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Index
Studies on Epidemic Influenza COMPRISING Clinical and Laboratory Investigations
TABLE OF CONTENTS
PREFACE
HISTORY AND EPIDEMIOLOGY OF INFLUENZA
1918 Epidemic in Large Cities
The Epidemic in Universities and Colleges
1918 Epidemic at Pittsburgh
Epidemic Incidents in Institutions and Towns of Western Pennsylvania
Summary
A CLINICAL DESCRIPTION OF INFLUENZA AS IT APPEARED IN THE EPIDEMIC OF 1918–1919
Prodromal Stage and Communicability
Duration of the Disease
Forms and Varieties of Influenza
Influenza Without Lung Involvement
The Temperature
The Pulse and Respirations
Cyanosis
Leucopenia
Asthenia
Influenza with Lung Involvement
Diagnosis of Influenzal Pneumonia
Complications
Pregnancy
Sequelæ
Prognosis and Mortality of Influenza
THE URINE AND BLOOD IN EPIDEMIC INFLUENZA
Hematology
Conclusions
THE TREATMENT OF INFLUENZA
Acute Influenza
Pneumonia
Complications
THE PREVENTION OF EPIDEMIC INFLUENZA WITH SPECIAL REFERENCE TO VACCINE PROPHYLAXIS
INTRODUCTION
History of Prophylactic Vaccination in General
Prophylactic Vaccination Against Influenza
The Attempt to Develop a Specific Prophylactic Vaccine by the Use of Pure Pfeiffer Strains
Author’s Vaccine
Method of Standardization
Conclusion
The Attempt to Protect Against Epidemic Influenza by the Use of Mixed Vaccines
Data on the Prophylactic Value of Mixed Vaccines
Series I. Those Instances in Which Vaccination Was Completed Before the Epidemic Appeared
Series II. Those Instances in Which It Is Possible to Compare the Relative Occurrence in Both Vaccinated and Unvaccinated Groups After Vaccination Was Completed
Series III. Those Instances in Which Vaccination Was Begun After the Epidemic Appeared, and in Which Comparisons of Total Figures Only Are Available
The Attempt to Prevent Pneumonia as a Complication of Influenza Through the Use of Lipovaccine
Summary
Conclusions
Part II. General Prophylactic Measures
Methods Proposed for Breaking the Channels of Communication
Partial Isolation by Means of the Cubicle System
The Use of the Face Mask
General Closing Orders
The Closing of Schools
The Closing of Public Dance Halls
Regulation of Public Eating and Drinking Places
Regulation of Traffic
Enforcement of Anti-Spitting Ordinances
Increasing Natural Resistance by Augmented Healthfulness
General Measures
Public Health Administration
Desirable Laws
Education of the Public
Summary
BIBLIOGRAPHY
PHYSIOLOGICAL AND PHYSIOLOGICAL CHEMICAL OBSERVATIONS IN EPIDEMIC INFLUENZA
Results
Circulation
Respiration
Blood
Comment
THE BACTERIOLOGY OF EPIDEMIC INFLUENZA WITH A DISCUSSION OF B. INFLUENZÆ AS THE CAUSE OF THIS AND OTHER INFECTIVE PROCESSES
Introduction
General Methods of Investigation
Material Studied
Technique
Results of the Author
Direct Smears from Nasopharyngeal Swabs
The Hemophilic Bacteria
Media in Growth of B. Influenzæ
B. Influenzæ as a Pathogenic Bacterium
Infections of the Respiratory Tract
Results of Others During the Recent Pandemic
Chronic Infections
Infections of the Pleura
Sinuses of the Head
Eye and Ear
Meninges
Invasion of the Blood Stream
Endocarditis
Immunity—Phagocytosis
Agglutination
Binding of Complement
Anaphylaxis
Experiments on the Human
Conclusions
BIBLIOGRAPHY
THE PATHOLOGY OF EPIDEMIC INFLUENZA
Materials
General External Features
Muscle
Upper Respiratory Tract
Bronchi
Lung—Early Stage
Lung—Secondary Stage
Lung—Stage of Resolution
Pleura
Heart
Arteries
Lymphatics of Lung and Mediastinum
Abdominal Viscera
OBSERVATIONS UPON THE PATHOLOGY OF EIGHTEEN CASES OF INFLUENZA
Summary
BIBLIOGRAPHY
EXPLANATION OF PLATES
TRANSCRIBER’S NOTES
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