Handbook of Cannabis Therapeutics by Grotenhermen, Franjo -- Read -- Imperial Library of Trantor

Index

Cover Half Title Title Page Copyright Page Table of Contents About the Editors Contributors Foreword Introduction Part I: Historical Notes

Introduction Materials and Methods Results Conclusion Update

Introduction Absence of Mention The Emergence of Cannabis Appendix I: Passages Discussing Wild Cannabis Possibly Misunderstood As Discussing Domesticated Cannabis Appendix II: Cannabis in Veterinary Medicine Update

Chapter 5. A Homelie Herbe: Medicinal Cannabis in Early England

Introduction Cannabis History in England The Modern Era Update

Chapter 6. Future of Cannabis and Cannabinoids in Therapeutics

Introduction New Indications for Cannabinoid Pharmaceuticals Cannabinoids and Neuroprotection Spasmodic Disorders Forbidden Territories Update

Part II: Pharmacology and Pharmacokinetics

Chapter 7. Clinical Pharmacokinetics of Cannabinoids

Introduction Pharmacokinetics of Δ9-THC Absorption Distribution Metabolism Course of Plasma Concentration of THC and Metabolites Elimination Time Effect Relationship Pharmacokinetics of Other Cannabinoids Metabolic Interactions Conclusion

Chapter 8. Clinical Pharmacodynamics of Cannabinoids

Introduction Mechanism of Action Cannabinoid Receptors Endocannabinoids Pharmacological Effects of THC Toxicity Psyche, Cognition and Behavior Central Nervous System and Neurochemistry Circulatory System Some Other Organ Systems and Effects Pharmacological Activity of THC Metabolites Pharmacological Effects of Other Cannabinoids Tolerance and Dependency Therapeutic Uses Hierarchy of Therapeutic Effects Basic Research Stage Drug Interactions Conclusions Update

Chapter 9. Cannabis and Cannabis Extracts: Greater Than the Sum of Their Parts?

Introduction Materials and Methods Results and Discussion Cannabinoids Terpenoids Flavonoids Conclusions Update

Part III: Endocannabinoids and Cannabinoid Receptors

The Endocannabinoid System Endocannabinoid Pharmacology: More Than Meets the Eye Levels of Endocannabinoids in Tissues: Physiology and Pathology New Drugs From the Endocannabinoid System: Curative or Palliative? Update

Interactions of the Endocannabinoid System with Hormones Regulating Food Intake Endocannabinoids in Food Substances Developmental Aspects of the Endocannabinoid-CB1 Receptor System Blockade of CB1 Receptors in Newborn Mice Mechanisms of the CB1 Receptor Blockade-Induced Growth-Stunting Effects Conclusions Update

Part IV: Medicinal Uses

Chapter 12. Marijuana (Cannabis) As Medicine

Introduction Indications with Evidence for Medical Efficacy Indications with Sparse Evidence of Efficacy Discussion Conclusion Update

Tennessee Michigan Georgia New Mexico (1983) New Mexico (1984) California New York Discussion Update

Chapter 14. Hyperemesis Gravidarum and Clinical Cannabis: To Eat or Not to Eat?

HG, Its Medicalization, and the Survivors Cannabis, Pregnancy, and HG Two Women’s Stories of Using Folk, Alternative Medicine Conclusion Update

AIDS in the United States Cannabinoids as Antiemetic and Appetite Stimulant in AIDS Wasting Syndrome Case Reports (The Patients’ Perspective) Recent Clinical Research on Cannabinoids, Immunity, and Weight Gain Cannabis and Harm Reduction Strategies for Persons with AIDS Conclusion Update

Chapter 16. Cannabis Treatments in Obstetrics and Gynecology: A Historical Review

Introduction The Ancient World and Medieval Middle and Far East European and Western Medicine Modern Ethnobotany of Cannabis in Obstetrics and Gynecology Recent Theory and Clinical Data Discussion and Conclusions Update

Chapter 17. Crack Heads and Roots Daughters: The Therapeutic Use of Cannabis in Jamaica

Ganja Cocaine Women and Crack Conclusions Implications Update

Chapter 18. Cannabis in Multiple Sclerosis: Women’s Health Concerns

Introduction Treatment Options: Acute Episodes, Disease Modification and Symptom Management Cannabis in Acute Treatment and Disease Modification Cannabis in Symptom Management Impaired Mobility: Spasticity Tremor Nystagmus Postural Regulation Fatigue Pain Bladder Dysfunction Sexual Dysfunction Discussion Conclusions Update

Part V: Side Effects

Chapter 19. Cannabis and Harm Reduction: A Nursing Perspective

Introduction Cannabis Was a Medicine in the United States Cannabis As a Harm Reduction Medicine Cannabis As a Social/Recreational Drug Cannabis Prohibition Causes More Harm Than the Drug Conclusions

Introduction Previous Chronic Cannabis Use Studies A Brief History of the Compassionate IND Methods Results And Discussion Conclusions and Recommendations Update

Afterword Index