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Index
Title page
Table of Contents
Copyright
Preface
Acknowledgements
International Advisers
Contributors
Index of Patient Symptoms
Part 1: Basic Pathology
Chapter 1: What is pathology?
History of pathology
Scope of pathology
Techniques of pathology
Learning pathology
Making diagnoses
Pathology and populations
Chapter 2: What is disease?
What is disease?
Characteristics of disease
Nomenclature of disease
Principles of disease classification
Epidemiology
Chapter 3: What causes disease?
Causes of disease
Genetic abnormalities in disease
Environmental factors
Infective agents
Part 2: Disease Mechanisms
Chapter 4: Disorders of growth, differentiation and morphogenesis
Definitions
Normal growth, differentiation and morphogenesis
Abnormalities of growth, differentiation and morphogenesis
Chapter 5: Responses to cellular injury
Cellular injury
Repair and regeneration
Injury due to ionising radiation
Chapter 6: Disorders of metabolism and homeostasis
Inborn errors of metabolism
Acquired metabolic disorders
Metabolic consequences of malnutrition
Obesity
Trace elements and disease
Tissue depositions
Chapter 7: Ischaemia, infarction and shock
Non-thromboembolic vascular insufficiency
Thromboembolic vascular occlusion
Infarction
Shock
Chapter 8: Immunology and immunopathology
Defence against infection
Key molecules
Structural organisation of the immune system
Functional organisation of the immune response
Non-specific effector mechanisms
Outcomes of immune responses
Immunodeficiency
Hypersensitivity reactions
Autoimmunity and autoimmune disease
Principles of organ transplantation
Chapter 9: Inflammation
Acute inflammation
Chronic inflammation
Chapter 10: Carcinogenesis and neoplasia
General characteristics of neoplasms (tumours)
Classification of tumours
Nomenclature of tumours
Biology of tumour cells
Carcinogenesis
Cellular and molecular events in carcinogenesis
Behaviour of tumours
Early detection of cancer by screening
Hallmarks
Chapter 11: Ageing and death
Theories of ageing
Death
Chapter 12: How do pathologists help patient care?
Types of laboratory tests
Specialised tests
Autopsies
Part 3: Systematic Pathology
Chapter 13: Cardiovascular system
Diseases of the arteries and other vessels
Cardiac disease
Chapter 14: Respiratory tract
Diseases of infancy and childhood
Nasal passages, middle ear and sinuses
Larynx
The lungs
Chapter 15: Alimentary system
Mouth, teeth, pharynx and salivary glands
Oesophagus
Stomach
Intestine
Appendix
Anus and anal canal
Chapter 16: Liver, biliary system and pancreas
Common clinical problems from liver and biliary system disease
Liver
Biliary system
Paediatric liver disease
Exocrine pancreas
Chapter 17: Endocrine system
Pituitary
Pineal gland
Adrenals
Thyroid
Parathyroids
Endocrine pancreas
Chapter 18: Breast
Common clinical problems from breast disease
Normal structure and function
Clinical features of breast lesions
Diagnostic methods
Inflammatory conditions
Proliferative conditions of the breast
Benign tumours
Breast carcinoma
Other tumours
Chapter 19: Female genital tract
Common clinical problems from female genital tract disease
Normal development
Vulva
Non-neoplastic epithelial disorders
Neoplastic epithelial disorders
Vagina and cervix
Cervical squamous neoplasia
Glandular neoplasia of the cervix
Other malignant tumours
Uterine corpus
Congenital abnormalities
The normal endometrium and menstrual cycle
Abnormalities of the endometrium
Abnormalities of the myometrium
Ovary
Ovarian cysts
Ovarian stromal hyperplasia and stromal luteinisation
Endometriosis
Ovarian neoplasms
Fallopian tubes
Pathology of pregnancy
Hydatidiform mole
Pathology of the full-term placenta
Pathology of the umbilical cord and membranes
Pathology of the placental bed
Ectopic pregnancy
Maternal death
Chapter 20: Urinary and male genital tracts
Urinary calculi
Renal tumours
Ureters
Bladder
Tumours of the bladder
Prostate gland
Penis and scrotum
Urethra
Testis
Epididymis and cord
Chapter 21: Kidney diseases
Common clinical problems from kidney disease
Introduction
Functions of the kidney
Glomerular diseases
Tubular disorders
Vascular diseases
Urinary tract obstruction and infections
Cystic renal diseases
Congenital anomalies
Renal transplantation
Chapter 22: Lymph nodes and extranodal lymphoid tissue, spleen and thymus
Lymph nodes
Spleen
Thymus
Chapter 23: Blood and bone marrow
Composition, production and functions of blood
Neoplastic disorders of the bone marrow
Disorders of blood coagulation and haemostasis
Chapter 24: Skin
Common clinical problems from skin disease
Normal structure and function
Clinical aspects of skin diseases
Disorders involving inflammatory and haemopoietic cells
Infections
Non-infectious inflammatory diseases
Epidermal cells
Melanocytes
Dermal vessels
Adnexa
Dermal connective tissues
Deposits
Cutaneous nerves
Behaviour and the skin
Toxins and the skin
Skin manifestations of internal and systemic disease
Chapter 25: Osteoarticular and connective tissues
Bone
Joints
Connective tissues
Chapter 26: Central and peripheral nervous systems
Central nervous system
Peripheral nervous system
Skeletal muscle
The eye
The ear
Glossary
Index
Instructions for online access
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