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Index
Cover
Title Page
Copyright
List of Contributors
Foreword
Preface
Chapter 1: The Unique Nature of Glass
1.1 What Is Glass?
1.2 Making Glass
1.3 Homogeneity and Phase Separation
1.4 Forming
1.5 Glasses That Are Not “Melted”
1.6 Exotic Glass
1.7 Summary
Further Reading
Chapter 2: Melt-Derived Bioactive Glass
2.1 Bioglass
2.2 Network Connectivity and Bioactivity
2.3 Alternative Bioactive Glass Compositions
2.4 In Vitro Studies
2.5 In Vivo Studies and Commercial Products
References
Chapter 3: Sol-Gel Derived Glasses for Medicine
3.1 Introduction
3.2 Why Use the Sol-Gel Process?
3.3 Sol-Gel Process Principles
3.4 Steps in a Typical Sol-Gel Process
3.5 Evolution of Nanoporosity
3.6 Making Sol-Gel Monoliths
3.7 Making Particles
3.8 Sol-Gel Derived Bioactive Glasses
3.9 Summary
References
Chapter 4: Phosphate Glasses
4.1 Introduction
4.2 Making Phosphate Glasses
4.3 Phosphate Glass Structure
4.4 Temperature Behaviour and Crystallisation
4.5 Phosphate Glass Dissolution
4.6 Cell Compatibility of Glasses
4.7 Phosphate Glass Fibres and Composites
4.8 Applications
4.9 Summary
References
Chapter 5: The Structure of Bioactive Glasses and Their Surfaces
5.1 Structure of Glasses
5.2 Structure of Bioactive Glasses
5.3 Computer Modeling (Theoretical Simulation) of Bioactive Glasses
5.4 Glass Surfaces
5.5 Summary
References
Chapter 6: Bioactive Borate Glasses
6.1 Introduction
6.2 What Differentiates a Bioactive Borate Glass from Other Bioactive Glasses?
6.3 Evaluating Reactive Materials (In Vitro Versus In Vivo Testing)
6.4 Multifunctional Bioactive Borate Glasses
6.5 Applications of Bioactive Borate Glasses in Orthopedics and Dental Regeneration
6.6 Soft Tissue Wound Healing
6.7 Tissue/Vessel Guidance
6.8 Drug Delivery
6.9 Commercial Product Design
6.10 Summary
References
Chapter 7: Glass-Ceramics
7.1 Glass-Ceramics and Their Uses
7.2 Methods Used for the Controlled Crystallization of Glasses
7.3 A Glass-Ceramic That Hardly Expands When Heated
7.4 High-Strength, Moldable Glass-Ceramics for Dental Restoration
7.5 Glass-Ceramics That Are Moldable and Machinable
7.6 Outlook
References
Chapter 8: Bioactive Glass and Glass-Ceramic Coatings
8.1 Introduction
8.2 Enameling
8.3 Glazing
8.4 Plasma Spraying
8.5 Radiofrequency Magnetron Sputtering Deposition
8.6 Pulsed Laser Deposition
8.7 Summary
References
Chapter 9: Composites Containing Bioactive Glass
9.1 Introduction
9.2 Biodegradable Polymers
9.3 Composite Scaffolds Containing Bioactive Glass
9.4 Processing Technologies for Porous Bioactive Composites
9.5 Case Study: the PDLLA-Bioglass Composite Scaffold System
9.6 Final Remarks
References
Chapter 10: Inorganic-Organic Sol-Gel Hybrids
10.1 Introduction
10.2 Hybrids in Medicine and Why They Should Be Silica-Based
10.3 Self-Assembled Hybrid Films and Layers of Grafted Silanes
10.4 Sol-Gel Hybrids
10.5 Ormosils
10.6 Polymer Choice and Property Control in Hybrids
10.7 Maintaining Bioactivity in Sol-Gel Hybrids
10.8 Summary and Outlook
Further Reading
Chapter 11: Dental Applications of Glasses
11.1 Introduction
11.2 Structure of the Human Tooth
11.3 Glass Bioactivity and Teeth
11.4 Bioactive Glass in Dental Bone Regeneration
11.5 Treatment of Hypersensitive Teeth
11.6 Bioactive Glass Coating on Metal Implants
11.7 Antimicrobial Properties of Bioactive Glasses
11.8 Bioactive Glasses in Polymer Composites
11.9 Bioactive Glasses in Glass Ionomer Cements
11.10 Summary
References
Chapter 12: Bioactive Glass as Synthetic Bone Grafts and Scaffolds for Tissue Engineering
12.1 Introduction
12.2 Synthetic Bone Grafts and Regenerative Medicine
12.3 Design Criteria for an Ideal Synthetic Bone Graft
12.4 Bioglass and the Complication of Crystallisation During Sintering
12.5 Making Porous Glasses
12.6 The Future: Porous Hybrids
12.7 Bioactive Glasses and Tissue Engineering
12.8 Regulatory Issues
12.9 Summary
Further Reading
Chapter 13: Glasses for Radiotherapy
13.1 Introduction
13.2 Glass Design and Synthesis
13.3 Non-Degradable or Bio-inert Glasses: Rare Earth Aluminosilicate Glasses
13.4 Biodegradable Glasses: Rare Earth Borate/Borosilicate Glasses
13.5 Design of Radioactive Glass Microspheres for In Vivo Applications
13.6 Treatment of Liver Cancer: Hepatocellular Carcinoma
13.7 Treatment of Kidney Cancer: Renal Cell Carcinoma
13.8 Treatment of Rheumatoid Arthritis: Radiation Synovectomy
13.9 Summary
References
Supplemental Images
Index
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