 3.6 Electrochemical Gradients and Ion Distributions Across Membranes 3.7 Osmotic Properties of Cells 3.8 Probing the Electrical Properties of Cells 3.9 Membrane Equilibrium Potentials 3.10 Nernst Potential and Nernst Equation 3.11 The Equilibrium (Resting) Membrane Potential 3.12 Membrane Action Potential 3.13 Channel Conductance 3.14 The Voltage Clamp 3.15 Patch-Clamp Recording 3.16 Electrokinetic Effects References

Chapter 4: Spectroscopic Techniques

4.1 Chapter Overview 4.2 Introduction 4.3 Classes of Spectroscopy 4.4 The Beer-Lambert Law 4.5 Impedance Spectroscopy Problem References Further Readings

Chapter 5: Electrochemical Principles and Electrode Reactions

5.1 Chapter Overview 5.2 Introduction 5.3 Electrochemical Cells and Electrode Reactions 5.4 Electrical Control of Electron Transfer Reactions 5.5 Reference Electrodes 5.6 Electrochemical Impedance Spectroscopy (EIS) Problems References Further Readings

Chapter 6: Biosensors

6.1 Chapter Overview 6.2 Introduction 6.3 Immobilisation of the Biosensing Agent 6.4 Biosensor Parameters 6.5 Amperometric Biosensors 6.6 Potentiometric Biosensors 6.7 Conductometric and Impedimetric Biosensors 6.8 Sensors Based on Antibody–Antigen Interaction 6.9 Photometric Biosensors 6.10 Biomimetic Sensors 6.11 Glucose Sensors 6.12 Biocompatibility of Implantable Sensors References Further Readings

Chapter 7: Basic Sensor Instrumentation and Electrochemical Sensor Interfaces

7.1 Chapter Overview 7.2 Transducer Basics 7.3 Sensor Amplification 7.4 The Operational Amplifier 7.5 Limitations of Operational Amplifiers 7.6 Instrumentation for Electrochemical Sensors 7.7 Impedance Based Biosensors 7.8 FET Based Biosensors Problems References Further Readings

Chapter 8: Instrumentation for Other Sensor Technologies

8.1 Chapter Overview 8.2 Temperature Sensors and Instrumentation 8.3 Mechanical Sensor Interfaces 8.4 Optical Biosensor Technology 8.5 Transducer Technology for Neuroscience and Medicine Problems References Further Readings

Chapter 9: Microfluidics: Basic Physics and Concepts

9.1 Chapter Overview 9.2 Liquids and Gases 9.3 Fluids Treated as a Continuum 9.4 Basic Fluidics 9.5 Fluid Dynamics 9.6 Navier-Stokes Equations 9.7 Continuum versus Molecular Model 9.8 Diffusion 9.9 Surface Tension Problems References Further Readings

Chapter 10: Microfluidics: Dimensional Analysis and Scaling

10.1 Chapter Overview 10.2 Dimensional Analysis 10.3 Dimensionless Parameters 10.4 Applying Nondimensional Parameters to Practical Flow Problems 10.5 Characteristic Time Scales 10.6 Applying Micro- and Nano-Physics to the Design of Microdevices Problems References

Appendix A: SI Prefixes Appendix B: Values of Fundamental Physical Constants Appendix C: Model Answers for Self-study Problems

C.1 Chapter 1 C.2 Chapter 4 C.3 Chapter 5 C.4 Chapter 7 C.5 Chapter 8 C.6 Chapter 9 C.7 Chapter 10

Index