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Index
Cover
Companion website: Textbook of Obesity
Title page
Copyright page
Contributors
Editors
Foreword
Acknowledgments
Glossary
Introduction
The excitement of discovery
Part I: Understanding the Scope
Introduction
1 Epidemiology, etiology, and consequences of obesity
Introduction
Definitions and assessment
Surveying obesity prevalence
Consequences of obesity and overweight
The etiology of obesity
Conclusion
2 Cultural attitudes and biases toward obese persons
Introduction
Sources and settings of obesity stigmatization
Consequences of weight bias
Coping with weight stigma
Causes of weight bias
Changing weight bias
Conclusions and future research directions
3 The application of public health lessons to stemming the obesity epidemic
Introduction
Public health lessons learned
The search for success
Fomenting health-related social change
Applying the Framework Convention on Tobacco Control to obesity
An organizing framework for public health interventions
The need for research and evaluation
Concluding principles and issues
4 Psychodynamic approaches to the treatment of obesity
Introduction
Sex differences and obesity
Psychological understanding of obesity
Theoretical and treatment approaches
Conclusion
Part II: Etiology
Introduction
5 Genetic contributions to the development of obesity
An introduction to the genetics of obesity
Basic genetic terms
How do we study the genetics of obesity?
Designs of human studies
Findings for the genetic component of obesity
Contributions from the environment
Specific genes
The “new” genetics
Novel approaches to genomic studies
Conclusions
Acknowledgements
6 Hidden persuaders: environmental contributors to obesity
The missing environment
Why do environmental cues make us overeat?
Are we aware of the consumption norms that have led us to overeat?
How the food environment encourages mindless eating
How the eating environment stimulates consumption
Conclusions
7 White adipose tissue as a dynamic organ
Introduction
The anatomy of adipose tissue
The physiology of adipose tissue
The pathophysiology of adipose tissue
Summary
8 Appetite and body weight regulation
Basic concepts
A simplified regulatory model
Long-term weight regulatory signals
Higher-order CNS systems involved in energy homeostasis
Short-term feeding control signals
Brain nutrient sensing
Adipose tissue influences
Characteristics of the weight regulatory system
9 Eating behaviors in obesity: the role of appetite
Introduction
Appetitive characteristics and weight
The origins of obesogenic appetitive characteristics
Implications for clinical practice
10 The relation of pregnancy and lactation to obesity development in the mother and child
Pregnancy
Lactation
Summary
Part III: Health Consequences
Introduction
11 Effect of obesity on development and health in childhood
Introduction to childhood obesity
Measurement and definition issues unique to children
Biological outcomes
Social outcomes
Cognitive and psychological outcomes
12 Impact of obesity during adulthood on chronic disease: diabetes, hypertension, metabolic syndrome, cardiovascular disease, and cancer
Diabetes mellitus
Hypertension
Risk factor clustering
Conclusion
Part IV: Assessment
Introduction
13 Measurement of human body composition to assess obesity
Introduction to body composition assessment
Anthropometry
Two-compartment measurement approaches
Three- and four-compartment measurement approaches
Five-level, theoretical model
Imaging techniques
Spectroscopy
Measurement methods most applicable in clinical and research settings
Conclusion
14 Assessment of obesity risk in the community
Introduction
Definition of community
The burden of obesity in communities
Methods of community assessment
Novel approaches to community assessment
Summary
Acknowledgment
Part V: Prevention and Intervention Approaches and Settings
Introduction
15 Behavioral approaches to the treatment of obesity
Introduction
The promise and challenge of behavioral treatment: short- and long-term effectiveness
Principles and structure of behavioral treatment
Components of behavioral treatment
Dietary components of behavioral treatment
Physical activity components of behavioral treatment
Improving weight loss maintenance
Conclusion
16 Non-dieting approaches to the treatment of obesity
Assumptions
Non-dieting programs: goals and methods
Empirical support
A critical view
Conclusion
Acknowledgments
17 Dietary intervention approaches to the treatment of obesity
Introduction
Energy balance basics
Diet strategies
Categorizing diets
The diets
Conclusions
18 Pharmacological approaches to the treatment of obesity
Introduction
Energy balance equation and targets of drugs
Principles for using obesity medications
Selecting patients suitable for using medications for weight management
Benefits of modest weight loss
Drugs used
Drugs approved by the FDA for long-term treatment of overweight
Drugs approved by the FDA for Short-term treatment of overweight
Drugs approved by the FDA for a use other than obesity
Drugs with phase III clinical trials, but not approved by the FDA
Conclusions
19 Surgical treatment of severe obesity: patient selection and screening, surgical options, and nutritional management
Introduction
Patient selection
Preoperative assessment
Surgical options and outcomes
Nutritional management and follow-up
Conclusion
20 Metabolic consequences of weight reduction
Evidence that body weight is regulated
Energy homeostasis following weight reduction
Energy intake
Implications for the management of weight reduction
Summary
21 The role of physical activity in weight loss and weight loss maintenance
Introduction
Relationship between physical activity and weight change
Difference between activity and exercise
Effect of physical activity on weight
Measurement of physical activity
Methods and theories to initiate and maintain physical activity among overweight and obese
Diversity issues in physical activity and weight loss: underserved populations
Summary, recommendations, and conclusion
22 The challenge of weight loss maintenance: successful losers
Defining weight loss maintenance
Prevalence of weight loss maintenance
Maintenance of weight loss after behavioral programs
Health impact of modest weight loss
Why is maintenance so difficult?
Research on successful weight loss maintainers—The National Weight Control Registry
Research testing strategies for weight loss maintenance
Summary and conclusions
Acknowledgment
23 Treatment of obesity in the primary care setting
Introduction: Why primary caregivers rarely treat obesity
Assessment
Evaluation
Management
Conclusion
24 Worksite health promotion for obesity prevention
Introduction and background
Worksite interventions: evidence of the need for health promotion
Health promotion opportunity for worksites: guidelines for development and implementation of worksite wellness programs
Summary and conclusions
25 Treatment of overweight and obesity in children
Intervention: Selecting weight management approaches
Evidence for specific approaches to modify behavior
The practice of specific approaches to modify behaviors
Useful approaches for health providers, families, and children
Special approaches for overweight and obese children and adolescents
Conclusion—putting weight management into perspective
26 School-based interventions for overweight and obesity prevention
Introduction
Overview of school-based obesity prevention programs
An innovative approach based on inquiry-based science education—choice, control and change
Conclusion
27 Preventing childhood obesity: It Takes a Nation
Introduction
The case for prevention as a national priority
The complexity of prevention
Settings for prevention: It Takes a Nation
Obesity prevention in rural areas
Gaps in the data and research needs
Summary and conclusion
Index
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